Save on this medicine
Other brands with the same active ingredient
These brands contain the same active ingredient (Gemfibrozil). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Gelicon is a hypolipidemic medicine used alongside diet control. It is prescribed for type IIa, type IIb, type III, type IV and type V hyperlipoproteinemia.
Pharmacology
Gemfibrozil is an anti-lipemic agent that lowers serum triglycerides in both healthy individuals and patients with hyper-triglyceridemia. It reduces very low-density lipoprotein (VLDL) triglyceride concentration and, to a lesser extent, LDL triglyceride concentration, while HDL-triglyceride is usually lowered slightly. It typically raises the HDL-cholesterol fraction in healthy individuals and patients with hyperlipoproteinemia, an effect that may help slow the progression of atherosclerosis and reduce the risk of coronary heart disease.
Gemfibrozil also inhibits synthesis of the VLDL carrier apolipoprotein B, which leads to decreased VLDL production. The mechanism by which it raises HDL concentration is not known. It inhibits lipolysis of fat in adipose tissue and reduces hepatic uptake of plasma free fatty acids, thereby lowering hepatic triglyceride production.
Gemfibrozil is rapidly and completely absorbed from the gastrointestinal tract, reaching peak plasma concentration within 1 to 2 hours and having a half-life of about 1.5 hours. About 70% of a dose is excreted in the urine, with only a small amount excreted in the faeces.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The usual dose taken by mouth is 1.2 gm daily, split into 2 doses, taken 30 minutes before the morning and evening meals. Depending on response, the physician may adjust the dose anywhere between 0.9 and 1.5 gm daily.
Side Effects
Gemfibrozil most often affects the digestive system, causing abdominal discomfort or an upset stomach, often felt as pain in the upper abdomen. Less commonly, it may cause itching, skin rash, headache, dizziness, blurred vision, and pain in the arms or legs; muscle aches occur rarely.
Cautions & Contraindications
Warnings & Precautions
Risk versus benefit should be weighed for breastfeeding mothers before this medicine is used. Before starting long-term treatment, it is advisable to check lipid profile, blood counts, kidney function, and liver function tests, along with an annual eye examination.
Contraindications
Gemfibrozil should not be used by people with a history of alcoholism, liver problems, gallstones, or known hypersensitivity to the drug. It is also contraindicated during pregnancy.
Pregnancy & Breastfeeding
Safety in human pregnancy has not been firmly established, and it isn't known whether gemfibrozil passes into breast milk. As with most medicines, it's generally best to avoid gemfibrozil during pregnancy and while breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Gemfibrozil below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Fibril 300 mg
What is Fibril 300 mg Capsule?
Fibril 300 mg Capsule is a medicine that contains Gemfibrozil. It is made by Beximco Pharmaceuticals Ltd. It belongs to the Dyslipidaemic Agents group of medicines.
What is Fibril used for?
Gelicon is a hypolipidemic medicine used alongside diet control. It is prescribed for type IIa, type IIb, type III, type IV and type V hyperlipoproteinemia.
What are the side effects of Fibril?
Gemfibrozil most often affects the digestive system, causing abdominal discomfort or an upset stomach, often felt as pain in the upper abdomen. Less commonly, it may cause itching, skin rash, headache, dizziness, blurred vision, and pain in the arms or legs; muscle aches occur rarely.
Can I take Fibril during pregnancy or while breastfeeding?
Safety in human pregnancy has not been firmly established, and it isn't known whether gemfibrozil passes into breast milk. As with most medicines, it's generally best to avoid gemfibrozil during pregnancy and while breastfeeding. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Fibril?
Store Gemfibrozil below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Fibril?
Some medicines can interact with Gemfibrozil, for example: Atorvastatin + Ezetimibe, Daprodustat, Resmetirom, Paclitaxel, Apalutamide, Nab-Paclitaxel [Nanoparticle Albumin-Bound Paclitaxel]. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Fibril?
Fibril is a prescription (Rx) medicine. Take it as your doctor advises.