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Same active ingredient — pay up to 19% less
These brands contain the same active ingredient (Losartan Potassium). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Anin
Other strengths and forms by Delta Pharma PLC.
Indications & Uses
Anin is indicated for:
Pharmacology
Losartan Potassium is the first non-peptide, orally active angiotensin II receptor blocker. It binds to the AT1 receptor found in many tissues (such as vascular smooth muscle, the adrenal gland, kidneys and heart) and reduces several important biological actions, including vasoconstriction and the release of aldosterone, which are responsible for hypertension.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The usual starting and maintenance dose for most patients is 50 mg once daily. If 50 mg once daily does not lower blood pressure enough, 25 mg twice daily is recommended before the dose is increased. For patients with intravascular volume depletion (for example, those treated with high-dose diuretics), a starting dose of 25 mg once daily should be considered. Losartan Potassium can be given once or twice daily. The total daily dose ranges from 25 mg to 100 mg.
Patients up to 75 years: No initial dosage adjustment is necessary for this group of patients.
Patients over 75 years: There is currently limited clinical experience in this group; a lower starting dose of 25 mg once daily is recommended.
Side Effects
Side effects of Losart-P are generally mild and short-lived. The most common are dizziness, diarrhoea, nasal congestion, cough and upper respiratory tract infection. Less common side effects include fatigue, oedema (swelling), abdominal pain, chest pain, nausea, headache and pharyngitis (sore throat).
Cautions & Contraindications
Warnings & Precautions
If Losart-P is used in the second and third trimesters of pregnancy, it reduces the baby's kidney function and raises the risk of illness and death in the fetus and the newborn. In patients who are low in body fluid volume, for example those on high-dose diuretics, symptomatic hypotension may occur. The plasma concentration of Losart-P is much higher in patients with cirrhosis. Changes in kidney function, including renal failure, have been reported in patients who already have impaired kidney function.
Contraindications
Losartan Potassium must not be used during pregnancy, or in anyone who is hypersensitive (allergic) to losartan or to any other ingredient of this product. It also must not be given together with aliskiren to patients who have diabetes.
Pregnancy & Breastfeeding
Pregnancy Category D. If Losartan Potassium is taken during the second or third trimester of pregnancy, the risk to the baby increases. It is not known whether Losartan Potassium passes into human breast milk. Since many drugs do pass into breast milk, and because of the possible risk of adverse effects on a nursing infant, a decision should be made whether to stop breastfeeding or stop the medicine, weighing how important the drug is to the mother.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Losartan Potassium doesn't need a lower starting dose in patients with mild renal impairment (creatinine clearance 20 to 50 ml/min). For moderate to severe renal impairment (creatinine clearance <20 ml/min), or for patients on dialysis, a lower starting dose of 25 mg (one Losartan Potassium-50 tablet) once daily is recommended.
A very small proportion of patients have intravascular volume depletion, for example those treated with high-dose diuretics. For them, the recommended starting dose is also 25 mg (one Losartan Potassium-50 tablet) once daily.
In patients with a history of hepatic impairment, a lower dose should be considered. Losartan Potassium may be given with other antihypertensive agents, and it may be taken with or without food.
Losart is contra-indicated in pregnancy and in patients who are hypersensitive to losartan.
Pharmacokinetic data show significantly increased plasma concentrations of losartan in cirrhotic patients, so a lower dose should be considered for patients with a history of hepatic impairment. Other drugs that affect the renin-angiotensin-aldosterone system may increase blood urea and serum creatinine in patients with bilateral renal artery stenosis of the artery to a solitary kidney. Similar effects have been reported with losartan, and these changes in renal function may be reversible when therapy is stopped. Losart should not be used with potassium-sparing diuretics.
Storage
Store Losartan Potassium in a dry place, away from light and heat. Keep it out of the reach of children.
Drug Interactions
Common questions about Anin 50 mg
What is Anin 50 mg Tablet?
Anin 50 mg Tablet is a medicine that contains Losartan Potassium. It is made by Delta Pharma PLC. It belongs to the Angiotensin-ll receptor blocker group of medicines.
What is Anin used for?
Anin is used for: Hypertension.
What are the side effects of Anin?
Side effects of Losart-P are generally mild and short-lived. The most common are dizziness, diarrhoea, nasal congestion, cough and upper respiratory tract infection.
Can I take Anin during pregnancy or while breastfeeding?
Pregnancy Category D. If Losartan Potassium is taken during the second or third trimester of pregnancy, the risk to the baby increases. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Anin?
Store Losartan Potassium in a dry place, away from light and heat. Keep it out of the reach of children.
Can I take other medicines with Anin?
Some medicines can interact with Losartan Potassium, for example: Hydrochlorothiazide, Fluconazole, Spironolactone, Rifampicin, Indomethacin, Telmisartan + Hydrochlorothiazide. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Cozaril by Hallmark Pharmaceuticals Ltd. has the same ingredient and strength for ৳4.03 per unit, compared with ৳5.00 for Anin. Ask your doctor or pharmacist before switching.
Do I need a prescription for Anin?
Anin is a prescription (Rx) medicine. Take it as your doctor advises.