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Other brands with the same active ingredient
These brands contain the same active ingredient (Glibenclamide). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Daosin is indicated for:
Pharmacology
Glibenclamide appears to lower blood glucose in the short term by stimulating the pancreas to release insulin, an effect that depends on the beta cells in the pancreatic islets still functioning. How it lowers blood glucose with long-term use is not clearly understood. In Type 2 diabetes patients on chronic therapy, the blood-glucose-lowering effect continues even as the drug's ability to trigger insulin secretion gradually declines. Besides lowering blood glucose, Glibenclamide also produces a mild diuretic effect by increasing the kidneys' free water clearance.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
There is no single fixed dosage schedule for treating diabetes mellitus with Glibenclamide or with any other hypoglycemic medicine. As initial therapy, the usual starting dose is 2.5 to 5 mg daily, taken with breakfast or the first main meal of the day. Those patients who may be more sensitive to hypoglycemic drugs should begin at a lower dose of 1.25 mg daily. The usual maintenance dose falls in the range of 1.25 to 20 mg daily, and this may be taken as a single dose or split into divided doses. Any increase in dosage should be made in steps of no more than 2.5 mg, spaced at least a week apart, guided by the patient's blood glucose response. Daily doses above 20 mg are not recommended.
Side Effects
Severe hypoglycemic reactions involving coma, seizure, or other neurological impairment occur infrequently.
Cautions & Contraindications
Warnings & Precautions
All sulfonylureas, including glibenclamide, can cause severe hypoglycaemia (low blood sugar). To reduce the risk of hypoglycaemic episodes, it is important to select suitable patients, use the correct dose, and give clear instructions.
Contraindications
Glibenclamide should not be used by people who are known to be allergic to the drug or to any of its other ingredients. It is also not suitable for people with type 1 diabetes or for those who have diabetic ketoacidosis, whether or not they are in a coma. Such conditions need to be treated with insulin instead.
Pregnancy & Breastfeeding
Pregnancy Category C. No specific data exist on Glibenclamide use during human pregnancy, but the medicine has been used widely for many years without any apparent harm being reported. Studies in animals have not shown any risk. Whether Glibenclamide passes into human breast milk is not yet known. Other sulphonylureas, however, do pass into breast milk, and there is no reason to think Glibenclamide behaves any differently in this regard.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Glibenclamide below 30°C, away from light and moisture. And as with all medicines, keep it out of reach of children.
Drug Interactions
Common questions about Daosin 5 mg
What is Daosin 5 mg Tablet?
Daosin 5 mg Tablet is a medicine that contains Glibenclamide. It is made by G. A. Company Ltd. It belongs to the Sulfonylureas group of medicines.
What is Daosin used for?
Daosin is used for: Type 2 Diabetes Mellitus, Diabetes Mellitus.
What are the side effects of Daosin?
Severe hypoglycemic reactions involving coma, seizure, or other neurological impairment occur infrequently.
Can I take Daosin during pregnancy or while breastfeeding?
Pregnancy Category C. No specific data exist on Glibenclamide use during human pregnancy, but the medicine has been used widely for many years without any apparent harm being reported. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Daosin?
Keep Glibenclamide below 30°C, away from light and moisture. And as with all medicines, keep it out of reach of children.
Can I take other medicines with Daosin?
Some medicines can interact with Glibenclamide, for example: Miconazole, Vildagliptin, Tenoxicam, Tamsulosin Hydrochloride + Dutasteride, Isoniazid, Chloramphenicol. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Daosin?
Daosin is a prescription (Rx) medicine. Take it as your doctor advises.