Indications & Uses
Edac is indicated for:
Pharmacology
Similar to other NSAIDs, etodolac's anti-inflammatory action comes from blocking the enzyme cyclooxygenase (COX), which reduces the production of prostaglandins in body tissues that help drive inflammation. It works by attaching to the upper part of the COX active site, blocking its substrate, arachidonic acid, from reaching that site. Etodolac was once considered a non-selective COX inhibitor, but is now recognized as being 5 to 50 times more selective for COX-2 than COX-1. Its fever-reducing effect is thought to arise from action on the hypothalamus in the brain, which widens peripheral blood vessels, boosts blood flow to the skin, and allows heat to escape the body.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and over 18 years: for the Etodolac 300 mg capsule, the usual dose is 600 mg daily, taken in 1 to 2 divided doses. For the Etodolac 600 mg ER tablet, it is taken once daily. Pediatric: safety and effectiveness in pediatric patients below the age of 18 years have not been established.
Side Effects
Panodin SR mainly affects the digestive system. It may cause stomach pain, constipation, diarrhea, indigestion, gas, heartburn, nausea, vomiting, and stomach or intestinal ulcers. Less commonly, it may lead to abnormal kidney function, anemia, dizziness, swelling (edema), raised liver enzymes, headaches, longer bleeding time, itching, skin rashes, and ringing in the ears.
Cautions & Contraindications
Warnings & Precautions
Panodin SR should be used cautiously in patients with a history of severe hepatic reactions, pre-existing asthma, fluid retention, high blood pressure, or heart failure. It should be stopped if signs and symptoms of liver disease appear, or if systemic reactions such as eosinophilia or rash develop.
Contraindications
Etodolac should not be used by anyone with a known hypersensitivity to it. It is also not recommended for patients who have had asthma, hives, or other allergic reactions after taking Aspirin or other NSAIDs.
Pregnancy & Breastfeeding
Pregnancy & Breastfeeding: There haven't been enough well-controlled studies looking at Etodolac's safety in pregnant women, so it should only be used during pregnancy if the potential benefit to the mother is thought to outweigh the possible risk to the unborn baby. It also isn't known whether Etodolac passes into breast milk, so a nursing mother and her doctor should weigh how important the medicine is to her health when deciding whether to continue breastfeeding or continue the treatment.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
After an acute overdose of an NSAID like etodolac, the symptoms are usually limited to lethargy, drowsiness, nausea, vomiting and epigastric pain. These generally clear up with supportive care.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Etodolac at a temperature not above 30°C. Keep it away from light, and keep it out of the reach of children.
Drug Interactions
Common questions about Edac 600 mg
What is Edac 600 mg Tablet?
Edac 600 mg Tablet is a medicine that contains Etodolac. It is made by Delta Pharma PLC. It belongs to the Drugs for Osteoarthritis group of medicines.
What is Edac used for?
Edac is used for: Pain, Osteoarthritis, Rheumatoid Arthritis, Gout.
What are the side effects of Edac?
Panodin SR mainly affects the digestive system. It may cause stomach pain, constipation, diarrhea, indigestion, gas, heartburn, nausea, vomiting, and stomach or intestinal ulcers.
Can I take Edac during pregnancy or while breastfeeding?
Pregnancy & Breastfeeding: There haven't been enough well-controlled studies looking at Etodolac's safety in pregnant women, so it should only be used during pregnancy if the potential benefit to the mother is thought to outweigh the possible risk to the unborn baby. It also isn't known whether Etodolac passes into breast milk, so a nursing mother and her doctor should weigh how important the medicine is to her health when deciding whether to continue breastfeeding or continue the treatment. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Edac?
After an acute overdose of an NSAID like etodolac, the symptoms are usually limited to lethargy, drowsiness, nausea, vomiting and epigastric pain. These generally clear up with supportive care. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Edac?
Store Etodolac at a temperature not above 30°C. Keep it away from light, and keep it out of the reach of children.
Can I take other medicines with Edac?
Some medicines can interact with Etodolac, for example: Polymyxin B Sulfate, Aspirin. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Edac?
Edac is a prescription (Rx) medicine. Take it as your doctor advises.