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Indications & Uses
Dextromethorphan + Pseudoephedrine + Triprolidine gives temporary relief from symptoms caused by the common cold, hay fever (allergic rhinitis) or other upper respiratory allergies. These symptoms are non-productive cough due to minor throat or bronchial irritation, runny nose, sneezing, itching of the nose or throat, itchy and watery eyes, and nasal congestion.
Pharmacology
This combination of dextromethorphan, pseudoephedrine and triprolidine brings together a cough suppressant, a decongestant and an antihistamine. Dextromethorphan is a safe and effective non-narcotic cough suppressant. It acts centrally, on the cough centre in the medulla. It is structurally related to morphine, but it has no ppainkilling or habit-forming properties, and in general it has little sedative activity.
Phenylephrine is a decongestant that shrinks the blood vessels in the nasal passage. It is used for temporary relief of a stuffy nose and of sinus and ear symptoms caused by the common cold, flu, allergies, sinusitis and bronchitis. It works by reducing swelling in the nose and ears, which eases discomfort and makes breathing easier.
Triprolidine is an antihistamine used to relieve symptoms of allergy, hay fever and the common cold. These symptoms include rash, watery eyes, itchy eyes, nose, throat and skin, cough, runny nose and sneezing. It is a potent competitive histamine H1-receptor antagonist of the pyrrolidine class, with mild central nervous system depressant properties that may cause drowsiness. It also blocks another natural substance, acetylcholine, and this helps dry up some body fluids, so symptoms such as watery eyes and a runny nose settle.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and children over 12 years can take 1 teaspoonful (5 ml) four times a day, with 4 hours between doses. For children aged 6 to 12 years, the dose is 1/2 teaspoonful four times a day, again with 4 hours between doses.
For children under 6 years, get a physician's advice before giving this combination of Dextromethorphan, Pseudoephedrine and Triprolidine.
Side Effects
This combination of dextromethorphan, pseudoephedrine and triprolidine can cause drowsiness and constipation. Some people may also have GIT discomfort. There is no clear evidence of physical dependence of the morphine type with it.
Cautions & Contraindications
Warnings & Precautions
Dextromethorphan + Pseudoephedrine + Triprolidine can make you drowsy. If you feel drowsy, don't drive a motor vehicle or operate machinery. Avoid alcoholic drink while you are taking this medicine. Use it with caution if you have epilepsy, prostatic hypertrophy, glaucoma, hepatic disease, hypertension, heart disease, diabetes or hyperthyroidism. If your symptoms don't improve within one week, or if you also have a high fever, consult a physician before you continue using it.
Contraindications
Patients with liver disease or asthma should avoid this combination of dextromethorphan, pseudoephedrine and triprolidine. It must not be given to anyone taking monoamine oxidase inhibitors, or to anyone who stopped such treatment within the last 2 weeks.
Overdose
If someone takes too much of this medicine (dextromethorphan with pseudoephedrine and triprolidine), they should be admitted to hospital, and this is strongly advised. An overdose may cause respiratory depression, paranoid psychosis, delusions, hallucinations and convulsion.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep this medicine in a cool, dry place where the temperature stays below 30°C, and away from light. Always keep it out of the reach of children.
Drug Interactions
Common questions about Decoff 10 mg+30 mg+1.25 mg
What is Decoff 10 mg+30 mg+1.25 mg Syrup?
Decoff 10 mg+30 mg+1.25 mg Syrup is a medicine that contains Dextromethorphan + Pseudoephedrine + Triprolidine. It is made by Hudson Pharmaceuticals Ltd. It belongs to the Combined cough suppressants group of medicines.
What is Decoff used for?
Dextromethorphan + Pseudoephedrine + Triprolidine gives temporary relief from symptoms caused by the common cold, hay fever (allergic rhinitis) or other upper respiratory allergies. These symptoms are non-productive cough due to minor throat or bronchial irritation, runny nose, sneezing, itching of the nose or throat, itchy and watery eyes, and nasal congestion.
What are the side effects of Decoff?
This combination of dextromethorphan, pseudoephedrine and triprolidine can cause drowsiness and constipation. Some people may also have GIT discomfort.
What happens if I take too much Decoff?
If someone takes too much of this medicine (dextromethorphan with pseudoephedrine and triprolidine), they should be admitted to hospital, and this is strongly advised. An overdose may cause respiratory depression, paranoid psychosis, delusions, hallucinations and convulsion. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Decoff?
Keep this medicine in a cool, dry place where the temperature stays below 30°C, and away from light. Always keep it out of the reach of children.
Can I take other medicines with Decoff?
Some medicines can interact with Dextromethorphan + Pseudoephedrine + Triprolidine, for example: Selegiline Hydrochloride, Rasagiline. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Decoff?
Decoff is a prescription (Rx) medicine. Take it as your doctor advises.