Indications & Uses
Calcin-O Kit is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The recommended dose of Ibandronic Acid is one 150 mg tablet once a month, on the same date each month. To get the full clinical benefit, two Calcium Orotate tablets a day are usually recommended, taken in divided doses. Take the Ibandronic Acid tablet from this Kit at least 60 minutes before the first food or drink of the day (plain water is fine) and before any oral medicine or supplement, including calcium, antacids or vitamins. This gives better absorption and clinical benefit. Swallow the tablet whole with a full glass of plain water (250 ml) while standing or sitting upright. That helps it reach the stomach and lowers the chance of irritation of the oesophagus. The patient should not lie down for 60 minutes after taking the tablet. The 150 mg tablet should always be taken on the same date each month, which is the patient's Ibandronic Acid day.
If the monthly dose is missed and the next scheduled Ibandronic Acid day is more than 7 days away, the patient should take one Ibandronic Acid 150 mg tablet in the morning after the day they remember. After that, they go back to one tablet every month, in the morning of their chosen day, following the original schedule. If the next scheduled Ibandronic Acid day is only 1 to 7 days away, the patient must wait and take the tablet on the scheduled day of the following month. Then they return to one 150 mg tablet every month, in the morning of their chosen day, according to the original schedule. The patient must not take two Ibandronic Acid 150 mg tablets within the same week.
Start the Calcium Orotate tablets on the day after the Ibandronic Acid day (from day-2 and onwards).
Side Effects
Ibandronic Acid commonly causes hypertension, dyspepsia, nausea, diarrhea and abdominal pain. Joint and muscle problems are also seen, including arthralgia, back pain, localized osteoarthritis, myalgia and muscle cramp. Other common effects are influenza, nasopharyngitis, bonchitis, urinary tract infection, upper respiratory tract infection, headache, dizziness, skin rash and insomnia, among others. With Calcium Orotate, bloating and swelling in the abdomen are the common side effects. Loss of appetite, upset stomach, constipation, nausea, vomiting, unusual weight loss, mood changes, bone or muscle pain, headache, increased thirst or urination, weakness and unusual tiredness may also occur. The formation of kidney stones may occur infrequently.
Cautions & Contraindications
Warnings & Precautions
Ibandronic Acid in this kit may irritate the lining of the upper gastrointestinal tract. Getting enough calcium is important for all patients, and hypocalcaemia needs to be corrected. Severe and sometimes incapacitating bone, joint and/or muscle pain has been reported in patients taking Ibandronic Acid. It is not recommended for patients with severe renal impairment (creatinine clearance of <30 ml/min). For Calcium Orotate, take care before starting it if the patient is allergic to Calcium Orotate. Any calcium supplement taken without food may raise the risk of kidney stones, so it is advisable to take Calcium Orotate with food.
Contraindications
Ibandronic Acid should not be used by people with abnormalities of the esophagus, low blood calcium (hypocalcemia), or a known hypersensitivity to Ibandronic Acid or any of its components. Calcium Orotate should not be used by people with incomplete bowel movements, kidney stone, kidney disease or lung disease.
Pregnancy & Breastfeeding
There are no adequate and well-controlled studies of this kit (Ibandronic Acid & Calcium Orotate) in pregnant women. So it should be used during pregnancy only if the likely benefit justifies the possible risk to the mother and the fetus. It isn't known whether the kit passes into human milk, and for that reason caution is needed when it is given to a nursing woman.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Children: the safety and effectiveness of Ibandronic Acid & Calcium Orotate have not been established in pediatric patients.
Kidney and liver problems: people with mild or moderate renal impairment, where creatinine clearance is equal to or greater than 30 ml/min, need no dose adjustment. No dose adjustment is required for patients with hepatic impairment either.
Storage
Keep Ibandronic Acid & Calcium Orotate in a cool, dry place and away from light. Like all medicines, it should be kept where children can't reach it.
Drug Interactions
Common questions about Calcin-O Kit 150 mg
What is Calcin-O Kit 150 mg Tablet?
Calcin-O Kit 150 mg Tablet is a medicine that contains Ibandronic Acid & Calcium Orotate. It is made by Renata PLC. It belongs to the Minerals in bone formation group of medicines.
What is Calcin-O Kit used for?
Calcin-O Kit is used for: Osteoporosis.
What are the side effects of Calcin-O Kit?
Ibandronic Acid commonly causes hypertension, dyspepsia, nausea, diarrhea and abdominal pain. Joint and muscle problems are also seen, including arthralgia, back pain, localized osteoarthritis, myalgia and muscle cramp.
Can I take Calcin-O Kit during pregnancy or while breastfeeding?
There are no adequate and well-controlled studies of this kit (Ibandronic Acid & Calcium Orotate) in pregnant women. So it should be used during pregnancy only if the likely benefit justifies the possible risk to the mother and the fetus. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Calcin-O Kit?
Keep Ibandronic Acid & Calcium Orotate in a cool, dry place and away from light. Like all medicines, it should be kept where children can't reach it.
Can I take other medicines with Calcin-O Kit?
Some medicines can interact with Ibandronic Acid & Calcium Orotate, for example: Ciprofloxacin, Aspirin, Doxycycline, Levofloxacin, Calcium Orotate, Iron. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Calcin-O Kit?
Calcin-O Kit is a prescription (Rx) medicine. Take it as your doctor advises.