Save on this medicine
Other brands with the same active ingredient
These brands contain the same active ingredient (Vonoprazan). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Venocid- 10 is indicated for:
Pharmacology
Vonoprazan is a potassium competitive acid blocker (P-CAB) and does not require activation by acid. It inhibits H+, K+-ATPase in a reversible and potassium-competitive manner. Vonoprazan has a strong basicity and resides on the acid production site of gastric parietal cells for a long time, thereby inhibiting gastric acid production. Vonoprazan exerts a strong inhibitory effect on formation of mucosal damage in upper part of the gastrointestinal tract.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dosage Gastric ulcer and duodenal ulcer: The usual adult dose for oral use is 20 mg of Vonoprazan administered orally once daily an 8-week treatment for gastric ulcer and a 6-week treatment for duodenal ulcer. Reflux esophagitis: The usual adult dose for oral use is 20 mg of Vonoprazan administered once daily for a total of 4 weeks of treatment. If that dosing proves insufficient, the administration should be extended, but for no longer than 8 weeks of treatment. For the maintenance therapy of reflux esophagitis showing recurrence and recrudescence, the dose for oral use is 10mg of Vonoprazan once daily. However, when the efficacy is inadequate, the dosage may be increase up to 20 mg of Vonoprazan once daily.Prevention of recurrence of gastric or duodenal ulcer during low-dose aspirin administration: The usual adult dose is one tablet of 10 mg of Vonoprazan administered orally once daily.Prevention of recurrence of gastric or duodenal ulcer during non-steroidal anti-inflammatory drug (NSAID): administration The usual adult dose is one tablet of 10 mg of Vonoprazan administered orally once daily.Adjunct to Helicobacter pylori eradication: For adults, the following three-drug regimen should be administered orally at the same time twice daily for seven days: 20 mg of Vonoprazan, 750 mg of amoxicillin hydrate and 200 mg of clarithromycin. The dose of clarithromycin may be increased as clinically warranted. However, dosage should not exceed 400 mg twice daily.If Helicobacter pylori eradication with a three-drug regimen comprising a proton pump inhibitor, amoxicillin hydrate and clarithromycin has been unsuccessful, as an alternative treatment, adults should be administered the following three drugs orally twice daily for seven days: 20 mg of Vonoprazan, 750 mg of amoxicillin hydrate and 250 mg of metronidazole.
Side Effects
Following side effects have been reported with the use of Vonolend: Diarrhea, constipation, drug hypersensitivity (including anaphylactic shock), drug eruption, urticaria, hepatotoxicity, jaundice, rash, nausea, abdominal distension, gamma-glutamyl transferase increased, AST increased, Liver function test abnormal, ALT increased, ALP increased, LDH increased, y-GPT increased, edema and eosinophilia
Cautions & Contraindications
Warnings & Precautions
At the treatment, the course of the disease should closely be observed and the minimum therapeutic necessity should be used according to the disease condition. In the long-term, treatment with Vonolend, close observation by such means as endoscopy should be made.In the maintenance of healing of reflux esophagitis, Vonolend should be administered only to the patients who repeat recurrence and recrudescence of the condition. Administration to the patients who do not necessitate maintenance of healing should be avoided.When the healing is maintained over a long period and when there is no risk of recurrence, the dose reduction to a dose of 10mg from a dose 20mg, or suspension of administration should be considered.
Contraindications
Vonoprazan is contraindicated in: Patients with hypersensitivity to Vonoprazan or to any excipient of the product. Patients receiving atazanavir sulphate, nelfinavir or rilpivirine hydrochloride.
Pregnancy & Breastfeeding
Vonoprazan should be used in pregnant women or women having possibility of being pregnant only if the expected therapeutic benefit is thought to outweigh any possible risk. It is advisable to avoid the administration of Vonoprazan to nursing mothers. However, when the administration is indispensable, nursing should be discontinued.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Use in the elderly: Since the physiological functions such as hepatic or renal function are decreased in elderly patients in general, Vonoprazan should be carefully administered.Use in children less than 18 years of age: The safety and efficacy of Vonoprazan in children and adolescence have not been established. Therefore, the administration of Vonoprazan is not recommended in children and adolescents below 18 years of age.Patients with renal impairment: No dose adjustment of Vonoprazan is recommended in patients with mild to moderate renal impairment (eGFR 30 to 89 mL/min). Avoid the use of Vonoprazan in patients with severe renal impairment (eGFR < 30 mL/min)Patients with hepatic impairment: No dose adjustment of Vonoprazan is recommended in patients with mild hepatic impairment (Child-Pugh A). Avoid the use of Vonoprazan in patients with moderate to severe hepatic impairment (Child-Pugh B or C).
Overdose
There is no experience of overdose with Vonoprazan. Vonoprazan is not removed from the circulation by hemodialysis. If overdose occurs, treatment should be symptomatic and supportive.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store below 30°C, in a cool and dry place. Keep away from light. Keep all the medicine out of the reach of children.
Common questions about Venocid- 10 10 mg
What is Venocid- 10 10 mg Tablet?
Venocid- 10 10 mg Tablet is a medicine that contains Vonoprazan. It is made by Drug International Ltd., Gopalpur. It belongs to the Potassium competitive acid blocker group of medicines.
What is Venocid- 10 used for?
Venocid- 10 is used for: Gastroesophageal Reflux Disease, Peptic Ulcer, Helicobacter Pylori Infection, Cancer.
What are the side effects of Venocid- 10?
Following side effects have been reported with the use of Vonolend: Diarrhea, constipation, drug hypersensitivity (including anaphylactic shock), drug eruption, urticaria, hepatotoxicity, jaundice, rash, nausea, abdominal distension, gamma-glutamyl transferase increased, AST increased, Liver function test abnormal, ALT increased, ALP increased, LDH increased, y-GPT increased, edema and eosinophilia
Can I take Venocid- 10 during pregnancy or while breastfeeding?
Vonoprazan should be used in pregnant women or women having possibility of being pregnant only if the expected therapeutic benefit is thought to outweigh any possible risk. It is advisable to avoid the administration of Vonoprazan to nursing mothers. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Venocid- 10?
There is no experience of overdose with Vonoprazan. Vonoprazan is not removed from the circulation by hemodialysis. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Venocid- 10?
Store below 30°C, in a cool and dry place. Keep away from light.
Do I need a prescription for Venocid- 10?
Venocid- 10 is a prescription (Rx) medicine. Take it as your doctor advises.