Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Save on this medicine
Same active ingredient — pay up to 1% less
These brands contain the same active ingredient (Spironolactone). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Spiretic is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Heart failure: Treatment is started at 25 mg once daily. Hypertension: Treatment is started at 25 to 100 mg daily, given as a single dose or in divided doses. Essential hypertension: For adults, a starting daily dose of 50 to 100 mg of Spironolactone, given as a single dose or in divided doses, is recommended. Primary hyperaldosteronism: Spironolactone may be used as an initial diagnostic measure to provide presumptive evidence of primary hyperaldosteronism while patients remain on their normal diet. Edema in adults (congestive heart failure, hepatic cirrhosis, or nephrotic syndrome): A starting daily dose of 50 to 100 mg of Spironolactone, given as a single dose or in divided doses, is recommended; the dose may range from 25 to 200 mg daily. Hypokalemia: Spironolactone at a dose of 25 mg to 100 mg daily is useful for treating diuretic-induced hypokalemia when oral potassium supplements or other potassium-sparing regimens are considered inappropriate.
Side Effects
Breast enlargement (gynaecomastia) can occur in men taking Spirolac. The chance of this happening appears to depend on both the dose and how long the medicine is taken, and it usually goes away once Spirolac is stopped. In rare cases, some breast enlargement may remain. Other side effects reported with Spirolac include: stomach and bowel problems such as cramping and diarrhoea; drowsiness; tiredness or lack of energy; headache; skin rashes (raised, spotty or red patches); hives; confusion; fever caused by the medicine; loss of coordination (ataxia); impotence; irregular or missed periods; and bleeding after the menopause. These side effects usually go away once the medicine is stopped.
Cautions & Contraindications
Warnings & Precautions
Anyone taking a diuretic should be monitored for signs of fluid or electrolyte imbalance, such as low magnesium (hypomagnesemia), low sodium (hyponatremia), hypochloremic alkalosis, and high potassium (hyperkalemia). Checking electrolyte levels in the blood and urine is especially important if the patient is vomiting heavily or receiving fluids by drip or injection. High potassium levels can develop in patients with reduced kidney function or a high potassium intake, and this can trigger irregular heart rhythms, which may be fatal. For this reason, potassium supplements should not normally be given alongside this medicine.
Contraindications
Spironolactone should not be used in acute renal insufficiency, significant impairment of renal function, anuria, hyperkalaemia, or known sensitivity to Spironolactone.