Indications & Uses
Contra is indicated for:
Pharmacology
Lomefloxacin is a difluorinated quinolone. It kills bacteria and acts against a broad spectrum of organisms. It interferes with bacterial DNA processes such as initiation, elongation, and termination of replication, along with transcription, DNA repair, recombination, transposition, and the supercoiling and relaxation of DNA. Its target is a subunit of the bacterial enzyme gyrase (topoisomerase II). When the drug forms a stable complex with the whole gyrase tetramer A2B2, the enzyme's function is impaired, and sensitive bacteria are killed rapidly. Plasmid mediated transfer of resistance has not been observed so far. Cross resistance has only been reported with other quinolones, not with any other class of antibiotics.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and children above 1 year of age: Instill one drop 2 times daily into the lower conjunctival sac. At the start of treatment, apply more often: either 5 drops within 20 minutes, or 1 drop every hour for 6 to 10 hours.
Side Effects
Slight, short-lived burning immediately after putting in the eye drops has been reported in 4.7% of users. Phototoxicity has not been reported with ophthalmic use, but photosensitization remains possible. The following allergic reactions have been reported after systemic use of Lomecin, so they cannot be ruled out after topical use in the eye: allergic reactions, asthma, dyspnoea, urticaria, erythema, pruritus, and hypersensitization.
Cautions & Contraindications
Warnings & Precautions
Lomecin eye drops contain Benzalkonium Chloride as a preservative, which can be absorbed into soft hydrophilic contact lenses. For this reason, soft hydrophilic contact lenses should be removed before applying Lomecin eye drops and reinserted after 15 minutes.
Contraindications
Lomefloxacin must not be used by anyone with a known hypersensitivity (allergy) to lomefloxacin or to any other ingredient of the product.
Pregnancy & Breastfeeding
Animal studies show that after systemic use, Lomefloxacin crosses the placenta and passes into breast milk. There's no clinical data on using Lomefloxacin eye drops during human pregnancy or breastfeeding. For this reason, it should be used only if the potential benefit to the pregnant or breastfeeding woman outweighs the potential risk to the fetus or infant.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Lomefloxacin in a dry place below 30°C, away from light. Once the bottle has been opened, it's best not to use the contents after one month.
Drug Interactions
Common questions about Contra 3 mg/ml
What is Contra 3 mg/ml Eye Drops?
Contra 3 mg/ml Eye Drops is a medicine that contains Lomefloxacin. It is made by Beximco Pharmaceuticals Ltd. It belongs to the 4-Quinolone preparations group of medicines.
What is Contra used for?
Contra is used for: Bacterial Infection, Conjunctivitis.
What are the side effects of Contra?
Slight, short-lived burning immediately after putting in the eye drops has been reported in 4.7% of users. Phototoxicity has not been reported with ophthalmic use, but photosensitization remains possible.
Can I take Contra during pregnancy or while breastfeeding?
Animal studies show that after systemic use, Lomefloxacin crosses the placenta and passes into breast milk. There's no clinical data on using Lomefloxacin eye drops during human pregnancy or breastfeeding. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Contra?
Keep Lomefloxacin in a dry place below 30°C, away from light. Once the bottle has been opened, it's best not to use the contents after one month.
Can I take other medicines with Contra?
Some medicines can interact with Lomefloxacin, for example: Zinc. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Contra?
Contra is a prescription (Rx) medicine. Take it as your doctor advises.