Pricing
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Arinet is indicated for:
Pharmacology
Artesunate is converted in the body to its active metabolite, dihydroartemisinin (DHA). DHA's endoperoxide bridge reacts with heme, generating free radicals that inhibit protein and nucleic acid synthesis in Plasmodium parasites at all stages of the erythrocytic cycle. These free radicals can also alkylate parasitic proteins, including a calcium adenosine triphosphatase and EXP1, a glutathione S-transferase.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Artesunate tablets are given by mouth. The doses below are the ones stated for each tablet strength.
For the Artesunate 50 mg tablet, adults take two tablets twice on the first day, then one tablet twice daily for the next four days (4, 2, 2, 2, 2). For ages 1 to 3 years, the course is 3 tablets over 5 days (1, 1⁄2, 1⁄2, 1⁄2, 1⁄2). At 4 to 5 years it is 6 tablets over 5 days (2, 1, 1, 1, 1), and at 6 to 12 years it is 8 tablets over 5 days (3, 2, 1, 1, 1).
For the Artesunate 100 mg tablet, adults take one tablet twice on the first day, then half a tablet twice daily for the next four days (2, 1, 1, 1, 1). Ages 4 to 5 years get 3 tablets over 5 days (1, 1⁄2, 1⁄2, 1⁄2, 1⁄2), and ages 6 to 12 years get 4 tablets over 5 days (1 1⁄2, 1, 1⁄2, 1⁄2, 1⁄2).
Patients older than 12 years should be given the same dose as adults.
To prevent malaria, the dose is two Artesunate 50 mg tablets (or one Artesunate 100 mg tablet) as a single dose once a week. Start one week before entering a malaria-affected area and continue until four weeks after leaving it.
Side Effects
Artex tablets are generally well tolerated. No adverse effects have been reported when Artex is taken at the recommended dose.
Cautions & Contraindications
Warnings & Precautions
Use this tablet with caution in patients who are vomiting severely. For emergency treatment of severe malaria, intravenous or intramuscular injection is preferred. Do not use this medicine without the advice of a registered physician, and do not exceed the recommended dose.
Contraindications
Do not use Artesunate if you have a known allergy to Artemisinin or any of its derivatives, or to any of the inactive ingredients in the product.
Pregnancy & Breastfeeding
A WHO review of the safety of artemisinin derivatives in pregnancy concluded that these drugs should remain available for treating malaria in pregnancy, whatever the trimester. WHO also said that more study is still needed. So Artesunate tablet can be given to pregnant women, especially in the first trimester, if a Registered Physician recommends it.
Like many other drugs, artesunate may pass into breast milk. Because it could harm a nursing baby, breastfeeding should be stopped while the malaria treatment with Artesunate tablet is going on.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Artesunate below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Arinet 50 mg
What is Arinet 50 mg Tablet?
Arinet 50 mg Tablet is a medicine that contains Artesunate. It is made by Alco Pharma Limited. It belongs to the Anti-malarial drugs group of medicines.
What is Arinet used for?
Arinet is used for: Malaria.
What are the side effects of Arinet?
Artex tablets are generally well tolerated. No adverse effects have been reported when Artex is taken at the recommended dose.
Can I take Arinet during pregnancy or while breastfeeding?
A WHO review of the safety of artemisinin derivatives in pregnancy concluded that these drugs should remain available for treating malaria in pregnancy, whatever the trimester. WHO also said that more study is still needed. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Arinet?
Store Artesunate below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Arinet?
Some medicines can interact with Artesunate, for example: Erythromycin, Disopyramide, Terfenadine, Amiodarone Hydrochloride, Quinine Sulphate, Sotalol Hydrochloride. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Arinet is already among the lowest-priced brands of Artesunate at this strength.
Do I need a prescription for Arinet?
Arinet is a prescription (Rx) medicine. Take it as your doctor advises.