Antrenex
Rx10 mg/ml • Eye Drops
Indications & Uses
Antrenex is indicated for:
Pharmacology
Oxyphenonium belongs to a class of medicines called anticholinergics (antimuscarinics). It works by blocking the action of acetylcholine, a chemical released by nerves that normally stimulates muscle activity, at receptors found on smooth muscle. Alongside this, it also relaxes smooth muscle directly. Because of these actions, Oxyphenonium is prescribed to treat and prevent muscle spasms in the gastrointestinal tract associated with irritable bowel syndrome. It also slows down the natural propulsive movements of the gut, reduces the secretion of stomach acid, and helps control excessive secretions in the throat, windpipe, and bronchial airways.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Average adult dose is 10 mg (2 tablets), taken 4 times a day for several days. The physician may adjust this dose based on how the patient responds.
Side Effects
Common side effects include a dry mouth, headache, and palpitations.
Cautions & Contraindications
Warnings & Precautions
Use with caution in children and the elderly, and in benign prostatic hyperplasia, acute MI, cardiac failure, hypertension, thyrotoxicosis, pregnancy and lactation, fever, or angle-closure glaucoma.
Contraindications
Oxyphenonium bromide should not be used in people with glaucoma, or with obstruction of the urinary tract (such as bladder neck obstruction from an enlarged prostate). It is also unsuitable for those with obstructive conditions of the gastrointestinal tract, such as achalasia, paralytic ileus, or pyloroduodenal stenosis, and for elderly or debilitated patients with reduced intestinal tone. It should be avoided in patients with unstable cardiovascular status accompanied by acute hemorrhage, as well as in severe ulcerative colitis or toxic megacolon complicating ulcerative colitis. Additional contraindications include myasthenia gravis and known hypersensitivity to the drug.
Pregnancy & Breastfeeding
Either studies in animals have shown possible harm to the developing baby (birth defects or pregnancy loss), or well-controlled studies in pregnant women simply haven't been done, or the necessary studies in either women or animals aren't available. Because of this, Oxyphenonium Bromide should be used during pregnancy only if the expected benefit to the mother outweighs the possible risk to the baby.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
An overdose of Oxyphenonium Bromide is treated the same way as an atropine overdose.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Oxyphenonium Bromide below 30°C, away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Antrenex 10 mg/ml
What is Antrenex 10 mg/ml Eye Drops?
Antrenex 10 mg/ml Eye Drops is a medicine that contains Oxyphenonium Bromide. It is made by OSL Pharma Ltd. It belongs to the Anticholinergics (antimuscarinics)/ Anti-spasmodics group of medicines.
What is Antrenex used for?
Antrenex is used for: Pain, Peptic Ulcer, Constipation, Cancer.
What are the side effects of Antrenex?
Common side effects include a dry mouth, headache, and palpitations.
Can I take Antrenex during pregnancy or while breastfeeding?
Either studies in animals have shown possible harm to the developing baby (birth defects or pregnancy loss), or well-controlled studies in pregnant women simply haven't been done, or the necessary studies in either women or animals aren't available. Because of this, Oxyphenonium Bromide should be used during pregnancy only if the expected benefit to the mother outweighs the possible risk to the baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Antrenex?
An overdose of Oxyphenonium Bromide is treated the same way as an atropine overdose. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Antrenex?
Store Oxyphenonium Bromide below 30°C, away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Antrenex?
Some medicines can interact with Oxyphenonium Bromide, for example: Amantadine Hydrochloride. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Antrenex?
Antrenex is a prescription (Rx) medicine. Take it as your doctor advises.