Pricing
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Emprila is indicated for:
Pharmacology
Lidocaine and prilocaine belong to the amide group of local anaesthetics. They work by stabilising nerve cell membranes and blocking the ion movements needed to start and carry nerve impulses, which is what produces the numbing effect.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults: A thick layer of Lidocaine & Prilocaine cream is applied to intact skin and covered with an occlusive dressing.
For minor dermal procedures such as intravenous cannulation and venipuncture, apply 2.5 grams of Lidocaine & Prilocaine cream over 20 to 25 cm2 of skin surface for at least 1 hour.
For major dermal procedures, that is, more painful dermatological procedures involving a larger skin area, apply 2 grams of Lidocaine & Prilocaine cream per 10 cm2 of skin and allow it to remain in contact with the skin for at least 2 hours.
For adult male genital skin, as an adjunct prior to local anesthetic infiltration, apply a thick layer of Lidocaine & Prilocaine cream to the skin surface for 15 minutes. Local anesthetic infiltration should be performed immediately after the cream is removed.
For adult female genital mucous membranes, for minor procedures on the female external genitalia, such as removal of condylomata acuminata, and also as pretreatment for anesthetic infiltration, apply a thick layer of 5 to 10 grams of Lidocaine & Prilocaine cream for 5 to 10 minutes. Occlusion is not necessary for absorption, but it may be helpful to keep the cream in place. Patients should be lying down during application, especially if no occlusion is used. The procedure or the local anesthetic infiltration should be performed immediately after the cream is removed.
Pediatric patients: the following are the maximum recommended doses, application areas and application times for Lidocaine & Prilocaine cream, based on a child's age and weight. For 0 to 3 months of age or under 5 kg, the maximum total dose is 1 gram, with a maximum application time of 1 hour. For 3 to 12 months of age and over 5 kg, the maximum total dose is 2 grams, with a maximum application time of 4 hours. For 1 to 6 years of age and over 10 kg, the maximum total dose is 10 grams, with a maximum application time of 4 hours. For 7 to 12 years of age and over 20 kg, the maximum total dose is 20 grams, with a maximum application time of 4 hours.
Side Effects
Nervousness, dizziness, blurred vision, tremors, drowsiness, convulsions, unconsciousness, respiratory arrest, low blood pressure, weakened heart muscle activity, slow heart rate, cardiac arrest, and allergic-type reactions such as skin lesions, hives, or swelling may occur.
Cautions & Contraindications
Warnings & Precautions
Absorption from wound surfaces and mucous membranes is relatively high, especially in the bronchial tree. This cream should be used with caution in patients with traumatised mucosa and/or sepsis in the region where it will be applied. If the dose or site of application is likely to result in high blood levels, the cream should be used cautiously in patients with epilepsy, impaired cardiac condition, bradycardia, impaired hepatic function, and in severe shock. The use of oropharyngeal topical anesthetic agents may interfere with swallowing and thus increase the risk of aspiration. This is particularly important in children, given how frequently they eat. Numbness of the tongue or buccal mucosa may increase the risk of biting trauma.
Contraindications
Do not use this medicine if you are allergic to lidocaine, prilocaine, or any other amide-type local anaesthetic, or to any other ingredient in the product.
Pregnancy & Breastfeeding
Lidocaine + Prilocaine cream has not been formally proven safe for use in pregnancy, but decades of widespread clinical use have not shown any obvious harm. If a medicine is genuinely needed during pregnancy and no safer option is available, this one may be used. A small amount does pass into breast milk, but the quantity is so low that it is not generally expected to affect a nursing infant at normal treatment doses.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
When lidocaine goes above 5 µg/ml and/or prilocaine goes above 6 µg/ml, the levels are toxic. At these levels, cardiac output, total peripheral resistance and mean arterial pressure may all fall. The cause is the direct depressant effect these local anaesthetic agents have on the CVS.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Lidocaine + Prilocaine in a cool, dry place and away from light.
Common questions about Emprila 2.5%+2.5%
What is Emprila 2.5%+2.5% Cream?
Emprila 2.5%+2.5% Cream is a medicine that contains Lidocaine + Prilocaine. It is made by Unimed Unihealth Pharmaceuticals Ltd. It belongs to the Local & Surface anesthesia group of medicines.
What is Emprila used for?
Emprila is used for: Pain.
What are the side effects of Emprila?
Nervousness, dizziness, blurred vision, tremors, drowsiness, convulsions, unconsciousness, respiratory arrest, low blood pressure, weakened heart muscle activity, slow heart rate, cardiac arrest, and allergic-type reactions such as skin lesions, hives, or swelling may occur.
Can I take Emprila during pregnancy or while breastfeeding?
Lidocaine + Prilocaine cream has not been formally proven safe for use in pregnancy, but decades of widespread clinical use have not shown any obvious harm. If a medicine is genuinely needed during pregnancy and no safer option is available, this one may be used. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Emprila?
When lidocaine goes above 5 µg/ml and/or prilocaine goes above 6 µg/ml, the levels are toxic. At these levels, cardiac output, total peripheral resistance and mean arterial pressure may all fall. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Emprila?
Keep Lidocaine + Prilocaine in a cool, dry place and away from light.
Do I need a prescription for Emprila?
Emprila is a prescription (Rx) medicine. Take it as your doctor advises.