Indications & Uses
Pharmacology
Roxithromycin works by attaching to the 50s subunit of the bacterial ribosome, and this binding does not reverse. In doing so, it interferes with the transpeptidation and translocation steps that susceptible bacteria need to build proteins. Protein synthesis is thereby blocked, and the bacteria's growth is slowed as a result.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adult dose: The usual adult dose is one 300 mg tablet once daily, or one 150 mg tablet twice a day, continued for at least two days after symptoms have resolved. A normal course of treatment lasts between 5 and 10 days. Roxithromycin is best taken on an empty stomach. In severe hepatic impairment, the dose is 150 mg once daily.
Pediatric dose: The dose for children is 2.5 to 5 mg/kg of body weight twice a day. The following general guidelines may be followed: children weighing 6 to 11 kg, 25 mg of Roxithromycin every 12 hours; 12 to 23 kg, 50 mg every 12 hours; 24 to 40 kg, 100 mg every 12 hours. A normal course of treatment lasts between 5 and 10 days.
Side Effects
Ryth is well tolerated by patients of all age groups. Fewer than 4% of those treated report side effects, most commonly nausea, abdominal pain, diarrhoea and a hypersensitivity rash. Other reported side effects include vomiting, dizziness, headache, itching (pruritus), indigestion (dyspepsia), flatulence, ringing in the ears (tinnitus), vertigo and constipation. These are generally minor and do not usually require stopping treatment.
Cautions & Contraindications
Warnings & Precautions
Ryth should not be given to patients with a known hypersensitivity to the drug. In patients with liver disease, the dose of Ryth should not exceed 150 mg twice daily.
Contraindications
Roxithromycin must not be given together with ergotamine or its derivatives, as the combination may trigger arterial spasm and severe ischaemia.
Pregnancy & Breastfeeding
Pregnancy: Safety in pregnancy has not been established for Roxithromycin.
Breastfeeding: Small amounts pass into breast milk, but this has not been shown to cause adverse effects in breastfed infants.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Drug Interactions
Common questions about A Rox 50 mg
What is A Rox 50 mg Powder For Suspension?
A Rox 50 mg Powder For Suspension is a medicine that contains Roxithromycin. It is made by Ambee Pharmaceuticals Ltd. It belongs to the Macrolides group of medicines.
What is A Rox used for?
A Rox is used for: Chronic Obstructive Pulmonary Disease, Pneumonia, Bronchitis, Sinusitis, Pharyngitis, Tonsillitis, Skin and Soft Tissue Infection, Otitis Media, Eczema.
What are the side effects of A Rox?
Ryth is well tolerated by patients of all age groups. Fewer than 4% of those treated report side effects, most commonly nausea, abdominal pain, diarrhoea and a hypersensitivity rash.
Can I take A Rox during pregnancy or while breastfeeding?
Pregnancy: Safety in pregnancy has not been established for Roxithromycin. Breastfeeding: Small amounts pass into breast milk, but this has not been shown to cause adverse effects in breastfed infants. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Can I take other medicines with A Rox?
Some medicines can interact with Roxithromycin, for example: Dienogest, Carbamazepine, Theophylline, Warfarin Sodium. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for A Rox?
A Rox is a prescription (Rx) medicine. Take it as your doctor advises.