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Other brands with the same active ingredient
These brands contain the same active ingredient (Carbimazole). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Carbimazole is indicated for:
Pharmacology
Carbimazole belongs to the anti-thyroid class of medicines. It works by lowering the amount of thyroid hormone the body produces. It does this mainly by cutting down the formation of di-iodotyrosine and thyroxine, and to a lesser extent by reducing how much inorganic iodine the thyroid gland takes up and holds onto.
After being taken by mouth, carbimazole is absorbed quickly from the gut and spreads throughout the body. It is entirely converted in the body into methimazole, and it is this metabolite that actually produces the drug's therapeutic effect. Carbimazole crosses the placenta easily and also passes into breast milk in significant amounts, which is worth bearing in mind for pregnant or breastfeeding patients.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Initial dose: 20-60 mg daily, given in 2-3 divided doses until the patient becomes euthyroid; the total daily amount should be split across doses rather than taken all at once. Maintenance regimen: once thyroid function normalizes, the dose is gradually lowered, usually settling at 5-15 mg/day, which can then be taken as a single daily dose. Neonates and children below 12 years: the usual initial dose is 250 mcg/kg/day, given in divided doses. Duration of treatment is typically 18 to 24 months.
Side Effects
Side effects may include rash, itching, skin pigmentation changes, tingling sensations, hives, headache, joint pain, and gastro-intestinal disturbances such as nausea, vomiting, and gastric discomfort, as well as unusual hair loss. There have also been reports of drug fever, a lupus-like syndrome, vasculitis and nephritis, liver disorders (most commonly jaundice), and taste disturbances following Carbiroid therapy.
Cautions & Contraindications
Warnings & Precautions
Carbiroid should be given with the utmost caution, or not at all, if there is any degree of tracheal obstruction, since high dosages may cause the thyroid gland to enlarge, and obstructive symptoms may become pronounced.
Contraindications
Known hypersensitivity to carbimazole or other thiourea antithyroid drugs.
Pregnancy & Breastfeeding
Carbimazole can be used during pregnancy in patients with thyrotoxicosis, but it should be given at the lowest dose that keeps the condition controlled, since taking too much can harm the developing baby. The drug also crosses the placenta and passes into breast milk, so it may lead to an underactive thyroid or goitre in the foetus or newborn.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Taking too much carbimazole, or taking it by accident, can lead to hypothyroidism and goitre. If blood dyscrasias develop, stop the medicine immediately. After that, treatment is symptomatic and supportive.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Carbimazole below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Carbimazole 5 mg
What is Carbimazole 5 mg Tablet?
Carbimazole 5 mg Tablet is a medicine that contains Carbimazole. It is made by Popular Pharmaceuticals PLC. It belongs to the Anti-thyroid drugs group of medicines.
What is Carbimazole used for?
Carbimazole is used for: Hyperthyroidism.
What are the side effects of Carbimazole?
Side effects may include rash, itching, skin pigmentation changes, tingling sensations, hives, headache, joint pain, and gastro-intestinal disturbances such as nausea, vomiting, and gastric discomfort, as well as unusual hair loss. There have also been reports of drug fever, a lupus-like syndrome, vasculitis and nephritis, liver disorders (most commonly jaundice), and taste disturbances following Carbiroid therapy.
Can I take Carbimazole during pregnancy or while breastfeeding?
Carbimazole can be used during pregnancy in patients with thyrotoxicosis, but it should be given at the lowest dose that keeps the condition controlled, since taking too much can harm the developing baby. The drug also crosses the placenta and passes into breast milk, so it may lead to an underactive thyroid or goitre in the foetus or newborn. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Carbimazole?
Taking too much carbimazole, or taking it by accident, can lead to hypothyroidism and goitre. If blood dyscrasias develop, stop the medicine immediately. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Carbimazole?
Store Carbimazole below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Carbimazole?
Some medicines can interact with Carbimazole, for example: Iodine, Digoxin. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Carbimazole?
Carbimazole is a prescription (Rx) medicine. Take it as your doctor advises.