Flumelone
Rx100 mg • Eye Drops
More from Flumelone
Other strengths and forms by Reman Drug Laboratories Ltd.
Indications & Uses
Flumelone is indicated for:
Pharmacology
The exact mechanism by which ocular corticosteroids work is not fully agreed upon. However, they are thought to act by inducing phospholipase A2-inhibitory proteins known collectively as lipocortins. These proteins are believed to regulate the production of potent inflammatory mediators such as prostaglandins and leukotrienes, by blocking the release of their shared precursor, arachidonic acid, which is otherwise released from membrane phospholipids by phospholipase A2. Corticosteroids act mainly on the cytosolic glucocorticoid receptor; once bound, the resulting receptor-ligand complex moves into the cell nucleus, where it attaches to glucocorticoid response elements (GRE) in the promoter region of target genes. The DNA-bound receptor then interacts with basic transcription factors, increasing the expression of specific target genes.
Neomycin, like other aminoglycoside antibiotics, works by binding to the 30S ribosomal subunit of susceptible bacteria, disrupting the machinery responsible for bacterial protein synthesis. Normally, bacterial translation begins with mRNA binding to the 30S subunit, followed by binding of the 50S subunit for elongation.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dosage: Adults usually take one to two drops in the affected eye, two to four times daily. In the first 24 to 48 hours, this may be safely increased to one drop every hour, or as directed by the physician.
Side Effects
Increased eye pressure (glaucoma), loss of part of your usual field of vision, blurred vision, and cataracts (a clouding of the eye's lens) may occur. You may also notice eye irritation, redness, pain, or a feeling that something is in the eye, along with swelling of the eyelid or eye and itching or watering. Ulcers can develop on the eye's surface, and secondary infections from fungi or viruses may set in. Other possible effects include skin rash, allergic reactions, and a change in your sense of taste.
Cautions & Contraindications
Warnings & Precautions
If you use this ophthalmic solution over a long period, it may raise the pressure inside your eye (intraocular pressure), which can lead to glaucoma, so your eye pressure should be checked regularly. It may also cause cataracts (a clouding of the lens), blurred vision, or delayed healing of eye wounds. Damage to the front part of the eye from fungal infection may occur during or after use of this solution. It may increase the risk of corneal damage, cause thinning of the cornea, or lead to small ulcers on the eye's surface. It may also suppress the body's immune response, which can lead to secondary eye infections.
Contraindications
Do not use this ophthalmic solution if you are hypersensitive (allergic) to fluorometholone, neomycin sulfate, or any of the other ingredients in this preparation, or if you have an eye infection (with pus) caused by micro-organisms not sensitive to the antibiotic neomycin. It should also be avoided if you have an active viral or fungal infection of the eye, tuberculosis of the eye, or glaucoma, or if you are pregnant or breastfeeding.
Pregnancy & Breastfeeding
This eye solution should not be used during pregnancy or while breastfeeding. It is not known whether the active ingredients in this preparation pass into breast milk, so it is not recommended for mothers who are breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
The safety and efficacy of Fluormetholone + Neomycin Sulphate in children aged 2 years or younger have not been established.
Storage
Keep Fluormetholone + Neomycin Sulphate at or below 25°C, and don't let it freeze. Once you've opened the bottle, stop using it after 30 days, even if some liquid is still left inside.
Common questions about Flumelone 100 mg
What is Flumelone 100 mg Eye Drops?
Flumelone 100 mg Eye Drops is a medicine that contains Fluormetholone + Neomycin Sulphate. It is made by Reman Drug Laboratories Ltd. It belongs to the Ophthalmic steroid - antibiotic combined preparations group of medicines.
What is Flumelone used for?
Flumelone is used for: Bacterial Infection, Conjunctivitis.
What are the side effects of Flumelone?
Increased eye pressure (glaucoma), loss of part of your usual field of vision, blurred vision, and cataracts (a clouding of the eye's lens) may occur. You may also notice eye irritation, redness, pain, or a feeling that something is in the eye, along with swelling of the eyelid or eye and itching or watering.
Can I take Flumelone during pregnancy or while breastfeeding?
This eye solution should not be used during pregnancy or while breastfeeding. It is not known whether the active ingredients in this preparation pass into breast milk, so it is not recommended for mothers who are breastfeeding. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Flumelone?
Keep Fluormetholone + Neomycin Sulphate at or below 25°C, and don't let it freeze. Once you've opened the bottle, stop using it after 30 days, even if some liquid is still left inside.
Do I need a prescription for Flumelone?
Flumelone is a prescription (Rx) medicine. Take it as your doctor advises.