More from Delentin
Other strengths and forms by Renata PLC
Indications & Uses
Delentin is used to treat infections caused by roundworm (Ascaris lumbricoides), pinworm (Enterobius vermicularis), hookworm (Ancylostoma duodenale and Necator americanus), and Trichostrongylus. It can be given to both adults and children, whether one of these parasites is present or several occur together.
Pharmacology
Pyrantel pamoate works by causing a sudden, spastic contraction of the worm's muscles that then locks into paralysis. This makes the worm release its grip on the intestinal wall, so it is simply carried out of the body in the stool through the gut's normal movements. Because very little of the drug crosses into the bloodstream from the intestine, the small doses used do not go on to affect the person taking it.
That said, spastic paralyzing agents like pyrantel pamoate can, in a heavy worm infestation, cause a complete intestinal blockage. This tends to happen as a worm impaction, when a small body with a very high worm burden is treated and has to pass a large number of dislodged worms all at once. Usually, though, the worms simply pass in the stool or with some diarrhea, straining, and occasionally vomiting.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Pyrantel Pamoate can be taken by mouth at any time, with or without food. The usual approach is a single dose of 11 mg/kg body weight, up to a maximum of 1 g, to treat the infestations noted above. For Pinworm infection, it is often advisable to repeat this dose after 2 weeks.
Side Effects
Delentin is well tolerated at the recommended dosage. At higher doses, it may cause gastrointestinal upset such as loss of appetite, nausea, vomiting and diarrhoea. Less commonly, some people experience headache, dizziness or rash.
Cautions & Contraindications
Warnings & Precautions
Since Delentin and Piperazine tend to work against each other, they should not be taken at the same time. Keep Delentin out of children's reach.
Contraindications
Contraindicated in patients with known hypersensitivity to pyrantel or to any other ingredient in the formulation.
Pregnancy & Breastfeeding
Pregnancy: There is no established safety data for Pyrantel Pamoate use during pregnancy, so it is generally not advised for pregnant patients. It is also not recommended for children under 1 year of age.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Pediatric Use
Safety and efficacy of Pyrantel Pamoate have not been established in children under 2 years of age. In this age group, give it only when the possible benefits justify the possible risks.
Hepatic Impairment
Use Pyrantel Pamoate with caution in patients who already have liver dysfunction (hepatic impairment).
Storage
Store Pyrantel Pamoate below 30°C, away from light and moisture. Keep it out of the reach of children.
Common questions about Delentin 125 mg
What is Delentin 125 mg Tablet?
Delentin 125 mg Tablet is a medicine that contains Pyrantel Pamoate. It is made by Renata PLC. It belongs to the Anthelmintic group of medicines.
What is Delentin used for?
Delentin is used to treat infections caused by roundworm (Ascaris lumbricoides), pinworm (Enterobius vermicularis), hookworm (Ancylostoma duodenale and Necator americanus), and Trichostrongylus. It can be given to both adults and children, whether one of these parasites is present or several occur together.
What are the side effects of Delentin?
Delentin is well tolerated at the recommended dosage. At higher doses, it may cause gastrointestinal upset such as loss of appetite, nausea, vomiting and diarrhoea.
Can I take Delentin during pregnancy or while breastfeeding?
Pregnancy: There is no established safety data for Pyrantel Pamoate use during pregnancy, so it is generally not advised for pregnant patients. It is also not recommended for children under 1 year of age. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Delentin?
Store Pyrantel Pamoate below 30°C, away from light and moisture. Keep it out of the reach of children.
Do I need a prescription for Delentin?
Delentin is a prescription (Rx) medicine. Take it as your doctor advises.