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Other brands with the same active ingredient
These brands contain the same active ingredient (Etoricoxib). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Torento 120 is indicated for:
Pharmacology
Etoricoxib is a potent oral medicine that works by specifically blocking an enzyme called cyclooxygenase-2 (COX-2), and it does so both at normal treatment doses and at doses well above that range. The body has two related enzymes, COX-1 and COX-2, that play different roles. COX-1 supports everyday protective functions, such as keeping the stomach lining healthy and helping platelets clot normally. This is why older, non-selective NSAIDs, which block both COX-1 and COX-2, can cause stomach damage and interfere with normal blood clotting. COX-2, on the other hand, is mainly responsible for producing the substances that cause pain, inflammation, and fever. By selectively blocking COX-2 rather than COX-1, etoricoxib relieves these symptoms while carrying a lower risk of stomach-related side effects and clotting problems. At daily doses up to 150 mg, etoricoxib blocks COX-2 in a dose-related manner without affecting COX-1, and it does not reduce the stomach's protective prostaglandin production.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and adolescents over 16 years:
Osteoarthritis: The usual dose is 30 mg once daily. If symptoms are not adequately relieved, the dose may be increased to 60 mg once daily.
Rheumatoid arthritis: The usual dose is 90 mg once daily.
Ankylosing spondylitis: The usual dose is 90 mg once daily.
Acute gouty arthritis: The usual dose is 120 mg once daily. In clinical trials, this dose was given for 8 days at a time.
Postoperative dental surgery pain: The usual dose is 90 mg once daily, for no more than 3 days. Some patients may need additional pain relief after surgery.
Because the cardiovascular risks of Etoricoxib can increase with higher doses and longer use, it should be taken at the lowest effective dose for the shortest time needed. Doctors should periodically reassess whether continued treatment is still needed and how well it is working, particularly for patients being treated for osteoarthritis.
Side Effects
Side-effects that have been reported with etoricoxib include palpitations, tiredness, flu-like symptoms, and easy bruising. Less commonly, it may cause dry mouth, a change in taste, mouth ulcers, changes in appetite or weight, an irregular heartbeat (atrial fibrillation), a transient ischaemic attack ("mini-stroke"), chest pain, flushing, cough, breathlessness, nosebleeds, anxiety, reduced mental sharpness, tingling or numbness, disturbances in blood electrolyte levels, and muscle or joint pain. Very rarely, it may cause confusion or hallucinations.
Cautions & Contraindications
Warnings & Precautions
Caution is advised when treating patients most at risk of gastrointestinal complications from NSAIDs, including elderly patients, those taking another NSAID or acetylsalicylic acid at the same time, or those with a prior history of gastrointestinal disease such as ulceration and GI bleeding. Patients with significant cardiovascular risk factors (for example, hypertension, high cholesterol, diabetes, or smoking) should be treated with Ezepain only after careful consideration. Ezepain can reduce prostaglandin formation and, in turn, renal blood flow, which may impair kidney function; monitoring of renal function should be considered in such patients. Caution should also be used in patients with a history of heart failure, left ventricular dysfunction, or hypertension, and in those with pre-existing fluid retention from any cause. Patients showing symptoms or signs of liver problems, or an abnormal liver function test, should be monitored closely. If signs of liver impairment appear, or if liver function tests remain abnormal at three times the upper limit of normal, Ezepain should be stopped. Treatment should also be discontinued at the first sign of skin rash, mucosal lesions, or any other symptom of hypersensitivity. Ezepain may mask fever and other signs of inflammation, so this should be kept in mind during evaluation. Finally, caution is needed when Ezepain is taken together with warfarin or other oral anticoagulants.
Contraindications
Hypersensitivity to the active substance or to any of the excipients. Active peptic ulcer disease or active gastrointestinal (GI) bleeding. A history of bronchospasm, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria, or other allergic-type reactions after taking acetylsalicylic acid or NSAIDs, including COX-2 (cyclooxygenase-2) inhibitors. Pregnancy and breastfeeding. Severe liver impairment (serum albumin below 25 g/L, or a Child-Pugh score of 10 or above). Estimated renal creatinine clearance below 30 ml/min. Children and adolescents under 16 years of age. Inflammatory bowel disease. Congestive heart failure (NYHA class II-IV). Hypertension where blood pressure remains persistently above 140/90 mmHg despite treatment. Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease.
Pregnancy & Breastfeeding
The use of Etoricoxib is not recommended in women who are trying to conceive, in the same way as with any drug known to inhibit COX-2. It is not known whether Etoricoxib passes into human breast milk, although it is excreted in the milk of lactating rats. Women who take Etoricoxib must not breastfeed.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Etoricoxib was given as a single dose of up to 500 mg, and as multiple doses of up to 150 mg/day for 21 days, without significant toxicity. If an overdose does happen, the usual supportive measures are reasonable. These include removing unabsorbed material from the GI tract, monitoring the patient clinically, and starting supportive therapy if it is needed.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Etoricoxib below 30°C, and protect it from light and moisture. Keep it out of reach of children.
Drug Interactions
Common questions about Torento 120 120 mg
What is Torento 120 120 mg Tablet?
Torento 120 120 mg Tablet is a medicine that contains Etoricoxib. It is made by SinoHealth Pharmaceuticals Ltd. It belongs to the Non-steroidal Anti-inflammatory Drugs (NSAIDs) group of medicines.
What is Torento 120 used for?
Torento 120 is used for: Pain, Osteoarthritis, Rheumatoid Arthritis, Inflammation.
What are the side effects of Torento 120?
Side-effects that have been reported with etoricoxib include palpitations, tiredness, flu-like symptoms, and easy bruising. Less commonly, it may cause dry mouth, a change in taste, mouth ulcers, changes in appetite or weight, an irregular heartbeat (atrial fibrillation), a transient ischaemic attack ("mini-stroke"), chest pain, flushing, cough, breathlessness, nosebleeds, anxiety, reduced mental sharpness, tingling or numbness, disturbances in blood electrolyte levels, and muscle or joint pain.
Can I take Torento 120 during pregnancy or while breastfeeding?
The use of Etoricoxib is not recommended in women who are trying to conceive, in the same way as with any drug known to inhibit COX-2. It is not known whether Etoricoxib passes into human breast milk, although it is excreted in the milk of lactating rats. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Torento 120?
Etoricoxib was given as a single dose of up to 500 mg, and as multiple doses of up to 150 mg/day for 21 days, without significant toxicity. If an overdose does happen, the usual supportive measures are reasonable. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Torento 120?
Keep Etoricoxib below 30°C, and protect it from light and moisture. Keep it out of reach of children.
Can I take other medicines with Torento 120?
Some medicines can interact with Etoricoxib, for example: Tacrolimus, Cyclosporine, Warfarin Sodium. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Torento 120?
Torento 120 is a prescription (Rx) medicine. Take it as your doctor advises.