Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Save on this medicine
Same active ingredient — pay up to 18% less
These brands contain the same active ingredient (Calcitriol). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Caltrol
Other strengths and forms by Pacific Pharmaceuticals Ltd.
Indications & Uses
Caltrol is indicated for:
Pharmacology
Calcitriol is one of the most important active forms of vitamin D3. It is normally produced in the kidneys from its precursor, 25-hydroxycholecalciferol. Calcitriol helps the intestines absorb calcium and helps regulate how bone tissue is mineralized. Its key role is maintaining calcium balance in the body, which includes stimulating osteoblast activity (the bone-building cells) in the skeleton.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The optimal daily dose of Calcitriol capsule must be carefully determined for each patient on the basis of serum calcium level.
In Post-menopausal Osteoporosis: The recommended dose of Calcitriol capsule is 0.25 mcg twice daily.
In Renal Osteodystrophy (dialysis patients): The initial daily dose is 0.25 mcg of Calcitriol capsule. In patients with normal or only slightly reduced calcium levels, doses of 0.25 mcg every other day are sufficient.
In Hypoparathyroidism and Rickets: The recommended initial dosage of Calcitriol capsule is 0.25 mcg per day, given in the morning. If a satisfactory response is not observed within 2 to 4 weeks on the usual dose, the dose may be increased at intervals of 2 to 4 weeks. The recommended intravenous initial dose of Calcitriol injection, depending on the severity of the hypocalcemia and/or secondary hyperparathyroidism, is 1 mcg (0.02 mcg/kg) to 2 mcg, administered three times weekly, at intervals of approximately every other day. Doses as small as 0.5 mcg and as large as 4 mcg three times weekly have been used as an initial dose. If a satisfactory response is not observed, the dose may be increased by 0.5 to 1 mcg at intervals of two to four weeks.
Side Effects
Early side effects of Improcal injection may include weakness, headache, drowsiness, nausea, vomiting, dry mouth, constipation, muscle pain, bone pain and a metallic taste in the mouth. Later side effects can include excessive urination, excessive thirst, loss of appetite, weight loss, needing to urinate at night, calcific conjunctivitis, pancreatitis, sensitivity to light, runny nose, itching, elevated body temperature, reduced sex drive, raised blood urea nitrogen (BUN), protein in the urine, high cholesterol, elevated liver enzymes (SGOT and SGPT), abnormal calcium deposits in tissue, high blood pressure, irregular heartbeat and, rarely, overt psychosis. Mild pain at the injection site may occasionally occur.
Cautions & Contraindications
Warnings & Precautions
Excessive doses of Improcal injection can cause hypercalcemia and, in some cases, hypercalciuria. It should be used cautiously in patients taking digitalis, since hypercalcemia in these patients may trigger cardiac arrhythmias. Stopping Improcal injection therapy may cause a rebound effect, so the dose should be tapered down gradually to a maintenance level rather than stopped abruptly. If hypercalcemia occurs, the drug should be stopped right away. As Improcal injection is the most potent form of vitamin D available, vitamin D and its related compounds should not be taken during treatment. Patients on dialysis should use a non-aluminum phosphate-binding agent to keep serum phosphorus levels under control. Long-term hypercalcemia can lead to widespread calcification of blood vessels, calcium deposits in the kidneys, and calcification of other soft tissues.
Contraindications
Calcitriol should not be used by anyone who has a known allergy or hypersensitivity to any of its ingredients. It should also be avoided in all diseases linked with hypercalcaemia, meaning a raised level of calcium in the blood.
Pregnancy & Breastfeeding
Calcitriol, a vitamin used in bone formation, has not been shown to cause birth defects in humans. Even so, it should be used in pregnancy only if the expected benefit to the mother justifies the possible risk to the unborn baby. Breastfeeding mothers may continue taking Calcitriol, but calcium levels in both the mother's and the baby's blood should be monitored while doing so.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Secondary hyperparathyroidism in people with moderate to severe chronic renal failure (pre-dialysis)
For adults and children aged 3 years or older, the recommended starting dose of Calcitriol is 0.25 mcg/day. If needed, the doctor may raise this to 0.5 mcg/day. For children under 3 years of age, the recommended starting dose is 10 to 15 ng/kg/day.
In the elderly, no dose adjustment is required.
Overdose
If a patient gets more Calcitriol injection than they need, it can cause hypercalcemia, hypercalciuria and hyperphosphatemia. Hypercalcemia (greater than 1 mg/dL) is generally treated by stopping Calcitriol injection therapy straight away, putting the patient on a low calcium diet and withdrawing any calcium supplements.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Calcitriol in a dry place, away from light and heat. Keep it out of the reach of children.
Drug Interactions
Common questions about Caltrol 0.25 mcg
What is Caltrol 0.25 mcg Capsule?
Caltrol 0.25 mcg Capsule is a medicine that contains Calcitriol. It is made by Pacific Pharmaceuticals Ltd. It belongs to the Vitamin in bone formation group of medicines.
What is Caltrol used for?
Caltrol is used for: Osteoporosis.
What are the side effects of Caltrol?
Early side effects of Improcal injection may include weakness, headache, drowsiness, nausea, vomiting, dry mouth, constipation, muscle pain, bone pain and a metallic taste in the mouth. Later side effects can include excessive urination, excessive thirst, loss of appetite, weight loss, needing to urinate at night, calcific conjunctivitis, pancreatitis, sensitivity to light, runny nose, itching, elevated body temperature, reduced sex drive, raised blood urea nitrogen (BUN), protein in the urine, high cholesterol, elevated liver enzymes (SGOT and SGPT), abnormal calcium deposits in tissue, high blood pressure, irregular heartbeat and, rarely, overt psychosis.
Can I take Caltrol during pregnancy or while breastfeeding?
Calcitriol, a vitamin used in bone formation, has not been shown to cause birth defects in humans. Even so, it should be used in pregnancy only if the expected benefit to the mother justifies the possible risk to the unborn baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Caltrol?
If a patient gets more Calcitriol injection than they need, it can cause hypercalcemia, hypercalciuria and hyperphosphatemia. Hypercalcemia (greater than 1 mg/dL) is generally treated by stopping Calcitriol injection therapy straight away, putting the patient on a low calcium diet and withdrawing any calcium supplements. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Caltrol?
Keep Calcitriol in a dry place, away from light and heat. Keep it out of the reach of children.
Can I take other medicines with Caltrol?
Some medicines can interact with Calcitriol, for example: Conventional Calcium + Vitamin D3, Ibandronic Acid + Algae Calcium + Vitamin D3, Magnesium, Calcium Lactate Gluconate + Calcium Carbonate + Vitamin D3, Calcium Gluconate, Eggshell Calcium + Vitamin D3. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Improcal by Opsonin Pharma Limited has the same ingredient and strength for ৳9.00 per unit, compared with ৳11.00 for Caltrol. Ask your doctor or pharmacist before switching.
Do I need a prescription for Caltrol?
Caltrol is a prescription (Rx) medicine. Take it as your doctor advises.