Indications & Uses
DLP 60 is indicated for:
Pharmacology
Dexlansoprazole delayed-release capsule belongs to a class of medicines called proton pump inhibitors (PPIs). It reduces the amount of acid made by the stomach by specifically blocking the (H+/K+)-ATPase pump in the acid-producing cells of the stomach lining. Since this pump carries out the last step of acid production, targeting it directly shuts down acid release at its source.
Dexlansoprazole is the R-enantiomer of lansoprazole, which itself is a racemic mixture of R- and S-enantiomers. It is formulated as a Dual Delayed Release (DDR) capsule for oral use, containing two types of enteric-coated granules that dissolve at different pH levels. This design produces two separate absorption peaks in the blood: the first occurs 1 to 2 hours after taking the dose, and the second follows 4 to 5 hours after. After the medicine is taken by mouth, its peak blood concentration (Cmax) and overall exposure (AUC) rise roughly in proportion to the dose given. Dexlansoprazole is broken down mainly by the liver and leaves the body through urine.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dexlansoprazole dosing recommendations: for maintenance of healed erosive esophagitis and relief of heartburn, the dose is 30 mg once daily. For symptomatic non-erosive GERD, the dose is 30 mg once daily for 4 weeks. For healing of erosive esophagitis, the dose is 60 mg once daily for up to 8 weeks.
Dexlansoprazole MUPS dosing recommendations: for maintenance of healed erosive esophagitis and relief of heartburn, the dose is one 30 mg tablet once daily, taken for 6 months in adults and for 16 weeks in patients 12 to 17 years of age. For symptomatic non-erosive GERD, the dose is one 30 mg tablet once daily for 4 weeks.
Side Effects
Common side effects may include diarrhea, stomach pain, nausea, vomiting, and gas.
Cautions & Contraindications
Warnings & Precautions
Take care with Dexall (dexlansoprazole) in these situations: gastric malignancy, Clostridium difficile associated diarrhea, bone fracture and hypomagnesemia. Care is also needed when Dexall is used together with methotrexate.
Contraindications
Dexlansoprazole should not be used by anyone known to be hypersensitive to it or to any of the ingredients in its formulation.
Pregnancy & Breastfeeding
Pregnancy Category B. No adequate and well-controlled studies have looked at Dexlansoprazole's use in pregnant women, and the same is true for lactating mothers.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Children and adolescents: The safety and effectiveness of DDR haven't been established in patients below 12 years of age.
Geriatric use: Elderly patients don't need a dose adjustment.
Renal impairment: Patients with renal impairment don't need a dose adjustment of DDR.
Hepatic impairment: Patients with mild hepatic impairment don't need a dose adjustment of DDR. For patients with moderate hepatic impairment, a maximum daily dose of DDR 30 mg should be considered.
Overdose
No significant overdose of dexlansoprazole delayed release (DDR) has been reported. People have taken multiple doses of DDR 120 mg and a single dose of DDR 300 mg, and none of them died or had other severe adverse events.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Dexlansoprazole below 30°C, in a dry place and away from light. Keep all medicines out of reach of children.
Drug Interactions
Common questions about DLP 60 60 mg
What is DLP 60 60 mg Capsule?
DLP 60 60 mg Capsule is a medicine that contains Dexlansoprazole. It is made by General Pharmaceuticals Ltd. It belongs to the Proton Pump Inhibitor group of medicines.
What is DLP 60 used for?
DLP 60 is used for: Gastroesophageal Reflux Disease.
What are the side effects of DLP 60?
Common side effects may include diarrhea, stomach pain, nausea, vomiting, and gas.
Can I take DLP 60 during pregnancy or while breastfeeding?
Pregnancy Category B. No adequate and well-controlled studies have looked at Dexlansoprazole's use in pregnant women, and the same is true for lactating mothers. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much DLP 60?
No significant overdose of dexlansoprazole delayed release (DDR) has been reported. People have taken multiple doses of DDR 120 mg and a single dose of DDR 300 mg, and none of them died or had other severe adverse events. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store DLP 60?
Keep Dexlansoprazole below 30°C, in a dry place and away from light. Keep all medicines out of reach of children.
Can I take other medicines with DLP 60?
Some medicines can interact with Dexlansoprazole, for example: Methotrexate, Clopidogrel, Tacrolimus, Atazanavir, Warfarin Sodium. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for DLP 60?
DLP 60 is a prescription (Rx) medicine. Take it as your doctor advises.