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Indications & Uses
Bricoma is indicated for:
Pharmacology
Brimonidine is an α-2 adrenoreceptor agonist with greater selectivity for the α-2 receptor than the α-1 receptor. Applied topically, Brimonidine Tartrate eye drops lower intraocular pressure (IOP) in humans. When used as directed, Brimonidine Tartrate reduces elevated IOP while having minimal effect on cardiovascular parameters. The eye drops act quickly, with the peak IOP-lowering effect seen around two hours after dosing, and this effect lasts 12 hours or longer. Fluorophotometric studies in both animals and humans point to a dual mechanism of action: Brimonidine Tartrate eye drops lower IOP by reducing the production of aqueous humor and by improving uveoscleral outflow.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
For the 0.2% eye drops, the usual adult dose is one drop in the affected eye or eyes, three times a day, about 8 hours apart. This solution can be used alongside other eye drops to lower intraocular pressure. If you're using more than one eye drop product, leave at least 5 minutes between them.
The 0.15% eye drops are dosed the same way: one drop in the affected eye or eyes three times a day, roughly 8 hours apart.
For the 0.025% eye drops, put 1 drop in the affected eye or eyes every 6 to 8 hours. Don't use them more than 4 times a day. As with the other strengths, if you're using more than one eye drop product, keep at least 5 minutes between each one.
Side Effects
Adverse events occurred in about 10 to 30 percent of subjects, and in descending order of frequency included dryness of the mouth, redness of the eye, burning and stinging, headache, blurred vision, a sensation of something in the eye, fatigue or drowsiness, conjunctival follicles, ocular allergic reactions, and itching of the eye. Events occurring in about 3 to 9 percent of subjects, again in descending order, included corneal staining or erosion, sensitivity to light, redness of the eyelid, eye ache or pain, dryness of the eye, tearing, upper respiratory symptoms, eyelid swelling, conjunctival swelling, dizziness, blepharitis, eye irritation, gastrointestinal symptoms, weakness, blanching of the conjunctiva, abnormal vision, and muscular pain. The following reactions were reported in fewer than 3 percent of patients: crusting of the eyelid, bleeding beneath the conjunctiva, altered taste, insomnia, discharge from the eye, depression, high blood pressure, anxiety, palpitations or irregular heartbeat, dryness of the nose, and fainting.
Cautions & Contraindications
Warnings & Precautions
Although Brimodin ophthalmic solution had little effect on blood pressure in clinical studies, it should be used carefully in patients with severe cardiovascular disease. Caution is also advised when prescribing it for patients with depression, cerebral or coronary insufficiency, Raynaud's phenomenon, orthostatic hypotension, or thromboangiitis obliterans.
Contraindications
Brimonidine Tartrate ophthalmic solution should not be used by anyone who is hypersensitive to Brimonidine Tartrate. It should also be avoided in patients currently on monoamine oxidase (MAO) inhibitor therapy.
Pregnancy & Breastfeeding
Pregnancy: There is no adequate, well-controlled research on the use of this medicine in pregnant women. Animal studies have shown that Brimonidine crosses the placenta and reaches the fetal circulation to a limited extent. For this reason, Brimonidine Tartrate 0.2% eye drops should be used during pregnancy only if the expected benefit to the mother outweighs the possible risk to the unborn child.
Breastfeeding: It is not known whether this medicine passes into human breast milk, though animal studies have shown that Brimonidine Tartrate is excreted in breast milk. Because of this, a decision should be made either to stop breastfeeding or to stop the medicine, weighing how important the treatment is for the mother.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Brimonidine Tartrate below 30°C, in a cool and dry place, and away from light. Keep it out of reach of children. Don't let the dropper tip touch any surface, because that can contaminate the solution. Once you've opened the bottle, don't use it after 30 days.
Drug Interactions
Common questions about Bricoma 0.2%
What is Bricoma 0.2% Ophthalmic Solution?
Bricoma 0.2% Ophthalmic Solution is a medicine that contains Brimonidine Tartrate. It is made by Opsonin Pharma Limited. It belongs to the Drugs for miotics and glaucoma group of medicines.
What is Bricoma used for?
Bricoma is used for: Hypertension, Glaucoma.
What are the side effects of Bricoma?
Adverse events occurred in about 10 to 30 percent of subjects, and in descending order of frequency included dryness of the mouth, redness of the eye, burning and stinging, headache, blurred vision, a sensation of something in the eye, fatigue or drowsiness, conjunctival follicles, ocular allergic reactions, and itching of the eye. Events occurring in about 3 to 9 percent of subjects, again in descending order, included corneal staining or erosion, sensitivity to light, redness of the eyelid, eye ache or pain, dryness of the eye, tearing, upper respiratory symptoms, eyelid swelling, conjunctival swelling, dizziness, blepharitis, eye irritation, gastrointestinal symptoms, weakness, blanching of the conjunctiva, abnormal vision, and muscular pain.
Can I take Bricoma during pregnancy or while breastfeeding?
Pregnancy: There is no adequate, well-controlled research on the use of this medicine in pregnant women. Animal studies have shown that Brimonidine crosses the placenta and reaches the fetal circulation to a limited extent. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Bricoma?
Keep Brimonidine Tartrate below 30°C, in a cool and dry place, and away from light. Keep it out of reach of children.
Can I take other medicines with Bricoma?
Some medicines can interact with Brimonidine Tartrate, for example: Clonidine Hydrochloride. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Bricoma?
Bricoma is a prescription (Rx) medicine. Take it as your doctor advises.