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Indications & Uses

Clonipres ER 0.2 Tablet is indicated for:

Pharmacology

Clonidine hydrochloride works by stimulating alpha adrenoceptors in the brain stem. With the immediate-release form, blood pressure begins to fall within 30 to 60 minutes of taking a dose, reaching its lowest point 2 to 4 hours later. It does not meaningfully affect renal blood flow or the glomerular filtration rate, and because normal postural reflexes remain intact, symptoms related to standing up (orthostatic symptoms) are mild and uncommon.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Adult: The dose of Clonidine Hydrochloride must be adjusted according to the patient's individual blood pressure response. Initial dose: 0.1 mg twice a day, taken in the morning and at bedtime. Elderly patients may benefit from a lower initial dose. Maintenance dose: further increments of 0.1 mg per day may be made at weekly intervals if necessary, until the desired result is achieved. The therapeutic dose most commonly employed has ranged from 0.2 mg to 0.6 mg per day, given in divided doses. In renal impairment, the dose of Clonidine Hydrochloride must be adjusted according to the degree of impairment, and the patient should be monitored carefully. For attention deficit hyperactivity disorder, Clonidine IR 5 mcg/kg/day or Clonidine ER 0.1 mg/day may be given for 8 weeks. For menopausal flushing, 0.1 mg to 0.4 mg daily may be given. For alcohol withdrawal, 0.3 to 0.6 mg may be given every 6 hours, or as directed by the physician. Use in children and adolescents: safety and effectiveness in pediatric patients have not been established in adequate and well controlled trials.

Side Effects

Most side effects of Clonipres ER are mild and tend to ease off as treatment continues. The most common ones, which seem to be dose-related, include dry mouth, drowsiness, dizziness, sedation, constipation, ear pain, irritability, diarrhea, abdominal pain, and nausea.

Cautions & Contraindications

Warnings & Precautions

Instruct patients not to stop taking this medicine on their own without consulting their physician. Stopping clonidine treatment abruptly can cause symptoms such as nervousness, agitation, headache, and tremor, along with a rapid rise in blood pressure and increased catecholamine levels in the blood. When stopping Clonipres ER Tablet, the dose should be reduced gradually over 2 to 4 days to avoid these withdrawal symptoms. If a patient is taking both a beta-blocker and clonidine and treatment is to be stopped, the beta-blocker should be withdrawn several days before Clonipres ER Tablet is gradually discontinued.

Contraindications

Clonidine should not be used by patients who are known to be hypersensitive to it.

Pregnancy & Breastfeeding

Pregnancy Category C. For this reason, Clonidine Hydrochloride is generally best avoided during pregnancy. It does pass into breast milk, so it should be used with caution in nursing mothers.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Overdose

An overdose of clonidine hydrochloride may cause hypotension, bradicardia, respiratory depression, hypothermia, sedation, abnormal reflexes, weakness and miosis.

⚠️ In an emergency call 999 or go to the nearest hospital emergency department.

Storage

Store Clonidine Hydrochloride below 30°C, and keep it away from light and moisture. Always keep it out of the reach of children.

Drug Interactions

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Common questions about Clonipres ER 0.2 Tablet 200 mcg

What is Clonipres ER 0.2 Tablet 200 mcg Er Tablet?

Clonipres ER 0.2 Tablet 200 mcg Er Tablet is a medicine that contains Clonidine Hydrochloride. It is made by Navana Pharmaceuticals Ltd. It belongs to the Centrally acting antihypertensive drugs (central sympatholytic) group of medicines.

What is Clonipres ER 0.2 Tablet used for?

Clonipres ER 0.2 Tablet is used for: Hypertension.

What are the side effects of Clonipres ER 0.2 Tablet?

Most side effects of Clonipres ER are mild and tend to ease off as treatment continues. The most common ones, which seem to be dose-related, include dry mouth, drowsiness, dizziness, sedation, constipation, ear pain, irritability, diarrhea, abdominal pain, and nausea.

Can I take Clonipres ER 0.2 Tablet during pregnancy or while breastfeeding?

Pregnancy Category C. For this reason, Clonidine Hydrochloride is generally best avoided during pregnancy. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

What happens if I take too much Clonipres ER 0.2 Tablet?

An overdose of clonidine hydrochloride may cause hypotension, bradicardia, respiratory depression, hypothermia, sedation, abnormal reflexes, weakness and miosis. In an emergency call 999 or go to the nearest hospital emergency department.

How should I store Clonipres ER 0.2 Tablet?

Store Clonidine Hydrochloride below 30°C, and keep it away from light and moisture. Always keep it out of the reach of children.

Can I take other medicines with Clonipres ER 0.2 Tablet?

Some medicines can interact with Clonidine Hydrochloride, for example: Tizanidine Hydrochloride, Glimepiride, Insulin Aspart [Protamine Crystallised], Biphasic Insulin Aspart, Nebivolol Hydrochloride, Insulin Glargine. Tell your doctor or pharmacist about every medicine you take.

Do I need a prescription for Clonipres ER 0.2 Tablet?

Clonipres ER 0.2 Tablet is a prescription (Rx) medicine. Take it as your doctor advises.

Last updated: 15 Aug 2026