Pricing
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Indications & Uses
Hydrocortisone + Lidocaine ano-rectal cream is used to relieve itching, pain, soreness and discomfort caused by hemorrhoids, anal fissures, anal pruritus and similar conditions of the anal area. It works in two ways: hydrocortisone reduces inflammation and lidocaine numbs the area.
Pharmacology
Hydrocortisone is a corticosteroid, used for its anti-inflammatory and immunosuppressive effects. It works against inflammation by suppressing the migration of polymorphonuclear leukocytes and by reversing increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency.
Lidocaine is an amide type local anesthesia. It stabilises the neuronal membrane and inhibits Na ion movements, which are needed for the conduction of impulses. In the heart, lidocaine reduces depolarisation of the ventricles during diastole, and it reduces automaticity in the His-Purkinje system. The duration of the action potential and the effective refractory period are also reduced.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Apply the hydrocortisone and lidocaine cream to the affected area twice a day, or as your physician directs. Gently insert the applicator tip into the anal area, which means the areas of discomfort and the anal opening. Don't push the applicator or the tube fully into the anus or rectum.
Pediatric use: safety and efficacy in pediatric patients have not been established.
Side Effects
Anacaine Cream can cause a short-lived stinging or burning feeling during application or just after it, mostly where the skin is open. The skin may also turn lighter in colour (blanching) or red (erythema) for a short time.
Cautions & Contraindications
Warnings & Precautions
If an infection develops, stop using Hydrocortisone + Lidocaine. When it's applied over large areas, some of the medicine can be absorbed into the body and may suppress the hypothalamic-pituitary-adrenal (HPA) axis. So don't use it for long periods, and don't use it under occlusive dressings. Take care in people with impaired hepatic function and in patients who are taking class I antiarrhythmics.
Contraindications
Don't use Hydrocortisone + Lidocaine if you have ever had an allergic reaction to any of its ingredients.
Pregnancy & Breastfeeding
Hydrocortisone + Lidocaine is Pregnancy Category C. There are no adequate and well-controlled studies in pregnant women. It is also not known whether the drug passes into human milk.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Hydrocortisone + Lidocaine at a controlled room temperature of 15°C to 30°C, and don't let it freeze. Keep it out of the reach of children.
Drug Interactions
Common questions about Anacaine HC 0.5% + 3%
What is Anacaine HC 0.5% + 3% Cream?
Anacaine HC 0.5% + 3% Cream is a medicine that contains Hydrocortisone + Lidocaine. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Drugs used in Ano-rectal region group of medicines.
What is Anacaine HC used for?
Hydrocortisone + Lidocaine ano-rectal cream is used to relieve itching, pain, soreness and discomfort caused by hemorrhoids, anal fissures, anal pruritus and similar conditions of the anal area. It works in two ways: hydrocortisone reduces inflammation and lidocaine numbs the area.
What are the side effects of Anacaine HC?
Anacaine Cream can cause a short-lived stinging or burning feeling during application or just after it, mostly where the skin is open. The skin may also turn lighter in colour (blanching) or red (erythema) for a short time.
Can I take Anacaine HC during pregnancy or while breastfeeding?
Hydrocortisone + Lidocaine is Pregnancy Category C. There are no adequate and well-controlled studies in pregnant women. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Anacaine HC?
Keep Hydrocortisone + Lidocaine at a controlled room temperature of 15°C to 30°C, and don't let it freeze. Keep it out of the reach of children.
Can I take other medicines with Anacaine HC?
Some medicines can interact with Hydrocortisone + Lidocaine, for example: Cyclosporine, Disopyramide, Procainamide Hydrochloride. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Anacaine HC?
Anacaine HC is a prescription (Rx) medicine. Take it as your doctor advises.