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These brands contain the same active ingredient (Beta carotene + Vitamin C + Vitamin E). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Each tablet of Beta carotene + Vitamin C + Vitamin E contains three antioxidants, namely Vitamin A, Vitamin C and Vitamin E. These have been linked with reduced risks of cardiovascular diseases in humans, and all three have also been linked with reduced risks of cataract. Supplementation with Vitamin E has been shown to reduce the susceptibility of blood lipoproteins (the proteins that carry cholesterol in the blood) to oxidation, which is the major causative factor in the formation of atheromata in the walls of blood vessels. Vitamin E also helps protect the immune system, and so helps the body combat infection and chronic diseases. It may also be of value in reversing the age-related trend toward decreased competence of the immune system, as well as other age-related degenerative changes. Vitamin C plays an important part in the body's response to stress, and it is important in the defence against infection. It has some anti-inflammatory activity and protects cells against oxidative damage to essential molecules. Vitamin C also increases iron absorption. The primary role of Vitamin E is the prevention of oxidation of polyunsaturated fatty acids. It reacts with free radicals, which are the cause of oxidative damage to cell membranes, and it does this without forming another free radical in the process.
Pharmacology
The beta carotene in this tablet is converted to vitamin A (retinol) when the body needs it. Retinol has several biochemical functions, for example in the retina, in growth, in tissue differentiation and in the immune response. It also has some anti-cancer activity.
Vitamin C is the most powerful reducing agent known to be present in living tissues. A lack of vitamin C causes scurvy. It acts as a cofactor in numerous biological processes. Vitamin C and molecular oxygen are essential for converting proline to hydroxyproline and dopamine to noradrenaline. Vitamin C is also essential for making the adrenal steroid hormones. It is important in the defence against infection, and studies show that it is needed for the normal functioning of T-lymphocytes and leukocytes. Ascorbic acid has some anti-inflammatory activity and protects cells against oxidation of essential molecules. In high doses (1 to 2 g daily), it increases iron absorption.
Vitamin E seems to work as a defence against oxidative stress and lipid peroxidation. In most cell membranes there is one molecule of tocopherol for every 1000 lipid molecules. Tocopherol mops up peroxide radicals, and then it needs a supply of reduced hydrogen to restore the steady-state situation. Ascorbic acid or reduced glutathione usually supplies this.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
You take this beta carotene, vitamin C and vitamin E antioxidant tablet by mouth. For adults the dose is 1 tablet daily, or whatever the doctor has prescribed.
Side Effects
Loose stools may occasionally occur during treatment with beta carotene, and the skin can take on a slightly yellow colour. Beta carotene is converted to vitamin A, and the toxic effects of vitamin A that are seen are normally reversible. An irreversible toxic effect is effectively unknown. Chronic overdosage can lead to peeling and redness of the skin, disturbed hair growth, loss of appetite and sickness. Vitamin C is usually well tolerated. Large doses are reported to cause diarrhoea and other gastro-intestinal disturbances. It has also been stated that doses may result in hyperoxaluria and the formation of renal calcium oxalate calculi, so it should be given with care to patients with hyperoxaluria. Vitamin E is usually well tolerated too. Large doses may cause diarrhoea, abdominal pain and other gastro-intestinal disturbances, and have also been reported to cause fatigue and weakness.
Cautions & Contraindications
Warnings & Precautions
There's some evidence that beta carotene may harm heavy smokers and alcoholics, so take care when this combination is used in these people. Vitamin C should be given with caution to patients with hyperoxaluria. Vitamin E needs caution too in patients who are taking anticoagulant drugs, because it may increase the anticoagulant activity of those drugs.
Contraindications
The body converts beta carotene to Vitamin A only when it needs to. Even so, high doses of Vitamin A should be avoided in pregnancy because of possible teratogenic effects. People who are hypersensitive to retinol should not take this preparation, though such cases are occasional. Vitamin C in megadoses is contraindicated for patients with hyperoxaluria. A pregnant woman who takes more than 5 gm of ascorbate daily may suffer fetal abortion. Higher doses of Vitamin C have also been reported to cause failure of conception. For Vitamin E, there is no absolute contraindication.
Pregnancy & Breastfeeding
Vitamin A (retinol): High doses should not be given in pregnancy. Mothers who are breastfeeding are also best off avoiding high doses of retinol.
Vitamin C: Normal doses are safe for pregnant women, but a daily intake of 5 g or more has been reported to cause abortion. It can be taken safely while breastfeeding.
Vitamin E: The normally recommended dose may be used in pregnancy, but the safety of high-dose therapy has not been established. There appears to be no contraindication to breastfeeding for mothers taking the normally recommended dose.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store this medicine below 30°C, away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about ABC 6 mg+200 mg+50 mg
What is ABC 6 mg+200 mg+50 mg Tablet?
ABC 6 mg+200 mg+50 mg Tablet is a medicine that contains Beta carotene + Vitamin C + Vitamin E. It is made by Union Pharmaceuticals Ltd. It belongs to the Anti-oxidant Multivitamin preparations group of medicines.
What is ABC used for?
Each tablet of Beta carotene + Vitamin C + Vitamin E contains three antioxidants, namely Vitamin A, Vitamin C and Vitamin E. These have been linked with reduced risks of cardiovascular diseases in humans, and all three have also been linked with reduced risks of cataract.
What are the side effects of ABC?
Loose stools may occasionally occur during treatment with beta carotene, and the skin can take on a slightly yellow colour. Beta carotene is converted to vitamin A, and the toxic effects of vitamin A that are seen are normally reversible.
Can I take ABC during pregnancy or while breastfeeding?
Vitamin A (retinol): High doses should not be given in pregnancy. Mothers who are breastfeeding are also best off avoiding high doses of retinol. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store ABC?
Store this medicine below 30°C, away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with ABC?
Some medicines can interact with Beta carotene + Vitamin C + Vitamin E, for example: Erythromycin, Aminophylline, Sodium Bicarbonate, Chloramphenicol, Paracetamol, Nitrofurantoin. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Eba by Apex Pharma Ltd. has the same ingredient and strength for ৳2.25 per unit, compared with ৳2.50 for ABC. Ask your doctor or pharmacist before switching.
Do I need a prescription for ABC?
ABC is a prescription (Rx) medicine. Take it as your doctor advises.