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Same active ingredient — pay up to 2% less
These brands contain the same active ingredient (Cefadroxil Monohydrate). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Adocil
Other strengths and forms by Kemiko Pharmaceuticals Ltd.
Indications & Uses
Adocil is indicated for:
Pharmacology
Cefadroxil works by attaching to 1 or more of the penicillin-binding proteins (PBPs) in bacteria. This stops the final transpeptidation step of peptidoglycan synthesis in the bacterial cell wall. With that step blocked, the cell wall can't be built or put together properly, and the bacterial cell dies.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Detailed dosing reference is not available yet. Please follow your prescription and consult your pharmacist.
Side Effects
Cefadroxil can cause side effects in different parts of the body. Vaginal mycoses and thrush are uncommon. In the blood and lymphatic system, eosinophilia, thrombocytopenia, leucopenia, neutropenia and agranulocytosis are rare, and haemolytic anemia is very rare. For the immune system, serum sickness-like reactions are rare, while an immediate allergic reaction (anaphylactic shock) is very rare. Very rare effects on the nervous system are headache, sleeplessness, dizziness and nervousness. Stomach and gut effects are common and include nausea, vomiting, diarrhoea, dyspepsia, abdominal pain and glossitis. Pseudomenbranous colitis is very rare. In the liver and bile system, cholestase and idiosyncratic hepatic failure are rare. Skin effects such as pruritus, rash, allergic exanthema and urticaria are common. Stevens Johnson syndrom and erythema multiforma are very rare. Arthralgia is a rare muscle and joint effect, and interstitial nephritis is a rare effect on the kidneys and urinary system. Fever is rare, and fatigue is very rare.
Cautions & Contraindications
Warnings & Precautions
Cefadroxil Monohydrate binds to cholestyramine, and this can lower how much cefadroxil the body absorbs and uses (its bioavailability). Probenecid works the other way. When it's given together with cefadroxil, the kidneys clear less of the cefadroxil, so the plasma concentrations of cefadroxil may go up.
Contraindications
Cefadroxil must not be given to patients with a history of hypersensitivity to any of the cephalosporins. The same applies to patients with a history of severe reactions to penicillins or to any other beta lactam drugs. It should not be combined with bacteriostatic antibiotics (e.g. tetracycline, erythromycin, sulfonamides, chloramphenicol), because an antagonistic effect is possible. Combining it with aminoglycoside antibiotics, polymyxin B, colistin or high-dose loop diuretics should also be avoided, since these combinations can potentiate nephrotoxic effects. It does not penetrate the CSF and is not indicated for the treatment of meningitis. Penicillin is the first drug of choice for treating Streptococcus pyogenes and for preventing rheumatic fever, and the data for cefadroxil are not sufficiently substantial for prophylaxis therapy. Special caution is needed in patients with a history of severe allergies or asthma. In patients with a history of non severe hypersensitivity to penicillins, or to other non-cephalosporin beta-lactam drugs, it should also be used with special caution. Caution is necessary in renal impairment too, and the dosage must be adjusted according to the grade of renal impairment. Use it carefully in patients with a history of gastro-intestinal disturbances, particularly colitis. Diarrhoea may impair the resorption of other medicaments and so reduce how well they work. Stop treatment at once if allergic reactions occur (urticaria, exanthema, pruritus, fall of blood pressure and increased heart rate, respiratory disturbances, collapse, etc.) and take suitable countermeasures (sympathomimetics, corticosteroids and/or antihistaminics). On prolonged use in particular, frequent checks on the blood count and regular hepatic and renal function tests are advisable. Superinfections with fungi (e.g. candida) can occur on prolonged treatment. If diarrhoea is severe and persistent, antibiotic-associated pseudomembranous colitis should be considered. In that case cefadroxil must be discontinued immediately and a suitable therapy started. The result of the Coombs' test can be transiently positive during or after treatment, and this also applies to Coombs' tests carried out in newborns whose mothers received treatment with cephalosporins before delivery. Urinary sugar should be determined enzymatically (e.g. with test strips) during treatment, since reduction tests can furnish falsely elevated values.
Pregnancy & Breastfeeding
Animal studies and clinical experience have shown no evidence that cefadroxil causes birth defects, but its safe use in pregnancy has not been established. Cefadroxil passes into breast milk in low concentrations. Even so, the infant may develop sensitisation or diarrhoea, or fungi may colonise the infant's mucosa. For these reasons, cefadroxil should be used very strictly during pregnancy and in breastfeeding mothers.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
There are no clinical reports of cefadroxil overdose so far. But going by experience with other cephalosporins, a few symptoms are possible: nausea, hallucinations, hyperreflexia, extrapyramidal symptoms, clouded consciousness, and even coma and renal functional impairment.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Cefadroxil Monohydrate in a dry place, away from light and heat. Keep it out of the reach of children.
Common questions about Adocil 500 mg
What is Adocil 500 mg Capsule?
Adocil 500 mg Capsule is a medicine that contains Cefadroxil Monohydrate. It is made by Kemiko Pharmaceuticals Ltd. It belongs to the First generation cephalosporins group of medicines.
What is Adocil used for?
Adocil is used for: Pneumonia, Pharyngitis, Tonsillitis, Urinary Tract Infection, Skin and Soft Tissue Infection.
What are the side effects of Adocil?
Cefadroxil can cause side effects in different parts of the body. Vaginal mycoses and thrush are uncommon.
Can I take Adocil during pregnancy or while breastfeeding?
Animal studies and clinical experience have shown no evidence that cefadroxil causes birth defects, but its safe use in pregnancy has not been established. Cefadroxil passes into breast milk in low concentrations. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Adocil?
There are no clinical reports of cefadroxil overdose so far. But going by experience with other cephalosporins, a few symptoms are possible: nausea, hallucinations, hyperreflexia, extrapyramidal symptoms, clouded consciousness, and even coma and renal functional impairment. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Adocil?
Store Cefadroxil Monohydrate in a dry place, away from light and heat. Keep it out of the reach of children.
Is there a cheaper medicine with the same ingredient?
Sefadol by Techno Drugs Ltd., Satipara, Narshingdi has the same ingredient and strength for ৳11.74 per unit, compared with ৳12.04 for Adocil. Ask your doctor or pharmacist before switching.
Do I need a prescription for Adocil?
Adocil is a prescription (Rx) medicine. Take it as your doctor advises.