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These brands contain the same active ingredient (Doxepin). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and children over 12 years: apply a thin layer 3 to 4 times daily. The usual maximum is 3 g per application and 12 g in total per day. The area covered should be less than 10% of the body surface area. Use in children: Doxiderm cream is not recommended for pediatric patients, as safe conditions for its use in children have not been established. Use in elderly patients: Dose selection for elderly patients should be cautious, usually starting at the low end of the dosing range. This reflects the greater frequency of reduced liver, kidney or heart function, as well as other illnesses or concurrent drug therapy, in this age group.
Side Effects
Doxepin may cause drowsiness. When applied to the skin, it can cause local burning, stinging, irritation, tingling or a rash. Systemic side effects have also been reported, including antimuscarinic effects, headache, fever, dizziness and gastrointestinal disturbances.
Cautions & Contraindications
Warnings & Precautions
Care is needed in people who are prone to angle-closure glaucoma, urinary retention, severe liver impairment, or mania, and also during pregnancy and breast-feeding. Because doxepin can cause drowsiness, it may impair the ability to perform skilled tasks such as driving, so patients should take care.
Contraindications
Doxepin should not be used in people with untreated narrow-angle glaucoma or a tendency to urinary retention, because it has an anticholinergic effect. It is also not suitable for anyone who has previously shown sensitivity to any of its components.