Pricing
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Dextrim is indicated for:
Pharmacology
This preparation combines three medicines: a cough suppressant, a decongestant and an antihistamine. Dextromethorphan is a safe and effective non-narcotic cough suppressant. It acts on the cough centre in the medulla, which is in the brain. It is structurally related to Morphine, but it has no pain-relieving effect and is not habit forming, and in general it causes little sedation.
Phenylephrine is a decongestant. It shrinks the blood vessels in the nasal passage, and it is used to treat nasal and sinus congestion of the tubes that drain fluid from the inner ear.
Triprolidine gives symptomatic relief in conditions believed to depend wholly or partly on the triggered release of histamine. It is a potent competitive histamine H1-receptor antagonist of the pyrrolidine class. It also has mild central nervous system depressant properties, which may cause drowsiness.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
For adults and children aged 12 years and older, the usual dose of Dextromethorphan + Phenylephrine + Triprolidine is 1 teaspoonful (5 ml) every 4 hours, or as directed by a doctor. Children aged 6 to under 12 years can take ½ teaspoonful (2.5 ml) every 4 hours, or as directed by a doctor.
For children aged 2 to 6 years, use it with caution and only as the physician advises. Don't give it to children below 2 years old.
Side Effects
Dextromethorphan + Phenylephrine + Triprolidine can cause drowsiness, dottiness and constipation. Discomfort in the gut (GIT) may also occur. There is no apparent evidence of physical dependence of the morphine type. Less common side effects include transient hypertension, dry mouth, restlessness and palpitations. Some people get allergic reactions such as rashes, or tightness of chest. Thickening of bronchial secretions, toxic psychosis and blood dyscrasia may also occur.
Cautions & Contraindications
Warnings & Precautions
Dextromethorphan + Phenylephrine + Triprolidine may make you drowsy. If you feel drowsy, don't drive or operate machinery. Avoid alcohol while you are taking this medicine. Use it with caution if you have epilepsy, prostatic hypertrophy, glaucoma, liver disease, high blood pressure, heart disease, diabetes or hyperthyroidism. The same applies to stenosing peptic ulcer, pyloro-duodenal obstruction and bladder neck obstruction. In all of these conditions, use it only under medical advice and supervision. If your symptoms don't improve within one week, or if they come with a high fever, see a physician before you continue using it.
Contraindications
Patients with liver disease or asthma should avoid this combination of dextromethorphan, phenylephrine and triprolidine. It must not be given during an acute attack of asthma. It is also contraindicated in people taking monoamine oxidase inhibitors, or within 2 weeks of stopping such treatment, and in anyone with known hypersensitivity to phenylephrine hydrochloride or dextromethorphan hydrobromide. People with severe hypertension or severe coronary artery disease must not take it either.
Overdose
If someone takes too much of this medicine, admission to hospital is strongly advised. An overdose may cause respiratory depression, paranoid psychosis, delusions, hallucinations and convulsion. Treatment should include emptying the stomach by aspiration or gastric lavage. Nervous stimulation and convulsions should be treated with a sedative such as diazepam given intramuscularly. If marked excitation is present, a sedative such as diazepam or a short-acting barbiturate may be given.
A severe overdose of phenylephrine hydrochloride may produce hypertension, along with reflex bradycardia. Treatment includes early gastric lavage and symptomatic and supportive measures. The hypertensive effects may be treated with an alpha-receptor blocking agent (such as phentolamine mesilate 6 to 10 mg) given intravenously. The bradycardia is treated with atropine, preferably only after the blood pressure has been controlled.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep this medicine out of the reach of children. Store it in a cool, dry place and protect it from light.
Drug Interactions
Common questions about Dextrim 20 mg+10 mg+2.5 mg
What is Dextrim 20 mg+10 mg+2.5 mg Syrup?
Dextrim 20 mg+10 mg+2.5 mg Syrup is a medicine that contains Dextromethorphan + Phenylephrine + Triprolidine. It is made by Beximco Pharmaceuticals Ltd. It belongs to the Combined cough suppressants group of medicines.
What is Dextrim used for?
Dextrim is used for: Allergic Rhinitis, Cough, Fever, Urticaria.
What are the side effects of Dextrim?
Dextromethorphan + Phenylephrine + Triprolidine can cause drowsiness, dottiness and constipation. Discomfort in the gut (GIT) may also occur.
What happens if I take too much Dextrim?
If someone takes too much of this medicine, admission to hospital is strongly advised. An overdose may cause respiratory depression, paranoid psychosis, delusions, hallucinations and convulsion. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Dextrim?
Keep this medicine out of the reach of children. Store it in a cool, dry place and protect it from light.
Can I take other medicines with Dextrim?
Some medicines can interact with Dextromethorphan + Phenylephrine + Triprolidine, for example: Rasagiline, Selegiline Hydrochloride, Atenolol, Carbamazepine, Halothane, Risperidone. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Dextrim?
Dextrim is a prescription (Rx) medicine. Take it as your doctor advises.