Indications & Uses
Winclas is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Clean the affected area gently then apply a thin uniform layer (approximately 1 gm) of Clascoterone cream twice per day in the morning and evening to the affected area. Avoid accidental transfer of Clascoterone cream into eyes, mouth, or other mucous membranes. If contact with mucous membranes occurs, this should be rinsed thoroughly with water or as directed by physician.Use in Children and Adolescents: Safety and effectiveness of Clascoterone cream for the topical treatment of acne vulgaris have not been established in pediatric patients under 12 years of age
Side Effects
Most common adverse reactions occurring in 7% to 12% of patients are erythema/ reddening, pruritus, and scaling/dryness. Additionally, >3% of patients may suffer from edema, stinging and burning.Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.In two identical multicenter, randomized, double-blind, vehicle-controlled trials, 1421 subjects 12 years and older with facial acne vulgaris applied Clascon cream or vehicle twice daily for 12 weeks. Overall, 62% of the subjects were female, and 38% were male, 91% of the patients were Caucasian, and the mean age was 19.7 years.Local skin reactions (edema, erythema/redness, pruritus, scaling/dryness, skin atrophy, stinging/burning, striae rubrea, telangiectasia) were observed during the 12-week treatment and occurred in a similar percentage of subjects treated with vehicle.
Cautions & Contraindications
Warnings & Precautions
Local Irritation: Pruritus, burning, skin redness or peeling may be experienced with Clascon cream. If these effects occur discontinue or reduce the frequency of application of Clascon cream. Hypothalamic-pituitary-adrenal (HPA) axis suppression may occur during or after treatment with Clascon. Paediatric patients may be more susceptible to systemic toxicity. Hyperkalemia: Elevated potassium levels are observed in some subjects during the clinical trials
Contraindications
Data of contraindication of clascoterone cream in not available.