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Pharmacology
Amoxicillin is a broad-spectrum penicillin active against a wide range of Gram-positive and Gram-negative bacteria. It works by blocking the bacteria's cell wall formation. Stable in stomach acid, it is absorbed quickly when taken by mouth, with peak blood levels reached within 1 to 2 hours of a dose. From there, it spreads widely through body tissues and fluids, though concentrations vary from one site to another.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dosage Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections. Children (up to 10 years of age): 125 mg three times daily, increasing up to 250 mg three times daily for severe infections. Severe or recurrent purulent respiratory infection: 3 gm every 12 hours. Otitis media: the recommended dose is 1 g three times daily for adults and 40 mg/kg body weight daily in 3 divided doses for children (max 3 g daily). Pneumonia: the recommended dose is 500 to 1000 mg three times daily. Dental abscess: the recommended dose is 3 gm, repeated after 10 to 12 hours. Urinary tract infections: the recommended dose is 3 gm, repeated after 10 to 12 hours. Gonorrhoea: a single dose of 2 to 3 gm with Probenecid 1 gm is recommended (Probenecid is contraindicated in children under 2 years). In renal impairment, it may be necessary to reduce the total daily dosage.
Side Effects
Side effects are usually mild and go away on their own. Some people may notice diarrhoea, an upset stomach, or occasionally a skin rash. Rarely, a more serious bowel inflammation called pseudo-membranous colitis has been reported.
Cautions & Contraindications
Warnings & Precautions
The possibility of superinfection with fungal or bacterial pathogens should be kept in mind during treatment. If a superinfection occurs, Simox DS should be stopped and suitable alternative therapy started.
Contraindications
Amoxicillin should not be used by patients who are hypersensitive to penicillin.
Pregnancy & Breastfeeding
Amoxicillin falls under FDA pregnancy category B. That said, well-controlled studies in pregnant women are lacking, and since animal studies don't always predict how humans will respond, it's best used in pregnancy only when clearly needed. Amoxicillin does pass into breast milk, so it should be given to breastfeeding mothers with caution.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Amoxicillin Trihydrate in a dry place, away from light and heat. Keep it out of the reach of children.
Drug Interactions
Common questions about Fimoxyl DS 250 mg/5 ml
What is Fimoxyl DS 250 mg/5 ml Powder For Suspension?
Fimoxyl DS 250 mg/5 ml Powder For Suspension is a medicine that contains Amoxicillin Trihydrate. It is made by Synovia Pharma PLC. It belongs to the Broad spectrum penicillins group of medicines.
What is Fimoxyl DS used for?
Fimoxyl DS is used for: Chronic Obstructive Pulmonary Disease, Pneumonia, Bronchitis, Sinusitis, Pharyngitis, Tonsillitis, Peptic Ulcer, Helicobacter Pylori Infection, Urinary Tract Infection, Respiratory Tract Infection.
What are the side effects of Fimoxyl DS?
Side effects are usually mild and go away on their own. Some people may notice diarrhoea, an upset stomach, or occasionally a skin rash.
Can I take Fimoxyl DS during pregnancy or while breastfeeding?
Amoxicillin falls under FDA pregnancy category B. That said, well-controlled studies in pregnant women are lacking, and since animal studies don't always predict how humans will respond, it's best used in pregnancy only when clearly needed. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Fimoxyl DS?
Store Amoxicillin Trihydrate in a dry place, away from light and heat. Keep it out of the reach of children.
Can I take other medicines with Fimoxyl DS?
Some medicines can interact with Amoxicillin Trihydrate, for example: Progesterone. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Fimoxyl DS?
Fimoxyl DS is a prescription (Rx) medicine. Take it as your doctor advises.