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Indications & Uses
Elimate is indicated for:
Pharmacology
Permethrin cream contains permethrin, a pyrethroid compound used topically to treat infestation with Sarcoptes scabiei (scabies). It works on the nerve cell membrane of the parasite, disrupting the sodium channel current that normally regulates the membrane's polarization. This disturbance delays repolarization and leads to paralysis of the mites.
Pharmacokinetics: Topical application is the only approved route of administration, and human data on systemic exposure or kinetics after skin application remain limited. Some metabolism takes place in the skin before absorption. Less than 0.5% of the applied dose is absorbed within the first 48 hours. Once absorbed, permethrin is rapidly broken down through ester hydrolysis, most likely in the liver, and the resulting products are excreted mainly in the urine.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Recommended treatment duration by age: adults and children over 12 years should use a full tube; children aged 6 to 12 years, up to half a tube; children aged 1 to 5 years, up to one quarter of a tube; and children aged 2 months to 1 year, up to one eighth of a tube. For children less than 2 months old, the recommended dose has not been established.
Side Effects
In people being treated for scabies, a few individuals notice skin discomfort soon after the cream is applied, usually described as burning, stinging or tingling. Other temporary signs of irritation may include redness, swelling, eczema, rash and itching.
Cautions & Contraindications
Warnings & Precautions
Scabies is often accompanied by itching, swelling and redness. Treatment with Remathrin may make these symptoms worse for a short time. Keep the cream out of the eyes when you apply it. If it does get into the eyes, rinse them straight away with plenty of water.
Contraindications
Permethrin should not be used in anyone with a known hypersensitivity to pyrethroids, permethrin, or any of its other ingredients. Nursing staff who apply permethrin regularly may wear gloves to protect their hands from possible irritation.
Pregnancy & Breastfeeding
Pregnancy: No specific studies have looked at permethrin use during pregnancy, so it should only be used if a doctor advises it.
Breastfeeding: It isn't known whether permethrin passes into breast milk, so breastfeeding mothers should avoid using it.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Permethrin in a cool, dry place, away from light. Keep it out of the reach of children.
Drug Interactions
Common questions about Elimate 5%
What is Elimate 5% Cream?
Elimate 5% Cream is a medicine that contains Permethrin. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Parasiticidal preparations group of medicines.
What is Elimate used for?
Elimate is used for: Scabies.
What are the side effects of Elimate?
In people being treated for scabies, a few individuals notice skin discomfort soon after the cream is applied, usually described as burning, stinging or tingling. Other temporary signs of irritation may include redness, swelling, eczema, rash and itching.
Can I take Elimate during pregnancy or while breastfeeding?
Pregnancy: No specific studies have looked at permethrin use during pregnancy, so it should only be used if a doctor advises it. Breastfeeding: It isn't known whether permethrin passes into breast milk, so breastfeeding mothers should avoid using it. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Elimate?
Keep Permethrin in a cool, dry place, away from light. Keep it out of the reach of children.
Can I take other medicines with Elimate?
Some medicines can interact with Permethrin, for example: Permethrin + Crotamiton. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Elimate?
Elimate is a prescription (Rx) medicine. Take it as your doctor advises.