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Same active ingredient — pay up to 25% less
These brands contain the same active ingredient (Dydrogesterone). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Dydron is indicated for:
Pharmacology
Dydrogesterone is an orally active progestogen. In an estrogen-primed uterus, it brings the endometrium to a full secretory state, which guards against the endometrial hyperplasia and malignant change that estrogen alone can cause. It is used in all forms of endogenous progesterone deficiency. It carries no estrogenic, androgenic, thermogenic, anabolic, or corticoid activity.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Progesterone deficiencies
Threatened miscarriage: 40 mg (four tablets) at once, then 10 mg (one tablet) every eight hours until symptoms settle. Habitual miscarriage: 10 mg (one tablet) twice daily until the twentieth week of pregnancy. Dysmenorrhoea: 10 mg (one tablet) twice daily from day 5 to day 25 of the menstrual cycle. Endometriosis: 10 mg (one tablet) two or three times daily from day 5 to day 25 of the cycle, or continuously.
Dysfunctional bleeding (to arrest bleeding): 10 mg (one tablet) twice daily for five to seven days. Presentation should be given with oestrogen. Dysfunctional bleeding (to prevent bleeding): 10 mg (one tablet) twice daily from day 11 to day 25 of the cycle, again with oestrogen.
Amenorrhoea: an oestrogen once daily from day 1 to day 25 of the cycle, together with 10 mg Presentation twice daily from day 11 to day 25 of the cycle. Irregular cycles: 10 mg (one tablet) twice daily from day 11 to day 25 of the cycle.
Infertility due to luteal insufficiency: 10 mg (one tablet) daily from day 14 to day 25 of the cycle. The treatment should run for at least 6 consecutive cycles. Many doctors advise carrying on through the first month of any pregnancy, using the doses given for habitual miscarriage.
Luteal support as part of an Assisted Reproductive Technology (ART) treatment: 10 mg three times daily (three tablets daily), starting on the day of oocyte retrieval and continuing for 10 weeks if pregnancy is confirmed.
Hormone Replacement Therapy: with continuous oestrogen therapy, take one tablet daily for 14 consecutive days of a 28 day cycle. With cyclical oestrogen therapy, take one tablet daily during the last 12 to 14 days of oestrogen therapy.
For doctors: if endometrial biopsies or ultrasound show an inadequate Presentationational response, a 20 mg Dydrogesterone dose should be prescribed.
For patients: if you are not sure which type of oestrogen therapy you are on, speak to your doctor before taking Presentation.
There is no relevant use of Dydrogesterone before menarche. The safety and efficacy of Dydrogesterone in adolescents aged 12 to 18 years has not been established.
Side Effects
The most commonly reported side effects in patients taking Caryon during clinical trials for indications not involving oestrogen treatment include migraines/headaches, nausea, menstrual disorders, and breast pain or tenderness.
Cautions & Contraindications
Warnings & Precautions
Before starting Caryon for abnormal bleeding, the cause of the bleeding should be clarified first. Breakthrough bleeding and spotting may occur during the first few months of treatment. If breakthrough bleeding or spotting shows up after some time on therapy, or continues after treatment has been stopped, the reason should be investigated, which may include an endometrial biopsy to rule out endometrial malignancy. If any of the following conditions occurs for the first time or worsens during use, stopping treatment should be considered: severe headache or migraine, or symptoms suggesting cerebral ischemia; a marked rise in blood pressure; or the occurrence of venous thromboembolism (VTE). In cases of habitual or threatened miscarriage, the viability of the fetus should be confirmed, and it is also necessary to monitor during treatment whether the pregnancy is still progressing and whether the embryo remains alive. Treatment with Caryon has occasionally been associated with changes in liver function, sometimes with accompanying clinical symptoms, so it should be used with caution in patients with acute liver disease or a history of liver disease until liver function tests return to normal, and in cases of severe hepatic impairment, treatment should be stopped. Patients with a history of depression should be monitored closely, and if severe depression returns, treatment with Caryon should be discontinued.
Contraindications
Hypersensitivity to the active substance or to any of the excipients. Known or suspected progestogen-dependent tumours. Unexplained vaginal bleeding of undiagnosed cause. Use for preventing endometrial hyperplasia in women taking oestrogen therapy. Thrombophlebitis or other thromboembolic disorders. Cerebrovascular or coronary artery disease, whether current or a past history of these. Liver disease or impaired liver function, including a history of cholestatic jaundice, pruritus of pregnancy, Dubin-Johnson syndrome, or Rotor syndrome. A history of herpes occurring during pregnancy. Sickle cell anaemia. Benign or malignant liver tumours that developed during previous use of oral contraceptives.
Pregnancy & Breastfeeding
Dydrogesterone has not so far been linked to any harmful effects when used during pregnancy. It does, however, pass into breast milk, and because a risk to the nursing infant cannot be ruled out, it should not be used while breast-feeding. As for fertility, there is no evidence that Dydrogesterone reduces it.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Dydrogesterone was well tolerated when taken by mouth, even at the maximum daily dose of 360 mg. No ill effects from overdose have been reported. If a large overdose is found within two or three hours and treatment seems necessary, gastric lavage is recommended. There is no specific antidote, so treatment should be based on the symptoms. The same applies to overdose in children.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Dydrogesterone below 30°C, in a dry place and away from light. Keep it out of reach of children.
Common questions about Dydron 10 mg
What is Dydron 10 mg Tablet?
Dydron 10 mg Tablet is a medicine that contains Dydrogesterone. It is made by Nuvista Pharma PLC. It belongs to the Female Sex hormones group of medicines.
What is Dydron used for?
Dydron is used for: Menstrual Disorder.
What are the side effects of Dydron?
The most commonly reported side effects in patients taking Caryon during clinical trials for indications not involving oestrogen treatment include migraines/headaches, nausea, menstrual disorders, and breast pain or tenderness.
Can I take Dydron during pregnancy or while breastfeeding?
Dydrogesterone has not so far been linked to any harmful effects when used during pregnancy. It does, however, pass into breast milk, and because a risk to the nursing infant cannot be ruled out, it should not be used while breast-feeding. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Dydron?
Dydrogesterone was well tolerated when taken by mouth, even at the maximum daily dose of 360 mg. No ill effects from overdose have been reported. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Dydron?
Keep Dydrogesterone below 30°C, in a dry place and away from light. Keep it out of reach of children.
Is there a cheaper medicine with the same ingredient?
Progency by Healthcare Pharmaceuticals Ltd. has the same ingredient and strength for ৳30.00 per unit, compared with ৳40.00 for Dydron. Ask your doctor or pharmacist before switching.
Do I need a prescription for Dydron?
Dydron is a prescription (Rx) medicine. Take it as your doctor advises.