Aprodex
Rx300 mg • Eye and Ear Drops
More from Aprodex
Other strengths and forms by Aristopharma Limited
Indications & Uses
Aprodex is indicated for:
Pharmacology
Dexamethasone is a glucocorticoid with anti-inflammatory and anti-allergic effects, and is applied topically to treat inflammation of the eye's anterior segment. It works by inhibiting the enzyme phospholipase A2, which cuts down prostaglandin synthesis, and it also blocks neutrophils from migrating into the inflamed area.
Ciprofloxacin, meanwhile, shows in vitro activity against a broad range of gram-negative and gram-positive organisms and is regarded as the most potent antibacterial among the quinolones. It kills bacteria by interfering with DNA gyrase, an enzyme bacteria need to synthesize their DNA.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
For the eye: 1 drop into the conjunctival sac or sacs every four to six hours. During the first 24 to 48 hours, the dose may be raised to 1 drop every two hours.
For the ear: in children with acute otitis media who have a tympanostomy tube, 4 drops go into the affected ear 2 times daily for 7 days. The same dose and schedule applies to acute otitis externa: 4 drops into the affected ear 2 times daily for 7 days.
Paediatric use: safety and effectiveness in children below 1 year have not been established.
Side Effects
Eye: The most common side effect reported with Ciprofloxacin is a brief burning or discomfort in the eye. Other reactions that have been reported include stinging, redness, itching, conjunctivitis/keratitis, swelling around the eye or face, a feeling that something is in the eye, sensitivity to light, blurred vision, watering, dryness, and eye pain. Dizziness has rarely been reported as well. The steroid component may raise the intraocular pressure (IOP), which can potentially lead to glaucoma, and less often causes optic nerve damage, posterior subcapsular cataract, and delayed wound healing. Ear: The most common side effects are discomfort and pain in the ear. Other reported reactions include irritability, dizziness, and redness (erythema), among others.
Cautions & Contraindications
Warnings & Precautions
Fungal infection of the cornea should be considered as a possibility whenever steroid dosing has continued over a long period, and also in patients with persistent corneal ulceration. Extended use of the antibiotic may result in overgrowth of non-susceptible organisms. Extended use of topical ophthalmic steroids may result in glaucoma, with damage to the optic nerve, defects in visual acuity and fields of vision, and formation of posterior subcapsular cataract. Intraocular pressure should be monitored on a routine basis.
Contraindications
Hypersensitivity to any ingredient in this preparation. It should not be used in cases of herpes simplex or other viral infections of the ear or eye, fungal infections of the ear or eye, or glaucoma, and it is not recommended for newborn babies.
Pregnancy & Breastfeeding
Pregnancy: Well-controlled studies in pregnant women have not been done, so the safety of this drug during pregnancy is not fully established. This Sterile Eye & Ear Drops should be used in pregnancy only if the potential benefit to the mother outweighs the potential risk to the unborn baby.
Breastfeeding: It is not known whether this drug passes into human breast milk. Nursing mothers should therefore use this Sterile Eye & Ear Drops with caution.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Ciprofloxacin + Dexamethasone in a cool, dry place, away from light, and out of the reach of children. Shake the bottle well before each use. Close it tightly straight after every use. Once you have opened it for the first time, use the medicine within 30 days.
Drug Interactions
Common questions about Aprodex 300 mg
What is Aprodex 300 mg Eye and Ear Drops?
Aprodex 300 mg Eye and Ear Drops is a medicine that contains Ciprofloxacin + Dexamethasone. It is made by Aristopharma Limited. It belongs to the Aural steroid & antibiotic combined preparations group of medicines.
What is Aprodex used for?
Aprodex is used for: Bacterial Infection, Otitis Media, Inflammation.
What are the side effects of Aprodex?
Eye: The most common side effect reported with Ciprofloxacin is a brief burning or discomfort in the eye. Other reactions that have been reported include stinging, redness, itching, conjunctivitis/keratitis, swelling around the eye or face, a feeling that something is in the eye, sensitivity to light, blurred vision, watering, dryness, and eye pain.
Can I take Aprodex during pregnancy or while breastfeeding?
Pregnancy: Well-controlled studies in pregnant women have not been done, so the safety of this drug during pregnancy is not fully established. This Sterile Eye & Ear Drops should be used in pregnancy only if the potential benefit to the mother outweighs the potential risk to the unborn baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Aprodex?
Keep Ciprofloxacin + Dexamethasone in a cool, dry place, away from light, and out of the reach of children. Shake the bottle well before each use.
Can I take other medicines with Aprodex?
Some medicines can interact with Ciprofloxacin + Dexamethasone, for example: Ciprofloxacin, Theophylline, Dexamethasone, Caffeine, Cyclosporine, Warfarin Sodium. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Aprodex?
Aprodex is a prescription (Rx) medicine. Take it as your doctor advises.