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Other brands with the same active ingredient
These brands contain the same active ingredient (Ursodeoxycholic Acid). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Liconor is used to treat cholestasis (jaundice), viral hepatitis, alcoholic fatty liver, Primary Billiary Cirrhosis (PBC) and Primary Sclerosing Cholangitis (PSC). It is also used for dissolution of gallstones and for Non-Alcoholic Steato Hepatitis (NASH).
Pharmacology
Ursodeoxycholic Acid is a naturally occurring bile acid used to treat various hepatobiliary disorders. It works mainly by reducing the amount of cholesterol secreted into bile. It does this through several mechanisms: reducing cholesterol absorption, suppressing cholesterol synthesis in the liver, and leaving bile acid synthesis uninhibited. Therefore, it shifts bile composition from a supersaturated state to an unsaturated one. Ursodeoxycholic Acid also promotes the formation of liquid cholesterol crystal complexes, which help move cholesterol out of the gallbladder and into the intestine so it can be expelled from the body.
Ursodeoxycholic Acid improves cholestatic liver diseases by protecting cholangiocytes against the cytotoxic effects of hydrophobic bile acids, stimulating hepatobiliary secretion, and protecting hepatocytes against bile acid-induced cell death.
Ursodeoxycholic Acid is completely absorbed in the upper intestine, with peak serum concentration reached anywhere between 30 and 150 minutes, and an absorption rate of 60-80%. After being absorbed, it enters the portal vein and is extracted from the portal blood by the liver, where it is conjugated with an amino acid, either glycine or taurine, and then secreted into the hepatic bile ducts. Small quantities appear in the general circulation, and only very small amounts are excreted in urine. Its biologic half-life ranges between 3.5 and 5.8 days.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dissolution of gall stones: 8 to 12 mg/kg/day, given either as a single night time dose or in divided doses.
Primary Billiary Cirrhosis: 10 to 15 mg/kg/day in 2 to 4 divided doses.
Acute Viral Hepatitis: 600 mg/day.
Alcoholic Fatty Liver: 300 mg/day.
Primary Sclerosing Cholangitis: 25 to 30 mg/kg/day.
Dissolution of Gallstones and Non-Alcoholic Steato Hepatitis: 13 to 15 mg/kg/day.
Side Effects
Commonly reported side effects include nausea, vomiting, diarrhoea, itching (pruritus), and calcification of gallstones.
Cautions & Contraindications
Warnings & Precautions
Ursodeoxycholic acid should be used with caution in patients who have liver disease.
Contraindications
Non-functioning gallbladder, calcified gallstones, pigmented gallstones, and inflammatory bowel disease.
Pregnancy & Breastfeeding
Pregnancy category B. No evidence of harm has been reported in pregnancy. It has been used effectively to treat cholestasis of pregnancy during the last trimester without any side effects. No problems have been documented in humans regarding breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Ursodeoxycholic Acid below 25° C, away from light and moisture. Also keep the medicine out of the reach of children.
Drug Interactions
Common questions about Stener 300 mg 300 mg
What is Stener 300 mg 300 mg Tablet?
Stener 300 mg 300 mg Tablet is a medicine that contains Ursodeoxycholic Acid. It is made by Healthcare Pharmaceuticals Ltd. It belongs to the Anti-gallstones drugs: Bile Acids group of medicines.
What is Stener 300 mg used for?
Liconor is used to treat cholestasis (jaundice), viral hepatitis, alcoholic fatty liver, Primary Billiary Cirrhosis (PBC) and Primary Sclerosing Cholangitis (PSC). It is also used for dissolution of gallstones and for Non-Alcoholic Steato Hepatitis (NASH).
What are the side effects of Stener 300 mg?
Commonly reported side effects include nausea, vomiting, diarrhoea, itching (pruritus), and calcification of gallstones.
Can I take Stener 300 mg during pregnancy or while breastfeeding?
Pregnancy category B. No evidence of harm has been reported in pregnancy. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Stener 300 mg?
Keep Ursodeoxycholic Acid below 25° C, away from light and moisture. Also keep the medicine out of the reach of children.
Can I take other medicines with Stener 300 mg?
Some medicines can interact with Ursodeoxycholic Acid, for example: Cholestyramine, Elobixibat, Norgestrel + Ethinyl Estradiol + Ferrous Fumarate. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Stener 300 mg?
Stener 300 mg is a prescription (Rx) medicine. Take it as your doctor advises.