Indications & Uses
Typar TCV is indicated for active immunization against infection caused by Salmonella typhi in infants, children, adolescents and adults aged >6 months to <45 years.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
A single 0.5 mL dose of the vaccine should be administered intramuscularly in the deltoid muscle of upper arm if muscle mass is adequate for children 2 years and above, adolescents and adults. For infants and toddlers aged >6 months to <2 years of age, the vaccine should be administered intramuscularly in the vastus lateralis muscle on anterolateral aspect of thigh. This vaccine should not be injected into the gluteal area or in any areas where there may be a nerve trunk.
Side Effects
The most frequently reported local adverse events after administration of Biological E's Typar TCV Vi Conjugate vaccine were Injection Site Pain (4.50%), Injection Site erythema (0.64%) and Injection site Swelling (0.32%). These usually occurred within first 48 hours and disappeared within 2-3 days. The most frequently reported systemic adverse events were Pyrexia (2.25%), Vomiting (0.96%), Headache (0.64%), Fatigue (0.64%), Arthralgia (0.32%) and Rash (0.32%). No vaccine-related serious adverse events (SAEs) were reported in the clinical trial.
Cautions & Contraindications
Warnings & Precautions
Do not administer intravenously, intradermally or subcutaneously.Typar TCV protects against typhoid fever caused by Salmonella typhi. Protection is not conferred against Salmonella paratyphi and other non typhoidal Salmonellae.Adrenaline (epinephrine) injection, 1:1000 (1 mg/mL) must be immediately available in case of an acute anaphylactic reaction or any allergic reaction occurs due to any component of the vaccine. The vaccinee should remain under medical supervision for not less than 30 minutes after vaccination. Like all other vaccines, supervision and appropriate medical treatment should always be available to treat any anaphylactic reactions following immunization.
Contraindications
Hypersensitivity to any component of vaccine Pregnant & lactating women In case of fever and severe infection