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Rx6 mg/2 ml • IV Injection
More from Adecard
Other strengths and forms by Popular Pharmaceuticals PLC
Indications & Uses
Intravenous Adecard is used to convert paroxysmal supraventricular tachycardia (PSVT) back to a normal sinus rhythm, including PSVT associated with accessory bypass tracts, as seen in Wolff-Parkinson-White syndrome.
Pharmacology
Adenosine injection comes as a sterile, non-pyrogenic solution meant to be given as a fast intravenous bolus. It works by slowing conduction through the A-V node, which can break the reentry circuits that pass through this node and, in doing so, help restore a normal sinus rhythm in patients with paroxysmal supraventricular tachycardia.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adult: Initial dose is 6 mg given as a rapid IV bolus, administered over 1 to 2 seconds. Repeat administration: if the first dose does not eliminate the supraventricular tachycardia within 1 to 2 minutes, 12 mg should be given as a rapid intravenous bolus. This 12 mg dose may be repeated a second time if required. Pediatric: the dosages used in neonates, infants, children and adolescents were equivalent to those given to adults on a weight basis. Body weight below 50 kg: Initial dose is 0.05 to 0.1 mg/kg as a rapid IV bolus given either centrally or peripherally. A saline flush should follow. Body weight above 50 kg: the adult dose is recommended. Doses greater than 12 mg are not recommended for adult and pediatric patients. Repeat administration: if conversion of PSVT does not occur within 1 to 2 minutes, additional bolus injections of adenosine can be given at incrementally higher doses, increasing the amount by 0.05 to 0.1 mg/kg. A saline flush should follow. This process should continue until sinus rhythm is established or a maximum single dose of 0.3 mg/kg is used.
Side Effects
Cardiovascular effects may include facial flushing, headache, sweating, palpitations, chest pain, and low blood pressure. Respiratory effects may include shortness of breath, chest pressure, rapid breathing, and a sensation of pressure in the head. Central nervous system effects may include lightheadedness, dizziness, tingling or numbness in the arms, a feeling of apprehension, blurred vision, a burning sensation, heaviness in the arms, and pain in the neck and back. Gastrointestinal effects may include nausea, a metallic taste, tightness in the throat, and a sense of pressure in the groin. In post-marketing experience with Adecard, prolonged asystole, ventricular tachycardia, ventricular fibrillation, a transient rise in blood pressure, slow heart rate, low blood pressure, atrial fibrillation, and bronchospasm have been reported in association with its use.
Cautions & Contraindications
Contraindications
Intravenous Adenosine should not be used in patients with second or third degree A V block, unless they have a functioning artificial pacemaker. It should also be avoided in patients with sinus node disease, such as sick sinus syndrome or symptomatic bradycardia, again unless a functioning artificial pacemaker is in place. It is also contraindicated in anyone with a known hypersensitivity to Adenosine.
Pregnancy & Breastfeeding
Pregnancy category: US FDA category C. In animal studies, adenosine has been shown to harm the fetus, and there are no adequate, well-controlled studies in pregnant women. Even so, its potential benefits may justify use during pregnancy despite the possible risks.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Adenosine has a half-life of less than 10 seconds, so its adverse effects usually clear up quickly on their own. If an adverse effect does last longer, treatment should be individualized and aimed at that particular effect. Methylxanthines such as Caffeine and Theophylline are competitive antagonists of Adenosine.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Adenosine in a cool, dry place, away from light, and out of reach of children. Don't put it in the refrigerator, because crystals may form. If crystals have formed, warm the solution to room temperature to dissolve them. The solution must be clear when you use it.
Drug Interactions
Common questions about Adecard 6 mg/2 ml
What is Adecard 6 mg/2 ml IV Injection?
Adecard 6 mg/2 ml IV Injection is a medicine that contains Adenosine. It is made by Popular Pharmaceuticals PLC. It belongs to the Paroxysmal supraventricular tachycardia (PSVT) group of medicines.
What is Adecard used for?
Intravenous Adecard is used to convert paroxysmal supraventricular tachycardia (PSVT) back to a normal sinus rhythm, including PSVT associated with accessory bypass tracts, as seen in Wolff-Parkinson-White syndrome.
What are the side effects of Adecard?
Cardiovascular effects may include facial flushing, headache, sweating, palpitations, chest pain, and low blood pressure. Respiratory effects may include shortness of breath, chest pressure, rapid breathing, and a sensation of pressure in the head.
Can I take Adecard during pregnancy or while breastfeeding?
Pregnancy category: US FDA category C. In animal studies, adenosine has been shown to harm the fetus, and there are no adequate, well-controlled studies in pregnant women. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Adecard?
Adenosine has a half-life of less than 10 seconds, so its adverse effects usually clear up quickly on their own. If an adverse effect does last longer, treatment should be individualized and aimed at that particular effect. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Adecard?
Keep Adenosine in a cool, dry place, away from light, and out of reach of children. Don't put it in the refrigerator, because crystals may form.
Can I take other medicines with Adecard?
Some medicines can interact with Adenosine, for example: Theophylline, Digoxin, Caffeine, Fludarabine Phosphate, Verapamil Hydrochloride, Dipyridamole. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Adecard?
Adecard is a prescription (Rx) medicine. Take it as your doctor advises.