Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Cefoperazone Sodium is used to treat infections caused by organisms that are susceptible to it. These include respiratory tract infections, peritonitis and other intra-abdominal infections, bacterial septicemia, and infections of the skin and skin structures. It is also used for pelvic inflammatory disease, endometritis and other infections of the female genital tract, urinary tract infections, enterococcal infections and similar conditions.
Pharmacology
Cefoperazone is a cephalosporin antibiotic that kills bacteria (it is bactericidal). It resists most beta-lactamases and works against many aerobic and anaerobic bacteria, both Gram positive and Gram negative. It kills bacteria by stopping them from building their cell walls.
Cefoperazone stays stable in the presence of the beta-lactamases that most Gram negative pathogens produce. Because of this, it is usually active against organisms that resist other beta-lactam antibiotics through beta-lactamase production.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Detailed dosing reference is not available yet. Please follow your prescription and consult your pharmacist.
Side Effects
Hypersensitivity reactions have been reported with Cefoperazone Sodium, as with all cephalosporins. These include skin reactions (1 patient in 45), drug fever (1 in 260) and a change in Coombs' test (1 in 60). They are more likely in patients with a history of allergies, particularly to penicillin.
Cautions & Contraindications
Warnings & Precautions
Cefoperazone Sodium leaves the body mostly through the bile. In people with liver disease, a blocked bile duct, or both, its half-life in the blood becomes 2 to 4 times longer. For these patients a total daily dose above 4 gm should not normally be needed. If a higher dose is used, the blood levels of Cefoperazone Sodium should be monitored.
Contraindications
Don't give Cefoperazone to anyone who is known to be allergic to the cephalosporin group of antibiotics.
Pregnancy & Breastfeeding
Cefoperazone Sodium is Pregnancy Category B. This drug should be used during pregnancy only if clearly needed. Only low concentrations of Cefoperazone are excreted in human milk. Cefoperazone passes poorly into the breast milk of nursing mothers, but caution should still be exercised when it is given to a nursing woman.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Children use: Safety and effectiveness of Cefoperazone Sodium in children have not been established.
Geriatric use: Reported clinical experience hasn't shown any difference in response between elderly and younger patients. Still, the dose for an elderly patient should be chosen with care, usually starting at the low end of the dosing range. This is because decreased liver, kidney or heart function is more common in older people, as are other diseases and other drug therapy taken at the same time.
Storage
Keep Cefoperazone Sodium in a dry place, below 25°C, and away from light until it is reconstituted. Once reconstituted, the solution can be kept for 24 hours at room temperature (below 25°C).
Common questions about Cefoject 1 gm
What is Cefoject 1 gm IM/IV Injection?
Cefoject 1 gm IM/IV Injection is a medicine that contains Cefoperazone Sodium. It is made by Eskayef Pharmaceuticals Ltd. It belongs to the Third generation cephalosporins group of medicines.
What is Cefoject used for?
Cefoperazone Sodium is used to treat infections caused by organisms that are susceptible to it. These include respiratory tract infections, peritonitis and other intra-abdominal infections, bacterial septicemia, and infections of the skin and skin structures.
What are the side effects of Cefoject?
Hypersensitivity reactions have been reported with Cefoperazone Sodium, as with all cephalosporins. These include skin reactions (1 patient in 45), drug fever (1 in 260) and a change in Coombs' test (1 in 60).
Can I take Cefoject during pregnancy or while breastfeeding?
Cefoperazone Sodium is Pregnancy Category B. This drug should be used during pregnancy only if clearly needed. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Cefoject?
Keep Cefoperazone Sodium in a dry place, below 25°C, and away from light until it is reconstituted. Once reconstituted, the solution can be kept for 24 hours at room temperature (below 25°C).
Do I need a prescription for Cefoject?
Cefoject is a prescription (Rx) medicine. Take it as your doctor advises.