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Other brands with the same active ingredient

These brands contain the same active ingredient (Calcium Orotate). Same strength and form. Confirm the switch with your doctor or pharmacist.

Available as: 400 mg

Indications & Uses

Caltrate 400 is indicated for:

Pharmacology

This medicine contains calcium orotate, a calcium supplement that carries orotic acid as its chelating partner. Orotic acid is an amino acid-type compound that helps move calcium across cell membranes, so the calcium can get into cells more easily, especially bone cells. Calcium orotate also supports healthy cartilage. Orotic acid plays a part in making DNA (deoxyribonucleic acid) and RNA (ribonucleic acid). Among the calcium supplements on the market, calcium orotate is rated well because it can get through complex cell membranes and be broken down by the body in cartilage.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Calcium Orotate 400 mg: As an addition to the daily diet, 2 to 3 tablets are usually recommended with a meal, or as directed by a physician. Calcium Orotate 740 mg: As an addition to the daily diet, 1 to 2 tablets are usually recommended with a meal, or as directed by a physician.

Side Effects

Bloating and abdominal swelling are common side effects of Rotate. Loss of appetite, an upset stomach, constipation, nausea, vomiting, unexplained weight loss, increased thirst or urination, weakness, unusual tiredness, and kidney stone formation may occur infrequently.

Cautions & Contraindications

Warnings & Precautions

Before taking Rotate, caution is needed if the patient is allergic to it. Rotate may contain inactive ingredients that can cause allergic reactions or other problems. Caution is also needed before using Rotate in patients with kidney disease, kidney stones, little or no stomach acid (achlorhydria), heart disease, disease of the pancreas, sarcoidosis, or difficulty absorbing nutrients from food (malabsorption syndrome).

Contraindications

Calcium Orotate should not be used by anyone with constipation, kidney stones, kidney disease, an overactive parathyroid gland, excess calcium in the urine, excess calcium in the blood, or severe dehydration.

Pregnancy & Breastfeeding

Pregnant and breastfeeding women have a higher calcium requirement. High blood pressure during pregnancy is a common but serious risk to both mother and baby, and taking a supplement such as Calcium Orotate may help lower this risk.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Storage

Store Calcium Orotate in a cool, dry place and keep it away from light. Always keep it out of the reach of children.

Drug Interactions

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Moderate Ciprofloxacin
Moderate Ibuprofen
Moderate Aspirin
Moderate Doxycycline
Moderate Levofloxacin
Moderate Minocycline
Moderate Phenytoin
Moderate Magnesium

Common questions about Caltrate 400 400 mg

What is Caltrate 400 400 mg Tablet?

Caltrate 400 400 mg Tablet is a medicine that contains Calcium Orotate. It is made by General Pharmaceuticals Ltd. It belongs to the Minerals in bone formation group of medicines.

What is Caltrate 400 used for?

Caltrate 400 is used for: Osteoporosis, Psoriasis, Calcium Deficiency, Cancer.

What are the side effects of Caltrate 400?

Bloating and abdominal swelling are common side effects of Rotate. Loss of appetite, an upset stomach, constipation, nausea, vomiting, unexplained weight loss, increased thirst or urination, weakness, unusual tiredness, and kidney stone formation may occur infrequently.

Can I take Caltrate 400 during pregnancy or while breastfeeding?

Pregnant and breastfeeding women have a higher calcium requirement. High blood pressure during pregnancy is a common but serious risk to both mother and baby, and taking a supplement such as Calcium Orotate may help lower this risk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

How should I store Caltrate 400?

Store Calcium Orotate in a cool, dry place and keep it away from light. Always keep it out of the reach of children.

Can I take other medicines with Caltrate 400?

Some medicines can interact with Calcium Orotate, for example: Ciprofloxacin, Ibuprofen, Aspirin, Doxycycline, Levofloxacin, Minocycline. Tell your doctor or pharmacist about every medicine you take.

Do I need a prescription for Caltrate 400?

Caltrate 400 is a prescription (Rx) medicine. Take it as your doctor advises.

Last updated: 15 Aug 2026