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Other brands with the same active ingredient
These brands contain the same active ingredient (Tetracycline Hydrochloride). Same strength and form. Confirm the switch with your doctor or pharmacist.
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Other strengths and forms by Millat Pharmaceuticals Ltd.
Indications & Uses
Capcin is indicated for:
Pharmacology
Tetracycline is a broad-spectrum antibiotic that stops the growth of many bacteria as well as rickettsiae, chlamydia, mycoplasma, and brucella. It works by blocking protein synthesis in these organisms. Taken as a single oral dose, it reaches its peak level in the blood within 2 to 4 hours, and its half-life ranges from 6 to 9 hours. Because it undergoes enterohepatic circulation, Tetracycline can remain detectable in the blood for some time even after treatment has stopped.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Usual adult dosage is 250 mg or 500 mg every 6 hours by mouth, preferably taken 1 hour before or 2 hours after a meal. Higher doses of up to 3 or 4 gm daily have occasionally been given in resistant infections. Specific dosage recommendations are as follows. Brucellosis: 500 mg every 6 hours for 3 weeks. Chlamydial infections: 500 mg every 6 hours for at least 2 weeks. Non-specific urethritis: 500 mg every 6 hours for 7 days. Severe acne: 1 gm per day for 2 to 3 weeks, followed by 1 capsule daily for 3 to 4 months. Gonorrhoea: an initial oral dose of 1.5 gm, followed by 500 mg every 6 hours for 4 days; the total dose should be 9 gm. Syphilis: 500 mg every 6 hours for 15 days, but therapy should be continued for 30 days if the disease has been present for longer than 1 year. Endocervical infections: 500 mg every 6 hours for 7 days. Children over 12 years of age: 25 to 50 mg/kg divided into 2 or 4 equal doses. The maximum dose should not exceed the recommended adult dose. Children below 12 years of age: not recommended. Administration: Tetracycline should be taken orally, an hour before or two hours after a meal, and therapy should be continued for up to three days after the characteristic symptoms of the infection have subsided. It should be used with caution in the treatment of elderly patients, in whom accumulation is a possibility.
Side Effects
Tetracycline can upset the digestive system, causing problems such as glossitis (inflamed tongue), stomatitis (sores in the mouth), vaginitis, or staphylococcal enterocolitis (a bowel infection). Sensitivity to sunlight and skin reactions are rare. Bulging of the soft spot on the head (fontanelle) in infants and benign intracranial hypertension (raised pressure inside the skull) in adults have been reported. If intracranial pressure rises, treatment should be stopped. Hypersensitivity (allergic) reactions may occur, including purpura (purple spots on the skin), pericarditis (inflammation of the lining around the heart), angioneurotic oedema (swelling under the skin), anaphylaxis, anaphylactoid purpura, and a flare-up of systemic lupus erythematosus. Haemolytic anaemia, thrombocytopenia (low platelets), neutropenia (low white blood cells), and eosinophilia have also been reported.
Cautions & Contraindications
Warnings & Precautions
Absorption of tetracycline is reduced when it is taken together with milk, or with calcium, magnesium, iron and especially aluminium salts, which are commonly found in antacids. Tetracycline lowers plasma prothrombin activity, so patients taking anticoagulants at the same time may need a reduced anticoagulant dose. In patients with impaired kidney function, lower doses are indicated to prevent excessive build-up of the drug in the body, and if treatment is prolonged, serum level monitoring is advisable. Oral tetracycline taken alongside oral contraceptives or penicillins may make these less effective, and breakthrough bleeding may occur more often. It should be used only with great caution together with other drugs that can damage the liver.
Contraindications
Tetracycline should not be used by anyone with a known allergy to tetracycline, by people with significant kidney failure, by children under 12 years of age, or by women who are pregnant or breastfeeding.
Pregnancy & Breastfeeding
During pregnancy, tetracycline crosses the placenta, is found in foetal tissues and has an embryotoxic effect. For this reason, it should not be used in pregnancy unless considered essential, in which case the maximum daily dose should be 1 gm. Tetracycline has also been found in human milk, and its use during breastfeeding may cause permanent tooth discoloration in the developing infant; enamel hypoplasia has also been reported.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Tetracycline Hydrochloride in a cool, dry place and away from light. Make sure children can't reach it.
Drug Interactions
Common questions about Capcin 500 mg
What is Capcin 500 mg Capsule?
Capcin 500 mg Capsule is a medicine that contains Tetracycline Hydrochloride. It is made by Millat Pharmaceuticals Ltd. It belongs to the Tetracycline group of drugs group of medicines.
What is Capcin used for?
Capcin is used for: Fever, Peptic Ulcer, Helicobacter Pylori Infection, Amoebiasis, Acne Vulgaris, Conjunctivitis.
What are the side effects of Capcin?
Tetracycline can upset the digestive system, causing problems such as glossitis (inflamed tongue), stomatitis (sores in the mouth), vaginitis, or staphylococcal enterocolitis (a bowel infection). Sensitivity to sunlight and skin reactions are rare.
Can I take Capcin during pregnancy or while breastfeeding?
During pregnancy, tetracycline crosses the placenta, is found in foetal tissues and has an embryotoxic effect. For this reason, it should not be used in pregnancy unless considered essential, in which case the maximum daily dose should be 1 gm. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Capcin?
Keep Tetracycline Hydrochloride in a cool, dry place and away from light. Make sure children can't reach it.
Can I take other medicines with Capcin?
Some medicines can interact with Tetracycline Hydrochloride, for example: Magaldrate + Simethicone, Ferrous Ascorbate + Folic Acid + Zinc Sulfate, Methotrexate, Magnesium, Calcium Carbonate, Conventional Calcium + Vitamin D3. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Capcin?
Capcin is a prescription (Rx) medicine. Take it as your doctor advises.