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Other brands with the same active ingredient
These brands contain the same active ingredient (Temazepam). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Temazepam-10 is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Recommended dosing for adults is 15 mg taken at bedtime, though some patients respond well to as little as 7.5 mg, while others may require up to 30 mg. For transient insomnia, 7.5 mg is often enough to help patients fall asleep more quickly. Elderly or debilitated patients should generally start at 7.5 mg, with the dose adjusted once their individual response is known. Pediatric Use: Safety and effectiveness in children have not been established.
Side Effects
The most common side effects of Temixil are: drowsiness headache tiredness nervousness dizziness nausea
Cautions & Contraindications
Warnings & Precautions
Temixil should be started at a low dose of 7.5 mg in elderly and debilitated patients, since the risk of oversedation, dizziness, confusion, and/or ataxia rises substantially with larger benzodiazepine doses in this group. It should be given cautiously to patients with severe depression or any sign of underlying depression, since suicidal tendencies may be present and protective measures may be needed. The usual precautions apply for patients with impaired kidney or liver function and for those with chronic lung insufficiency. If Temixil is combined with other drugs known to have hypnotic or CNS-depressant effects, the potential for additive effects should be considered. A synergistic effect is also possible when Temixil is given together with diphenhydramine: one stillbirth at term was reported 8 hours after a pregnant patient received both drugs, though a cause and effect relationship has not been established.
Contraindications
Temazepam may cause fetal harm when given to a pregnant woman. Several studies have suggested a higher risk of congenital malformations with diazepam and chlordiazepoxide when these are used during the first trimester of pregnancy. When a benzodiazepine hypnotic is taken at normal doses during the last weeks of pregnancy, it can cross the placenta and cause central nervous system (CNS) depression in the newborn. Reproduction studies of temazepam were carried out in rats and rabbits. In a perinatal and postnatal study in rats, oral doses of 60 mg/kg/day increased nursling mortality. Teratology studies in rats showed increased fetal resorption at doses of 30 and 120 mg/kg in one study, and, in a second study, a higher occurrence of rudimentary ribs (a recognised skeletal variant) at doses of 240 mg/kg or higher. In rabbits, occasional abnormalities such as exencephaly and fused or asymmetric ribs were seen, but not in a dose related way. These were not seen in the concurrent control group, though they have been reported to occur randomly among historical controls. At doses of 40 mg/kg or higher, there was a higher rate of the 13th rib variant compared with both concurrent and historical controls. Temazepam is contraindicated in women who are or may become pregnant. If it is used during pregnancy, or if a patient becomes pregnant while taking it, she should be told about the potential risk to the fetus. Patients should be advised to stop the drug before trying to become pregnant. Whether a woman of childbearing potential could already be pregnant when treatment is started should also be considered.