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Indications & Uses
Pharmacology
Carisoprodol works as an indirect agonist at the GABA-A receptor, and it also affects chloride channel conductance in the CNS. GABA receptor agonists usually cause sedation, and they can also bring other effects such as reduced anxiety, control of seizures and muscle relaxation. Meprobamate, a metabolite of carisoprodol, has anxiolytic and sedative properties too.
Carisoprodol lowers the impulses that travel from the brain and spinal cord to the muscle. The muscle then relaxes, and so the spasm decreases. It has no direct action on the muscle itself.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
For adults aged 18 years and older, the recommended dose of Carisoprodol is 250 mg to 350 mg three times a day and at bedtime. It should be used for two or three weeks at most. Take care in patients with renal or hepatic impairment, and also in those with reduced CYP2C19 activity.
Side Effects
Carisoprodol most often causes drowsiness, dizziness and headache.
Cautions & Contraindications
Warnings & Precautions
Carisoprodol can make you drowsy, so it may affect your ability to do hazardous tasks such as driving or operating machinery. If you take it with other CNS depressants, including alcohol, the sedative effects add up. Drug dependence, withdrawal and abuse have been reported with carisoprodol. Seizures have also been reported.
Contraindications
Carisoprodol should not be given to anyone who has had acute intermittent porphyria in the past, or who has had a hypersensitivity reaction to a carbamate such as meprobamate.
Pregnancy & Breastfeeding
Carisoprodol is in pregnancy category C. If a mother takes it while breastfeeding, the baby may feed less well because of sedation, and her milk production may also fall. A nursing woman should be given Carisoprodol with caution.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Taking too much Carisoprodol usually causes CNS depression. Death, coma, respiratory depression, hypotension and seizures have all been reported after Carisoprodol overdose. Basic life support measures should be started straight away.
Don't induce vomiting, because of the risk of CNS and respiratory depression. Gastric lavage should be considered soon after the medicine is taken (within one hour). If needed, circulatory support is given with a volume infusion and vasopressor agents.
Seizures should be treated with intravenous benzodiazepines, and if they come back, phenobarbital may be used. In severe CNS depression the reflexes that protect the airway may be weakened, so tracheal intubation should be considered to protect the airway and support breathing.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Carisoprodol in a cool, dry place at room temperature, between 20°C and 25°C, and away from direct light. Keep it out of the reach of children.
Drug Interactions
Common questions about Cariso 350 mg
What is Cariso 350 mg Tablet?
Cariso 350 mg Tablet is a medicine that contains Carisoprodol. It is made by Opsonin Pharma Limited. It belongs to the Locally acting Skeletal Muscle Relaxants group of medicines.
What is Cariso used for?
Cariso is used for: Pain, Anxiety.
What are the side effects of Cariso?
Carisoprodol most often causes drowsiness, dizziness and headache.
Can I take Cariso during pregnancy or while breastfeeding?
Carisoprodol is in pregnancy category C. If a mother takes it while breastfeeding, the baby may feed less well because of sedation, and her milk production may also fall. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Cariso?
Taking too much Carisoprodol usually causes CNS depression. Death, coma, respiratory depression, hypotension and seizures have all been reported after Carisoprodol overdose. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Cariso?
Keep Carisoprodol in a cool, dry place at room temperature, between 20°C and 25°C, and away from direct light. Keep it out of the reach of children.
Can I take other medicines with Cariso?
Some medicines can interact with Carisoprodol, for example: Omeprazole, Rifampicin, Fluvoxamine Maleate. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Cariso is already among the lowest-priced brands of Carisoprodol at this strength.
Do I need a prescription for Cariso?
Cariso is a prescription (Rx) medicine. Take it as your doctor advises.