Pricing
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Brofex TS is indicated for:
Pharmacology
Dextromethorphan Hydrobromide is a cough suppressant. It acts centrally, on the cough center in the medulla. Its structure is related to morphine, but it has no pain-relieving action and in general causes little sedation. Addiction has not been seen even after rather large doses were given for a prolonged period. The medicine is absorbed rapidly from the GI tract and begins to work 15 to 30 minutes after it is taken by mouth.
Polistirex forms a matrix around the Dextromethorphan particles. This slows how fast the Dextromethorphan dissolves in the gastrointestinal tract, so it enters the bloodstream gradually and over a longer time. With the extended release suspension, the action lasts 12 hours.
The liver metabolizes Dextromethorphan Hydrobromide extensively. It is excreted in the urine as unchanged Dextromethorphan and as de-methylated metabolites, including Dextrophan, which has some cough suppressant activity. Urinary excretion of the parent drug and metabolites accounts for up to 50% of the ingested dose over 24 hours. About 8% of the dose is excreted unchanged in the urine over the first 6 hours.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and children 12 years of age and over take 10 ml every 12 hours, and should not go above 20 ml in 24 hours.
Children aged 06 to 12 years take 5 ml every 12 hours, with a limit of 10 ml in 24 hours.
Children aged 04 to 06 years take 2.5 ml every 12 hours, with a limit of 5 ml in 24 hours.
Dextromethorphan Polistirex is not recommended for children under 04 years of age.
Side Effects
Side effects from Dextromethorphan Polistirex are rare, though nausea and dizziness do sometimes happen. The medicine gives no pain relief and doesn't cause addiction, and it causes little or no CNS depression. After an overdose, a person may become excited or confused, and breathing may slow down (respiratory depression).
Cautions & Contraindications
Warnings & Precautions
Dextromethorphan Polistirex is broken down heavily in the liver, so doctors should prescribe it with caution to patients who have liver disease.
Contraindications
Dextromethorphan Polistirex must not be taken together with monoamine oxidase inhibitors.
Pregnancy & Breastfeeding
There isn't much information on how Dextromethorphan Polistirex behaves in pregnancy, so it should be avoided during the first three months. Nothing is known about whether dextromethorphan passes into breast milk either, and for that reason nursing mothers should be advised not to take it.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Dextromethorphan Polistirex in a dry place, below 30°C, and away from light. Always keep it out of reach of children.
Drug Interactions
Common questions about Brofex TS 30 mg/5 ml
What is Brofex TS 30 mg/5 ml Extend Release Suspension?
Brofex TS 30 mg/5 ml Extend Release Suspension is a medicine that contains Dextromethorphan Polistirex. It is made by Square Pharmaceuticals PLC, Pabna. It belongs to the Cough suppressant group of medicines.
What is Brofex TS used for?
Brofex TS is used for: Cough.
What are the side effects of Brofex TS?
Side effects from Dextromethorphan Polistirex are rare, though nausea and dizziness do sometimes happen. The medicine gives no pain relief and doesn't cause addiction, and it causes little or no CNS depression.
Can I take Brofex TS during pregnancy or while breastfeeding?
There isn't much information on how Dextromethorphan Polistirex behaves in pregnancy, so it should be avoided during the first three months. Nothing is known about whether dextromethorphan passes into breast milk either, and for that reason nursing mothers should be advised not to take it. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Brofex TS?
Keep Dextromethorphan Polistirex in a dry place, below 30°C, and away from light. Always keep it out of reach of children.
Can I take other medicines with Brofex TS?
Some medicines can interact with Dextromethorphan Polistirex, for example: Dextromethorphan Hydrobromide. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Brofex TS?
Brofex TS is a prescription (Rx) medicine. Take it as your doctor advises.