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Other strengths and forms by Monicopharma Limited
Indications & Uses
Binz is indicated for:
Pharmacology
Carbonic anhydrase (CA) is an enzyme present in many tissues throughout the body, including the eye. It catalyses the reversible reaction that hydrates carbon dioxide and dehydrates carbonic acid. By inhibiting carbonic anhydrase in the eye's ciliary processes, the formation of bicarbonate ions is slowed, which in turn reduces sodium and fluid transport and decreases the secretion of aqueous humor. This leads to a lowering of intraocular pressure (IOP).
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Shake the bottle well before each use. Place 1 drop in the affected eye(s) three times a day. This medicine can be used together with other topical eye drops to lower eye pressure, but if more than one eye drop is being used, wait at least ten minutes between each one.
Pediatric Use: For pediatric patients aged 4 weeks to 5 years, the usual dose is 1 drop in the affected eye(s) 2 times a day.
Geriatric Use: No overall differences in safety or effectiveness have been seen between elderly and younger patients.
Side Effects
Blurred vision and a bitter, sour or otherwise unusual taste were the side effects reported most often with Zolopt, affecting roughly 5-10% of patients. Less commonly seen (in under 1% of patients) were blepharitis, dermatitis, dry eye, a foreign body sensation in the eye, headache, eye redness, eye discharge, eye discomfort, keratitis, eye pain and itching. Also reported at this lower frequency were allergic reactions, hair loss, chest pain, conjunctivitis, dizziness, dry mouth, breathlessness, indigestion, eye fatigue, increased muscle tone, keratoconjunctivitis, crusting or a sticky feeling along the eyelid margin, nausea, sore throat, watery eyes and hives.
Cautions & Contraindications
Warnings & Precautions
Zolopt is a sulfonamide, and although it is applied topically, it is absorbed into the bloodstream. Because of this, the same kinds of adverse reactions seen with sulfonamide medicines can also occur with topical use of Zolopt. Severe sulfonamide reactions have, though rarely, proven fatal, including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood disorders. Sensitization can occur whenever a sulfonamide is given again, regardless of how it is administered. If signs of a serious reaction or hypersensitivity appear, Zolopt should be stopped. Since Zolopt and its metabolite are mainly cleared by the kidneys, it is not recommended for patients with renal impairment. Zolopt has not been studied in patients with hepatic impairment, so it should be used with caution in this group.
Contraindications
Contraindicated in patients known to be hypersensitive to any ingredient in this product.
Pregnancy & Breastfeeding
Pregnancy Category C. No adequate, well-controlled studies have been done in pregnant women, so brinzolamide should be used in pregnancy only if the potential benefit to the mother outweighs the potential risk to the unborn baby. The same applies during breastfeeding: it should be used only if the benefit to the mother justifies the potential risk to the baby.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
There are no human data on overdose with Brinzolamide. Still, if too much were taken by mouth, an imbalance of electrolytes could occur, along with a state of acidosis and possibly effects on the nervous system. Serum electrolyte levels (potassium in particular) and blood pH should be monitored.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Brinzolamide at room temperature and away from light. Don't let the dropper tip touch any surface. The contents should preferably not be used more than four weeks after the bottle is first opened. Protect it from freezing.
Common questions about Binz 10 mg
What is Binz 10 mg Eye Drops?
Binz 10 mg Eye Drops is a medicine that contains Brinzolamide. It is made by Monicopharma Limited. It belongs to the Drugs for miotics and glaucoma group of medicines.
What is Binz used for?
Binz is used for: Hypertension, Glaucoma.
What are the side effects of Binz?
Blurred vision and a bitter, sour or otherwise unusual taste were the side effects reported most often with Zolopt, affecting roughly 5-10% of patients. Less commonly seen (in under 1% of patients) were blepharitis, dermatitis, dry eye, a foreign body sensation in the eye, headache, eye redness, eye discharge, eye discomfort, keratitis, eye pain and itching.
Can I take Binz during pregnancy or while breastfeeding?
Pregnancy Category C. No adequate, well-controlled studies have been done in pregnant women, so brinzolamide should be used in pregnancy only if the potential benefit to the mother outweighs the potential risk to the unborn baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Binz?
There are no human data on overdose with Brinzolamide. Still, if too much were taken by mouth, an imbalance of electrolytes could occur, along with a state of acidosis and possibly effects on the nervous system. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Binz?
Keep Brinzolamide at room temperature and away from light. Don't let the dropper tip touch any surface.
Do I need a prescription for Binz?
Binz is a prescription (Rx) medicine. Take it as your doctor advises.