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Indications & Uses
Eczacort is indicated for:
Pharmacology
Topical corticosteroids like hydrocortisone butyrate reduce inflammation and itching, and they narrow the blood vessels. They are thought to work by inducing a group of proteins that block phospholipase A2, known together as lipocortins. These proteins are believed to control how the body makes strong inflammatory mediators such as prostaglandins and leukotrienes. They do this by stopping the release of arachidonic acid, the common precursor of both. Arachidonic acid is released from membrane phospholipids by phospholipase A2.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
For adults with corticosteroid-responsive dermatoses, apply a thin film of hydrocortisone butyrate to the affected skin two or three times a day, depending on how severe the condition is, and rub it in gently. For atopic dermatitis in patients aged 3 months to 18 years, apply a thin film to the affected skin two times a day and rub it in gently. Don't apply hydrocortisone butyrate in the diaper area unless a physician has directed it.
Stop the treatment once the condition is under control. If there is no improvement within 2 weeks, the diagnosis may need to be reassessed. Before prescribing for more than 2 weeks, the doctor should weigh any extra benefit of extending treatment to 4 weeks against the risk of HPA axis suppression and local adverse events. The safety and efficacy of hydrocortisone butyrate have not been established beyond 4 weeks of use.
Don't use hydrocortisone butyrate with occlusive dressings unless a physician has directed it. Avoid use in the diaper area, because diapers or plastic pants may act as occlusive dressings.
Pediatric use: Safety and efficacy in pediatric patients below 3 months of age have not been established.
Geriatric use: Safety and efficacy in geriatric patients over 65 years of age have not been established.
Side Effects
When hydrocortisone butyrate is first put on the skin, you may notice stinging, burning, itching, irritation, dryness or redness at the spot where it was applied. These effects should go away in a few days as the body gets used to the medicine.
Cautions & Contraindications
Warnings & Precautions
Systemic absorption of topical corticosteroids such as Hydrocortisone Butyrate has caused reversible hypothalamic-pituitary-adrenal (HPA) axis suppression in some patients. Manifestations of Cushing's syndrome, hyperglycemia and glucosuria have also been seen. Absorption goes up when a more potent corticosteroid is applied, when it is used over large surface areas, when it is used for a long time, and when occlusive dressings are added. Children may absorb proportionally larger amounts of topical corticosteroids, so they are more likely to suffer systemic toxicity. If irritation develops, stop the corticosteroid and start appropriate treatment. If there is a skin infection, start an appropriate antifungal or antibacterial agent. And if the skin doesn't respond promptly, stop the corticosteroid until the infection has been adequately controlled.
Contraindications
Don't use Hydrocortisone Butyrate if you have ever had a sensitivity reaction to any of its active ingredients.
Pregnancy & Breastfeeding
Pregnancy: No adequate and well-controlled studies have been done in pregnant women. So Hydrocortisone Butyrate should be used in pregnancy only if the possible benefit justifies the possible risk to the fetus. Corticosteroids given systemically at relatively low doses have been shown to be teratogenic in laboratory animals, and some corticosteroids have also been shown to be teratogenic in laboratory animals after application to the skin.
Lactation: It is not known whether topical corticosteroids can be absorbed into the body in large enough amounts to appear in breast milk in detectable quantities. Corticosteroids given systemically are secreted into breast milk, but not in quantities likely to harm the infant. Even so, caution should be exercised when a topical corticosteroid is given to a nursing woman.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Hydrocortisone Butyrate below 25°C. Keep it away from light, don't freeze it, and keep it out of reach of children.
Common questions about Eczacort 0.1%
What is Eczacort 0.1% Cream?
Eczacort 0.1% Cream is a medicine that contains Hydrocortisone Butyrate. It is made by Ziska Pharmaceuticals Ltd.
What is Eczacort used for?
Eczacort is used for: Eczema.
What are the side effects of Eczacort?
When hydrocortisone butyrate is first put on the skin, you may notice stinging, burning, itching, irritation, dryness or redness at the spot where it was applied. These effects should go away in a few days as the body gets used to the medicine.
Can I take Eczacort during pregnancy or while breastfeeding?
Pregnancy: No adequate and well-controlled studies have been done in pregnant women. So Hydrocortisone Butyrate should be used in pregnancy only if the possible benefit justifies the possible risk to the fetus. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Eczacort?
Store Hydrocortisone Butyrate below 25°C. Keep it away from light, don't freeze it, and keep it out of reach of children.
Do I need a prescription for Eczacort?
Eczacort is a prescription (Rx) medicine. Take it as your doctor advises.