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Indications & Uses
Pharmacology
Iron Polymaltose Complex is a polysaccharide-iron complex, a newer type of iron preparation used to treat iron deficiency anaemia. Iron is an essential part of the body. It is needed to form haemoglobin and for the oxidative process in living tissue.
The preparation holds non-ionic ferric iron and polymaltose together in a stable complex. This allows controlled absorption of the ferric iron when it touches the surface of the mucosal cells. Because it is non-ionic, it does not release free radicals, so it avoids the toxic effects that free radicals cause with traditional ionized iron salt preparations.
Iron Polymaltose Complex also does not interact with food components or other medicines. Unlike ferrous salts, its bioavailability does not fall. As a result, the iron is used faster in the synthesis of haemoglobin and myoglobin.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
How much Iron Polymaltose Complex you take, and for how long, depends on how deficient in iron you are, so take it as your physician directs. For adults the dose is 10 ml once or twice daily. Children aged 6 to 12 years take 10 ml daily, and children aged 2 to 6 years take 5 ml daily. For premature infants and infants the dose is 3.33 mg of elemental iron/kg body weight.
Side Effects
Most people tolerate Iron Polymaltose Complex well. Still, like other oral iron preparations, it can sometimes cause nausea, vomiting, constipation or diarrhoea.
Cautions & Contraindications
Warnings & Precautions
In an iron overdose, the first signs are pain in the upper abdomen (epigastric pain), diarrhoea and vomiting. Later there may be metabolic acidosis, convulsions and coma, which can appear after the person seems to have recovered. Speed matters for effective treatment, because the excess iron has to be removed from the alimentary tract before it is absorbed. An emetic should be given first, then gastric lavage with 1% sodium bicarbonate. After that, desferrioxamine is given by mouth to bind the iron that remains.
Contraindications
Iron Polymaltose Complex should not be used where there is a risk of iron overload, for example haemochromatosis, thalassemia or haemosiderosis. It should also not be used by anyone who is hypersensitive to iron or to any other ingredient of the syrup.
Pregnancy & Breastfeeding
Giving Iron Polymaltose Complex in the first trimester of pregnancy needs a careful look at the possible risk against the benefit the mother may gain. It should not be given unless it is clearly indicated. For the rest of the pregnancy, iron therapy may be indicated, but only on a physician's advice. Iron does pass into breast milk, though not in amounts that are clinically significant.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
In an overdose of Iron Polymaltose Complex, the first signs are usually pain in the upper stomach (epigastric pain), diarrhoea and vomiting. Metabolic acidosis, convulsions and coma can follow, and these may appear even after the person seems to have recovered. Anyone who has taken too much should get emergency medical attention. Treatment starts with an emetic, then gastric lavage, along with general supportive measures.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Iron Polymaltose Complex below 30°C, away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Compiron 50 mg/5 ml
What is Compiron 50 mg/5 ml Syrup?
Compiron 50 mg/5 ml Syrup is a medicine that contains Iron Polymaltose Complex. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Oral Iron preparations group of medicines.
What is Compiron used for?
Compiron is used for: Anemia, Cancer.
What are the side effects of Compiron?
Most people tolerate Iron Polymaltose Complex well. Still, like other oral iron preparations, it can sometimes cause nausea, vomiting, constipation or diarrhoea.
Can I take Compiron during pregnancy or while breastfeeding?
Giving Iron Polymaltose Complex in the first trimester of pregnancy needs a careful look at the possible risk against the benefit the mother may gain. It should not be given unless it is clearly indicated. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Compiron?
In an overdose of Iron Polymaltose Complex, the first signs are usually pain in the upper stomach (epigastric pain), diarrhoea and vomiting. Metabolic acidosis, convulsions and coma can follow, and these may appear even after the person seems to have recovered. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Compiron?
Store Iron Polymaltose Complex below 30°C, away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Compiron?
Some medicines can interact with Iron Polymaltose Complex, for example: Iron, Tetracycline Hydrochloride. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Compiron?
Compiron is a prescription (Rx) medicine. Take it as your doctor advises.