Pricing
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All price changes →Indications & Uses
Durabolin is indicated for:
Pharmacology
Nandrolone Phenylpropionate is an injectable anabolic preparation. The active substance is nandrolone, and the phenylpropionate ester makes one injection last about one week. Nandrolone is chemically related to the male hormone. Compared with testosterone, its anabolic activity is greater and its androgenic activity is lower. Animal bioassays showed this, and receptor binding studies explain it. Clinical use also confirms that nandrolone has low androgenicity. In humans, it has a nitrogen saving action. Metabolic studies established this effect on protein metabolism, and it is used in treatment where a protein deficiency exists, such as during chronic debilitating diseases and after major surgery and severe trauma. In these conditions, Nandrolone Phenylpropionate is a supportive adjunct to specific therapies and dietary measures. In women with disseminated mammary carcinoma, objective regressions lasting many months have been reported in selected cases. It has also been shown to relieve bone pain in patients with osteoporosis. Nandrolone decanoate, a nandrolone ester that acts in a similar way, has been shown to increase bone mineral content in these patients. Androgenic effects (e.g. virilisation) are relatively uncommon at the recommended dosages. Nandrolone lacks the C17alpha-alkyl group, which is associated with liver dysfunction and cholestasis.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Nandrolone Phenylpropionate is used as an adjunct to specific therapies and dietary measures in conditions marked by a negative nitrogen balance, and the recommended dose is 25 to 50 mg every week. For the palliative treatment of selected cases of disseminated mammary carcinoma in women, the recommended dose is 50 mg every week. In osteoporosis the recommended dose is also 50 mg every week. To get the best therapeutic effect, the person needs adequate amounts of vitamins, minerals and protein in a calorie-rich diet. Nandrolone Phenylpropionate should be given by deep intramuscular injection.
Side Effects
High doses, long treatment or giving Nandrolone Phenylpropionate too often may cause virilisation. Sensitive women may notice hoarseness, acne, hirsutism and an increase of libido. Prepubertal boys may have more frequent erections and phallic enlargement, while girls may develop an increase of pubic hair and clitoral hypertrophy. Hoarseness can be the first sign of a change in the voice. The change may end as a long-lasting deepening of the voice, and sometimes it is irreversible. Other effects are amenorrhoea, inhibition of spermatogenesis, premature epiphyseal closure and fluid retention.
Cautions & Contraindications
Warnings & Precautions
If signs of virilisation develop, think about stopping Nandrolone Phenylpropionate, and preferably talk it over with the patient first. Patients with any of the following conditions, or a history of them, should be monitored. These are latent or overt cardiac failure, renal dysfunction, hypertension and migraine, because anabolic steroids may occasionally cause fluid retention. Monitoring is also advised in incomplete statural growth, since high doses of anabolic steroids may speed up epiphyseal closure. The same applies to skeletal metastases of breast carcinoma. In these patients hypercalcaemia may develop on its own and also as a result of anabolic steroid therapy. The latter can point to a positive tumour response to the hormonal treatment. Even so, the hypercalcaemia should be treated properly first, and once calcium levels are back to normal, hormone therapy can be resumed. Liver dysfunction is another condition where monitoring is advised. Using anabolic steroids to improve athletic ability may carry severe risks to the user's health and should be discouraged.
Contraindications
Nandrolone Phenylpropionate must not be used in pregnancy, or in men with known or suspected carcinoma of the prostate or breast.
Pregnancy & Breastfeeding
Nandrolone Phenylpropionate must not be used during pregnancy, because it can cause masculinization of the foetus. For breastfeeding, there isn't enough data to say whether the medicine could harm the infant or affect milk production.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Nandrolone Phenylpropionate has very low acute toxicity in animals. No cases of acute overdosage with Nandrolone Phenylpropionate have been reported in humans.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Nandrolone Phenylpropionate below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Durabolin 25 mg/ml
What is Durabolin 25 mg/ml IM Injection?
Durabolin 25 mg/ml IM Injection is a medicine that contains Nandrolone Phenylpropionate. It is made by Nuvista Pharma PLC. It belongs to the Anabolic steroid (Androgens) group of medicines.
What is Durabolin used for?
Durabolin is used for: Osteoporosis, Cancer.
What are the side effects of Durabolin?
High doses, long treatment or giving Nandrolone Phenylpropionate too often may cause virilisation. Sensitive women may notice hoarseness, acne, hirsutism and an increase of libido.
Can I take Durabolin during pregnancy or while breastfeeding?
Nandrolone Phenylpropionate must not be used during pregnancy, because it can cause masculinization of the foetus. For breastfeeding, there isn't enough data to say whether the medicine could harm the infant or affect milk production. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Durabolin?
Nandrolone Phenylpropionate has very low acute toxicity in animals. No cases of acute overdosage with Nandrolone Phenylpropionate have been reported in humans. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Durabolin?
Store Nandrolone Phenylpropionate below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Durabolin?
Some medicines can interact with Nandrolone Phenylpropionate, for example: Insulin (Human) 30/70. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Durabolin?
Durabolin is a prescription (Rx) medicine. Take it as your doctor advises.