Pricing
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Crisa is indicated for:
Pharmacology
Crisaborole is a phosphodiesterase-4 (PDE-4) inhibitor. It acts mainly on phosphodiesterase 4B (PDE4B), the enzyme linked to inflammation. Chemically, Crisaborole is a phenoxybenzoxaborole, and it carries a boron atom. That boron helps the medicine penetrate the skin and is essential for its binding activity.
When PDE4B is inhibited, the release of tumor necrosis factor alpha (TNFα), interleukin-12 (IL-12), IL-23 and other cytokines appears to be suppressed. These cytokines are proteins believed to be involved in the immune response and inflammation.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Put a thin layer of Crisaborole on the affected areas twice daily. Crisaborole is for use on the skin only. Don't use it in the eyes, by mouth or in the vagina.
Side Effects
Allergic reactions Crisaborole may cause allergic reactions at or near the place where it is applied. These can be serious and may include hives, itching, swelling and redness. The most common side effect of Crisaborole is pain at the application site, such as burning or stinging.
Cautions & Contraindications
Warnings & Precautions
Some patients treated with Crisaborole have had hypersensitivity reactions, including contact urticaria. If signs or symptoms of hypersensitivity appear, stop Crisaborole immediately and start appropriate treatment.
Pregnancy & Breastfeeding
Pregnancy: No data are available on the use of Crisaborole in pregnant women, so the risk of major birth defects and miscarriage linked to the medicine is not known. In animal reproduction studies, crisaborole was given by mouth to pregnant rats and rabbits during organogenesis, at doses up to 3 and 2 times, respectively, the maximum recommended human dose (MRHD). No adverse effects on development were seen.
Lactation: There is no information on whether crisaborole passes into human milk. The medicine is absorbed into the body (systemically absorbed). Because clinical data during breastfeeding are lacking, the risk of crisaborole to a breastfed infant can't be clearly determined.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Crisaborole at a temperature not above 30°C and away from light. Keep it out of the reach of children.
Common questions about Crisa 2%
What is Crisa 2% Ointment?
Crisa 2% Ointment is a medicine that contains Crisaborole. It is made by The ACME Laboratories Ltd. It belongs to the Topical anti-inflammatory preparations group of medicines.
What is Crisa used for?
Crisa is used for: Eczema.
What are the side effects of Crisa?
Allergic reactions Crisaborole may cause allergic reactions at or near the place where it is applied. These can be serious and may include hives, itching, swelling and redness.
Can I take Crisa during pregnancy or while breastfeeding?
Pregnancy: No data are available on the use of Crisaborole in pregnant women, so the risk of major birth defects and miscarriage linked to the medicine is not known. In animal reproduction studies, crisaborole was given by mouth to pregnant rats and rabbits during organogenesis, at doses up to 3 and 2 times, respectively, the maximum recommended human dose (MRHD). Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Crisa?
Keep Crisaborole at a temperature not above 30°C and away from light. Keep it out of the reach of children.
Do I need a prescription for Crisa?
Crisa is a prescription (Rx) medicine. Take it as your doctor advises.