Pricing
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All price changes →Indications & Uses
Eradra is indicated for:
Pharmacology
Lifitegrast binds to LFA-1, an integrin, which is a cell surface protein found on leukocytes. By binding there, it blocks LFA-1 from interacting with its cognate ligand, intercellular adhesion molecule-1 (ICAM-1). In DED, ICAM-1 may be overexpressed in corneal and conjunctival tissues. The LFA-1/ICAM-1 interaction can contribute to the formation of an immunological synapse, and this results in T-cell activation and migration to target tissues.
In vitro studies showed that lifitegrast may inhibit Tcell adhesion to ICAM-1 in a human T-cell line. It may also inhibit secretion of inflammatory cytokines in human peripheral blood mononuclear cells. The exact mechanism of action of lifitegrast in DED is not known.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Put one drop of Lifitegrast into each eye twice a day, about 12 hours apart. Take out your contact lenses before using Lifitegrast. You can put them back in 15 minutes after the drop.
Side Effects
The most common side effects of Lifitegrast are irritation where the drops go into the eye, an altered or unpleasant taste (dysgeusia), and reduced visual acuity. Less often, people report blurred vision, redness of the eye (conjunctival hyperemia), headache, increased tear production, eye discharge, eye discomfort, itching of the eye and sinusitis.
Cautions & Contraindications
Warnings & Precautions
Don't let the dropper tip touch any surface, because this can contaminate the Lifitegrast solution. Once a dropper has been open for one month, stop using the medicine from it.
Contraindications
Don't use Lifitegrast if you are hypersensitive to it, to any other ingredient in the formulation, or to any component of the container.
Pregnancy & Breastfeeding
We don't have any data on the use of Lifitegrast in pregnant women, so it isn't known whether the medicine carries any risk in pregnancy. Nothing is known either about whether Lifitegrast passes into human milk, what effect it might have on a breastfed infant, or whether it changes milk production.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Pediatric use: Lifitegrast has not been shown to be safe or effective in patients below 17 years of age.
Geriatric use: Doctors have seen no overall difference in safety or effectiveness between elderly patients and younger adults.
Overdose
We don't have any information on what happens if someone takes too much Lifitegrast. If you think an overdose may have happened, contact your ophthalmologist for advice on what to do.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Lifitegrast in a cool, dry place where the temperature stays below 30°C, and away from light. Keep it out of the reach of children.
Common questions about Eradra 5%
What is Eradra 5% Ophthalmic Solution?
Eradra 5% Ophthalmic Solution is a medicine that contains Lifitegrast. It is made by General Pharmaceuticals Ltd. It belongs to the Other ophthalmic preparations group of medicines.
What is Eradra used for?
Eradra is used for: Dry Eye.
What are the side effects of Eradra?
The most common side effects of Lifitegrast are irritation where the drops go into the eye, an altered or unpleasant taste (dysgeusia), and reduced visual acuity. Less often, people report blurred vision, redness of the eye (conjunctival hyperemia), headache, increased tear production, eye discharge, eye discomfort, itching of the eye and sinusitis.
Can I take Eradra during pregnancy or while breastfeeding?
We don't have any data on the use of Lifitegrast in pregnant women, so it isn't known whether the medicine carries any risk in pregnancy. Nothing is known either about whether Lifitegrast passes into human milk, what effect it might have on a breastfed infant, or whether it changes milk production. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Eradra?
We don't have any information on what happens if someone takes too much Lifitegrast. If you think an overdose may have happened, contact your ophthalmologist for advice on what to do. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Eradra?
Keep Lifitegrast in a cool, dry place where the temperature stays below 30°C, and away from light. Keep it out of the reach of children.
Do I need a prescription for Eradra?
Eradra is a prescription (Rx) medicine. Take it as your doctor advises.