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Same active ingredient — pay up to 63% less
These brands contain the same active ingredient (Bicalutamide). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Calupros is indicated for:
Pharmacology
Bicalutamide belongs to a class of medicines called non-steroidal androgen receptor inhibitors. It works by attaching to androgen receptors within the target tissue, thereby blocking the action of androgens (male hormones) at those sites. Prostate cancer is generally androgen-sensitive, meaning it tends to respond to treatments that either counteract the effect of androgens or reduce the amount of androgen available in the body.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
When bicalutamide is given together with an LHRH analogue, the usual adult dose is one 50 mg tablet taken once a day, in the morning or evening, with or without food.
Pediatric use: The safety and effectiveness of bicalutamide in pediatric patients have not been established.
Hepatic impairment: Bicalutamide is broken down extensively by the liver, so it should be used with caution in patients with moderate-to-severe hepatic impairment.
Side Effects
Side effects reported in more than 10% of patients taking Casodex together with an LHRH-A were: hot flashes, pain (including general, back, pelvic, and abdominal pain), weakness (asthenia), constipation, infection, nausea, swelling of the hands and feet (peripheral edema), shortness of breath (dyspnea), diarrhea, blood in the urine (hematuria), needing to urinate at night (nocturia), and anemia.
Cautions & Contraindications
Warnings & Precautions
Bleeding can occur when Casodex is taken together with a coumarin anticoagulant. Your doctor will check your Prothrombin Time (PT) and International Normalized Ratio (INR) closely and change the anticoagulant dose if needed. Gynecomastia (breast enlargement) and breast pain have been reported during treatment with Casodex 150 mg when it is used on its own. Casodex can reduce glucose tolerance in men, so consideration should be given to monitoring blood glucose in patients who take Casodex together with LHRH agonists. Your doctor is likely to recommend regular Prostate Specific Antigen (PSA) monitoring. If your PSA rises, your doctor should check whether the disease is getting worse.
Contraindications
Bicalutamide must not be taken by anyone who has previously had a hypersensitivity reaction to the drug or to any of the tablet's ingredients. Bicalutamide is not indicated for women and should not be used in this group.
Pregnancy & Breastfeeding
Bicalutamide should never be used during pregnancy, as it may harm the developing baby. It is not intended for use in women at all, and no human studies exist on its use during pregnancy.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Pediatric Use
The safety and effectiveness of Bical in pediatric patients have not been established.
Hepatic Impairment
For hepatic-impaired patients on long-term therapy, periodic liver function tests should be considered.
Renal Impairment
Renal impairment (as measured by creatinine clearance) had no significant effect on the elimination of total Bical or the active R-enantiomer.
Overdose
Long-term clinical trials have tested Bical at doses of up to 200 mg daily, and people tolerated these doses well. No single dose of Bical has been established as causing overdose symptoms that would be life threatening. There is no specific antidote, so an overdose should be treated by managing the symptoms.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Bicalutamide in a dry place where the temperature stays at or below 30°C. Protect it from light and moisture.
Common questions about Calupros 50 mg
What is Calupros 50 mg Tablet?
Calupros 50 mg Tablet is a medicine that contains Bicalutamide. It is made by Everest Pharmaceuticals Ltd. It belongs to the Hormonal Chemotherapy group of medicines.
What is Calupros used for?
Calupros is used for: Cancer.
What are the side effects of Calupros?
Side effects reported in more than 10% of patients taking Casodex together with an LHRH-A were: hot flashes, pain (including general, back, pelvic, and abdominal pain), weakness (asthenia), constipation, infection, nausea, swelling of the hands and feet (peripheral edema), shortness of breath (dyspnea), diarrhea, blood in the urine (hematuria), needing to urinate at night (nocturia), and anemia.
Can I take Calupros during pregnancy or while breastfeeding?
Bicalutamide should never be used during pregnancy, as it may harm the developing baby. It is not intended for use in women at all, and no human studies exist on its use during pregnancy. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Calupros?
Long-term clinical trials have tested Bical at doses of up to 200 mg daily, and people tolerated these doses well. No single dose of Bical has been established as causing overdose symptoms that would be life threatening. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Calupros?
Keep Bicalutamide in a dry place where the temperature stays at or below 30°C. Protect it from light and moisture.
Is there a cheaper medicine with the same ingredient?
Bicalon by Drug International Unani Ltd. has the same ingredient and strength for ৳30.00 per unit, compared with ৳80.00 for Calupros. Ask your doctor or pharmacist before switching.
Do I need a prescription for Calupros?
Calupros is a prescription (Rx) medicine. Take it as your doctor advises.