Pricing
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Other strengths and forms by Square Pharmaceuticals PLC, Pabna
Indications & Uses
BetriXa is indicated for:
Pharmacology
Betrixaban is a factor Xa inhibitor. It blocks the active site of factor Xa directly and doesn't need a cofactor, such as Anti-thrombin III, to work. It acts on free factor Xa and also on prothrombinase activity. Because it inhibits factor Xa in this way, Betrixaban lowers thrombin generation (TG). It has no direct effect on platelet aggregation.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Detailed dosing reference is not available yet. Please follow your prescription and consult your pharmacist.
Side Effects
Side-effect information is not available for this brand yet.
Cautions & Contraindications
Warnings & Precautions
Betrixaban can cause bleeding, so any sign or symptom of blood loss needs to be evaluated promptly. Spinal or epidural anesthesia, and spinal or epidural puncture, carry a particular risk. Patients on antithrombotic agents to prevent thromboembolic complications can develop an epidural or spinal hematoma when neuraxial anesthesia (spinal/epidural anesthesia) or a spinal/epidural puncture is used. This can lead to long-term or permanent paralysis. Don't remove an epidural catheter earlier than 72 hours after the last dose of BetriXa. The next BetriXa dose should not be given earlier than 5 hours after the catheter is removed. If a traumatic puncture occurs, delay BetriXa for 72 hours. Severe renal impairment increases the risk of bleeding events. The same is true when betrixaban is taken together with P-gp inhibitors.
Contraindications
Betrixaban should not be given to patients who have active pathological bleeding. It is also not for anyone who has had a severe hypersensitivity reaction to Betrixaban.
Pregnancy & Breastfeeding
Use in Pregnancy: No data exist on the use of Betrixaban in pregnant women. Even so, the treatment is likely to raise the risk of hemorrhage during pregnancy and delivery.
Lactation: No data are available on whether Betrixaban or its metabolites pass into human milk. The effects of the drug on a breastfed infant and on milk production are also not known.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Patients with severe renal impairment: Mild or moderate renal impairment (CrCl>30 mL/min) needs no dose adjustment. When renal impairment is severe (CrCl≥15 to <30 mL/min), the recommended dose of BetriXa is a single starting dose of 80 mg, then 40 mg once daily.
Patients with hepatic impairment: People with mild hepatic impairment need no dose adjustment. Betrixaban should be avoided in moderate to severe hepatic impairment.
Storage
Keep Betrixaban away from light and moisture, and store it below 30°C. Make sure the medicine is kept out of reach of children.
Common questions about BetriXa 40 mg
What is BetriXa 40 mg Capsule?
BetriXa 40 mg Capsule is a medicine that contains Betrixaban. It is made by Square Pharmaceuticals PLC, Pabna. It belongs to the Anti-platelet drugs group of medicines.
What is BetriXa used for?
BetriXa is used for: Deep Vein Thrombosis.
Can I take BetriXa during pregnancy or while breastfeeding?
Use in Pregnancy: No data exist on the use of Betrixaban in pregnant women. Even so, the treatment is likely to raise the risk of hemorrhage during pregnancy and delivery. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store BetriXa?
Keep Betrixaban away from light and moisture, and store it below 30°C. Make sure the medicine is kept out of reach of children.
Is there a cheaper medicine with the same ingredient?
BetriXa is already among the lowest-priced brands of Betrixaban at this strength.
Do I need a prescription for BetriXa?
BetriXa is a prescription (Rx) medicine. Take it as your doctor advises.