Pricing
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Other strengths and forms by Aristopharma Limited
Indications & Uses
Contine is indicated for:
Pharmacology
Theophylline is a bronchodilator belonging to the methylxanthine class of drugs. In patients with reversible airway obstruction, it works in two distinct ways: it relaxes the smooth muscle of the airways and it reduces the airways' responsiveness to irritating stimuli. It also strengthens the contraction of the diaphragm muscles. Theophylline's half-life varies depending on several known factors; in adult nonsmokers with uncomplicated asthma, it typically ranges from 3 to 9 hours.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Theophylline dosing must be tailored to each person, guided by measurements of peak theophylline levels in the blood, so that the dose gives the greatest possible benefit with the least risk of side effects. Most sustained release products can be taken every 12 hours in adults, although some children whose livers break down theophylline unusually fast may need a dose every 8 hours. The recommended maintenance doses within the accepted therapeutic range are as follows. For those aged 16 years or older, 10 mg per kg per day, not exceeding 900 mg per day. For ages 12 to 15 years, 13 mg per kg per day. For ages 9 to 11 years, 16 mg per kg per day. For ages 1 to 8 years, 24 to 24 mg per kg per day. For ages 6 months to 1 year, 12 to 18 mg per kg per day. For ages 1 to 6 months, 10 mg per kg per day. Regarding use in children, theophylline is cleared from the body very slowly in newborns. In pediatric patients, doses must be chosen with great care and blood theophylline levels must be monitored closely.
Side Effects
Side effects are generally rare at normal doses. They may include gastrointestinal discomfort, headache, nausea, insomnia, and low blood pressure (hypotension). CNS stimulation and increased urination (diuresis) may also occur, particularly in children.
Cautions & Contraindications
Warnings & Precautions
Many medicines and physical conditions can change how quickly the body clears Asmaloc SR, so these interacting drugs and conditions need careful consideration. The dose may need to be adjusted before starting Asmaloc SR, before any increase in the Asmaloc SR dose, and during follow-up. Treatment should begin with a low dose of Asmaloc SR which, if well tolerated, is then increased slowly over time.
Contraindications
Theophylline should not be used by anyone who is allergic to theophylline itself or to any other ingredient in the product.
Pregnancy & Breastfeeding
Pregnancy: It isn't known whether theophylline can harm an unborn baby, so xanthine medicines like this one should be used during pregnancy only when clearly necessary.
Breastfeeding: Theophylline passes into breast milk and may make a nursing infant irritable or show other mild signs of toxicity. Serious harm to the baby is unlikely unless the mother's blood theophylline level is itself too high.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Theophylline, like all medicines, out of reach of children. Store it in a cool, dry place and protect it from light.
Drug Interactions
Common questions about Contine 400 mg
What is Contine 400 mg Tablet (Controlled Release)?
Contine 400 mg Tablet (Controlled Release) is a medicine that contains Theophylline. It is made by Aristopharma Limited. It belongs to the Bronchodilator group of medicines.
What is Contine used for?
Contine is used for: Asthma, Chronic Obstructive Pulmonary Disease, Bronchitis.
What are the side effects of Contine?
Side effects are generally rare at normal doses. They may include gastrointestinal discomfort, headache, nausea, insomnia, and low blood pressure (hypotension).
Can I take Contine during pregnancy or while breastfeeding?
Pregnancy: It isn't known whether theophylline can harm an unborn baby, so xanthine medicines like this one should be used during pregnancy only when clearly necessary. Breastfeeding: Theophylline passes into breast milk and may make a nursing infant irritable or show other mild signs of toxicity. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Contine?
Keep Theophylline, like all medicines, out of reach of children. Store it in a cool, dry place and protect it from light.
Can I take other medicines with Contine?
Some medicines can interact with Theophylline, for example: Methotrexate, Fluvoxamine Maleate, Obeticholic Acid, Econazole Nitrate + Triamcinolone Acetonide, Erythromycin, Levofloxacin. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Contine is already among the lowest-priced brands of Theophylline at this strength.
Do I need a prescription for Contine?
Contine is a prescription (Rx) medicine. Take it as your doctor advises.