DK

Phylloquinone, often called vitamin K1, is fat soluble and stable in air and moisture, but it breaks down in sunlight. It is found naturally in many green plants. The body needs vitamin K for the post translational modification of certain proteins, mostly those required for blood coagulation.

Vitamin K2 is necessary for the activation of osteocalcin, a protein that carries calcium into bone and builds it into the bone, which keeps the skeleton healthy. When calcium goes into the bone matrix, less of it is left to form harmful deposits in soft body tissues.

Vitamin D3 (Cholecalciferol) is essential for normal bone growth and development and for keeping bone density. It also helps the body use both calcium and phosphorus. The active form of vitamin D3, Calcitriol, works by binding to the Vitamin D receptors (VDRs), which are spread widely through many body tissues. Because vitamin D3 is fat soluble, its half life is about 50 days.

Vitamin D3 is absorbed in the small intestine, where it binds to specific a-globulins and is carried to the liver. There it is metabolised to 25-hydroxy Vitamin D3 (Calcidiol). A second hydroxylation to 1,25-dihydroxy Vitamin D3 (Calcitriol) takes place in the kidney, and this metabolite is what lets the vitamin increase calcium absorption. Vitamin D3 that has not been metabolised is stored in tissues such as fat and muscle. It is eliminated through faeces and urine.

Vitamin K & D3 is safe to use in pregnancy and while breastfeeding, as long as it is taken in the recommended doses.

Keep this medicine in a cool, dry place below 30°C. Protect it from direct sunlight and moisture, and don't freeze it.